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Foreword; Acknowledgments; Contents; Editor's Notes; 1 Bioactive Materials: Definitions and Application in Tissue Engineering and Regeneration Therapy; Abstract; 1 Biomaterials History; 2 Bioactivity Concept and Bioactive Materials; 3 Introduction to Stem Cells for Regeneration Therapy; 4 Bioactive Ceramics and Stem Cells: A Synergistic Approach for Regeneration Therapy; 4.1 Hydroxyapatite; 4.2 TCP and Biphasic Calcium Phosphates; 4.3 Silicate Nanoclay; 4.4 Bioactive Glass; 4.5 Polymers and Biomaterials; 4.6 Emerging Carbon Based Nanomaterials; Acknowledgments; References

2 An Introduction and History of the Bioactive GlassesAbstract; 1 Bioactive Glasses as Biomaterials; 2 Implantation and Transplantation; 3 Elements Required by Human Body; 4 Design Criteria for Biomaterials/Bioactive Glasses; 5 Different Types of Bioactive Glasses; 5.1 Silicate Glasses; 5.2 Borate/Borosilicate Glasses; 5.3 Phosphate Glasses; 5.4 Doped Glasses; 5.5 Metallic Glasses; 5.6 Mesoporous Glasses; 6 History and State of Art of Bioglasses; 7 Techniques for Bioactive Glass Fabrication; 8 Conclusions; References; 3 Structure and Percolation of Bioglasses; Abstract

1 Introduction About Bioglass2 Soda-Lime Silicate and Bioactive Soda-Lime Phosphosilicate Glasses Structure; 3 Interaction Mechanisms Between Living Tissue and Glasses Soda-Lime Phosphosilicate; 3.1 Cations and Anions Diffusion Through the Glass Matrix; 3.2 Glass Network Hydrolysis; 3.3 Silica Enriched Layer Formation on the Glass Surface; 3.4 Glass Network Attack by OH-Ions; 3.5 Ca2+ and PO43− rich film formation in material surface; 3.6 HA Precipitation on the Material Surface; References

4 The Evolution, Control, and Effects of the Compositions of Bioactive Glasses on Their Properties and ApplicationsAbstract; 1 Introduction; 1.1 Glass Structure; 1.2 Therapeutic Ion Release; 2 Composition Effects on Properties and Applications of Bioactive Glasses; 2.1 Effect of Sodium; 2.2 Effect of Calcium; 2.3 Effect of Fluorine; 2.4 Effects of Strontium; 2.5 Effect of Zinc; 2.6 Effect of Magnesium; 2.7 Effects of Manganese; 2.8 Effect of Cobalt; 2.9 Effects of Copper; 2.10 Effect of Silver; 2.11 Effects of Gallium; 2.12 Effect of Cerium; 3 Summary and Outlook; Acknowledgments; References

5 What Can We Learn from Atomistic Simulations of Bioactive Glasses?Abstract; 1 Introduction; 2 How to Obtain the Glass Structure Models: A Brief Overview of Classical and Ab Initio Molecular Dynamics; 2.1 Classical Molecular Dynamics; 2.2 Ab Initio Molecular Dynamics; 2.3 Mixed Classical-AI MD Procedure; 3 Structural Descriptors for Bioactivity Prediction; 3.1 The Network Connectivity; 3.1.1 Strength of the Glass Network; 3.1.2 Strength of Modifier-Mediated Cross-Link Interactions; 3.2 Clustering of Network and Modifying Cations; 4 SiO2-Based Bioactive Glass Systems

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