Micro/nano cell and molecular sensors [electronic resource] / Ping Wang, Chunsheng Wu, Ning Hu, K. Jimmy Hsia, editors.

Chapter 1: Introduction; 1.1 Introduction; 1.2 Micro/NanoCell- and Molecule-Based Biosensors; 1.3 Characteristics of Micro/Nano Cell- and Molecule-Based Biosensors; 1.4 Types of Micro/NanoCell and Molecule-Based Biosensors; 1.5 Summary; References; Chapter 2: Micro/NanoBiosensors for Living Cell and Molecule Analysis; 2.1 Introduction; 2.2 Traditional Cell- and Molecular-Based Biosensors; 2.2.1 Microelectrode Array; 2.2.2 Impedance Biosensor; 2.2.3 Field-Effect Transistor; 2.2.4 Light-Addressable Potentiometric Sensor; 2.3 Novel Micro/Nano cell- and Molecular-Based Biosensors

2.3.1 Nanoscale FET2.3.1.1 Fabrication of Nanoscale Device; 2.3.1.2 Characterization and Application of Nanoscale FET Devices; 2.3.2 Nanopillar and Nanotube Electrode Array; 2.3.2.1 Fabrication of Nanoelectrode Array; 2.3.2.2 Characterization and Application of Nanoelectrode Array; 2.3.3 Nanomaterial Modified Biosensor; 2.3.3.1 Fabrication of Nanotube-Modified FET; 2.3.3.2 Characterization and Application of Nanotube-Modified FET; 2.4 Summary; References; Chapter 3: Label-Free DNA Biosensors with Field-Effect Devices; 3.1 Introduction; 3.2 Principle of FED-Based DNA Biosensors

3.2.1 Mechanisms of DNA Hybridization and Signal Generation3.2.2 Label-Free Detection of DNA Hybridization with FEDs; 3.3 Design and Fabrication of FEDs for DNA Sensing; 3.3.1 Coupling of DNA Molecules with FEDs; 3.3.2 Fabrication of FEDs for DNA Sensing; 3.4 Application of FED-Based DNA Biosensors; 3.4.1 Label-Free DNA Assays; 3.4.2 Label-Free Detection of SNPs; 3.5 Summary; References; Chapter 4: Micro/Nano Cell-Substrate Impedance Biosensors; 4.1 Introduction; 4.2 Theory of Cell Impedance Biosensors; 4.2.1 ECIS Cell Impedance Model; 4.2.2 Detection Principle of Cell Growth and Pulse

4.2.3 Cell Index4.3 ECIS-Based Biosensors and Measurement; 4.3.1 Chip Fabrication; 4.3.2 Surface Modification; 4.3.3 Detection System; 4.4 Application in Biomedicine and Food Analysis; 4.4.1 Drug Screening; 4.4.2 Environment Monitoring; 4.4.3 Food Analysis; 4.4.4 Cancer Research; 4.4.5 Other Applications; 4.5 Summary; References; Chapter 5: Micro/Nano Cell Potential Biosensors; 5.1 Introduction; 5.2 Theory of Cell Potential Biosensors; 5.2.1 H-H Model of Cardiomyocyte Action Potential; 5.2.2 Cell Potential Sensor Model; 5.2.3 Detection Principle of EFP

5.3 MEA-Based Biosensors and Measurement5.3.1 MEA Chip Design and Fabrication; 5.3.2 MEA Chip Surface Modification; 5.3.2.1 Surface Hydrophilicity Improvement Method; 5.3.2.2 Protein Modification Method; 5.3.2.3 Special Structure Manufacturing Method; 5.3.3 Detection System and EFP Measurement; 5.4 Application in Biomedicine and Food Analysis; 5.4.1 Cardiac Pathology Research; 5.4.2 Cardiac Safety Evaluation; 5.4.3 Food Analysis; 5.4.4 Other Applications; 5.5 Summary; References; Chapter 6: Micro/Nano Neuronal Network Cell Biosensors; 6.1 Introduction; 6.2 The Development of Neural Networks