Therapeutic and diagnostic nanomaterials / Devasena T.

Introduction; 1 Diagnostic and Therapeutic Nanomaterials; 1.1 Why Are Nanoparticles Ideal Diagnostic and Therapeutic Agents?; 1.2 Nanotheranostic Candidates; 1.3 Safety Concerns with Medically Important Nanoparticles; References; 2 Multifunctional Nanoparticles; 2.1 Stabilizing Ligands; 2.1.1 Biomolecules; 2.1.2 Avidin-Biotin Conjugate; 2.2 Targeting Ligands; 2.2.1 Antibodies; 2.2.2 Antibody Fragments/Antibody Derivatives; 2.2.3 Peptides; 2.2.4 Aptamers; 2.2.5 Small Targeting Molecules; 2.3 Imaging Ligands; 2.4 Biocompatibility Ligands; 2.5 Anti-immunogenic Ligands; References

3 Biomarkers3.1 Biochemical Markers; 3.1.1 Cardiac Markers; 3.1.2 Cytokines; 3.1.3 Cancer Markers; 3.1.4 Cell Adhesion Molecules (CAMs); 3.1.5 Enzymes; 3.1.6 Hematological Biomarkers; 3.1.7 Oxidative Stress Markers; 3.2 Genetic Markers; 3.2.1 Single Locus Markers; 3.2.2 Multiple Loci Markers; 3.2.3 Examples of Genetic Markers; 3.3 Histopathological Markers; References; 4 Diagnostic and Therapeutic Techniques; 4.1 Diagnostic Techniques Using Nanoparticles; 4.2 Therapeutic Techniques Using Nanoparticles; References; 5 Nanotoxicity and Risk Assessment; 5.1 CNT Toxicity

5.2 Silica and Titania Nanoparticles5.3 Fullerene; 5.4 Quantum Dots; 5.5 Manganese Nanoparticles; References; 6 Applications of Select Nanomaterials; 6.1 Dendrimers; 6.1.1 Dendrimers in Therapeutic Applications; 6.1.2 Nanoscale Containers; 6.1.3 Dendrimers in Gene Transfection; 6.1.4 Dendrimers in Diagnostic Applications; 6.2 Antibodies; 6.2.1 Blood-Brain Barrier; 6.2.2 Nanoimmunosensors; 6.2.3 Types of Immunosensors; 6.2.4 Preparation of HDL-like Nanoparticles; 6.2.5 Plaques in an ApoE-/- Model; 6.2.6 Gold Nanoparticles

6.2.6.1 Applications of Gold Nanoparticles with Enhanced Raman Spectroscopy6.3 Lipid-Based Nanocarriers; 6.3.1 Liposomes; 6.3.1.1 Stealth Liposomes: The Second-Generation Liposomes; 6.3.1.2 Applications of Nanoliposomes; Liposomal Anticancer Agents; Liposomal Anti-infective Drugs; Vaccine Delivery; Diagnostic Applications of Liposomes; 6.3.1.3 Solid-Lipid Nanoparticles; Applications of SLNs; 6.3.1.4 Cubosomes; Cubosomes for Ocular Inflammation; 6.4 Viral Nanoparticles; 6.4.1 Pharmacokinetics; 6.4.2 Disadvantages: Nonspecific Interaction and Immunogenicity; 6.4.3 Applications

6.4.3.1 VNPs as Imaging Probes and Drug Carriers for Vascular Endothelial Cells6.4.3.2 CPMVs as Carriers for Delivering Cargo into the Central Nervous System; 6.5 Nanomaterial-Based Biomedical Devices; 6.5.1 Micropumps; 6.5.1.1 Components of Micropumps; 6.5.1.2 Applications and Advantages of a Silicon-Based HPMP; 6.5.2 Microneedles; 6.5.2.1 Applications of Microneedles; 6.5.3 Implantable Microchip Devices for Drug Delivery; 6.5.4 Nanorobots; 6.5.4.1 Tools or Components of Nanorobots; 6.5.4.2 Nanorobot Locomotion; 6.5.4.3 Power for the Navigation of Nanorobots; 6.5.4.4 Tracking of Nanorobots