000777087 000__ 04716cam\a2200517Ii\4500 000777087 001__ 777087 000777087 005__ 20230306142656.0 000777087 006__ m\\\\\o\\d\\\\\\\\ 000777087 007__ cr\nn\nnnunnun 000777087 008__ 160823t20162017si\a\\\\ob\\\\000\0\eng\d 000777087 019__ $$a957606301 000777087 020__ $$a9789811023569$$q(electronic book) 000777087 020__ $$a9811023565$$q(electronic book) 000777087 020__ $$z9789811023552 000777087 020__ $$z9811023557 000777087 035__ $$aSP(OCoLC)ocn957156920 000777087 035__ $$aSP(OCoLC)957156920$$z(OCoLC)957606301 000777087 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dIDEBK$$dGW5XE$$dEBLCP$$dYDX$$dOCLCF$$dN$T$$dIDB$$dUAB$$dMERUC$$dIOG 000777087 049__ $$aISEA 000777087 050_4 $$aQD96.M3 000777087 08204 $$a543/.65$$223 000777087 1001_ $$aHosseini, Samira,$$eauthor. 000777087 24510 $$aFundamentals of MALDI-ToF-MS analysis :$$bapplications in bio-diagnosis, tissue engineering and drug delivery /$$cSamira Hosseini, Sergio O. Martinez-Chapa. 000777087 264_1 $$aSingapore :$$bSpringer,$$c[2016]. 000777087 264_4 $$c©2017 000777087 300__ $$a1 online resource (xi, 68 pages) :$$billustrations. 000777087 336__ $$atext$$btxt$$2rdacontent 000777087 337__ $$acomputer$$bc$$2rdamedia 000777087 338__ $$aonline resource$$bcr$$2rdacarrier 000777087 4901_ $$aSpringerBriefs in applied sciences and technology, Forensic and medical bioinformatics,$$x2191-530X 000777087 504__ $$aIncludes bibliographical references. 000777087 5050_ $$aPreface; Acknowledgment; Contents; 1 Principles and Mechanism of MALDI-ToF-MS Analysis; Abstract; 1.1 Background of MALDI-ToF-MS; 1.2 Applications of MALDI-ToF-MS; 1.2.1 Biochemistry; 1.2.2 Organic Chemistry; 1.2.3 Polymer Chemistry; 1.2.4 Microbiology; 1.2.5 Medicine; 1.2.6 Nanotechnology; 1.3 Ionization Mechanism; 1.4 Time of Flight Mass Spectrometry Mechanism; 1.5 Detection Modes; 1.5.1 Linear Mode; 1.5.2 Reflection Mode; 1.6 Laser Range in MALDI; 1.7 Matrix Selection; 1.7.1 Limitations of Matrices; 1.8 Ionizing Agent Selection; 1.9 Fundamentals of Sample Preparation for MALDI Analysis 000777087 5058_ $$a1.9.1 Analyzable and Non-analyzable Polymers1.9.2 Sample Preparation Techniques; 1.9.2.1 Dried-Droplet; 1.9.2.2 Fast Crystallization; 1.9.2.3 Spin Coating; 1.9.2.4 Layer by Layer; 1.9.2.5 Electrospray Deposition; 1.10 Mass Discrimination; 1.10.1 Alternative Solutions for Overcoming Mass Discrimination; 1.11 MALDI Coupling; 1.11.1 Ion-Mobility Time of Flight Mass Spectrometry (IMS-ToF-MS); 1.11.2 Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR-MS); 1.11.3 Thin Layer Chromatography (TLC); 1.11.4 Size Exclusion Chromatograph (SEC); References 000777087 5058_ $$a2 Fundamentals of Biosensors and Application of MALDI-ToF-MS in Bio-diagnostic DomainAbstract; 2.1 Biosensors; 2.2 Synthesis of Poly Methyl Methacrylate-Co-Methacrylic Acid P(MMA-Co-MAA) and Preparation of the Biochips; 2.3 Sample Preparation for MALDI Analysis; 2.4 MALDI Data Interpretation; 2.4.1 Different Species as the Possible Products of Soft Ionization; 2.4.2 General Structure of P(MMA-Co-MAA); 2.4.3 MALDI Analysis of PMMA; 2.4.4 MALDI Analysis of P(MMA-Co-MAA); 2.4.5 End-Group Analysis; 2.5 Role of MALDI Analysis in Bio-sensing Application of P(MMA-Co-MAA); 2.5.1 Reaction's Parameters 000777087 5058_ $$a2.5.2 Chemistry Aspect2.5.3 Physical Aspect; References; 3 Fundamentals of Tissue Engineering and Application of MALDI-ToF-MS in Analysis of the Scaffold Materials; Abstract; 3.1 Tissue Engineering; 3.2 Synthesis of Poly Octanediol Citrate Acid-Sebacate Acid P(OCS) and Preparation of the Scaffold; 3.3 MALDI Analysis of P(OCS) and Sample Preparation; 3.4 MALDI Data Interpretation; 3.5 Role of MALDI Analysis in Tissue Engineering Application of P(OCS); 3.5.1 Reaction's Parameters; 3.5.2 Chemistry Aspect; 3.5.3 Mechanical Aspect; References 000777087 5058_ $$a4 Fundamentals of Drug Delivery Systems and Application of MALDI-ToF-MS in Drug DeliveryAbstract; 4.1 Drug Delivery; 4.2 Synthesis of PCLT-CA and Preparation of Elastomeric Films and Coatings; 4.3 Sample Preparation for MALDI Analysis; 4.4 MALDI Data Interpretation; 4.5 The Role of MALDI Analysis in Drug Delivery Application of PCLT-CA; 4.5.1 Chemistry Aspect; 4.5.2 Mechanical Aspect; References; Summary 000777087 506__ $$aAccess limited to authorized users. 000777087 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 26, 2016). 000777087 650_0 $$aMatrix-assisted laser desorption-ionization. 000777087 7001_ $$aMartínez Chapa, Sergio Omar,$$eauthor. 000777087 77608 $$iPrint version:$$z9789811023552$$z9811023557$$w(OCoLC)953709754 000777087 830_0 $$aSpringerBriefs in applied sciences and technology.$$pForensic and medical bioinformatics. 000777087 852__ $$bebk 000777087 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-10-2356-9$$zOnline Access$$91397441.1 000777087 909CO $$ooai:library.usi.edu:777087$$pGLOBAL_SET 000777087 980__ $$aEBOOK 000777087 980__ $$aBIB 000777087 982__ $$aEbook 000777087 983__ $$aOnline 000777087 994__ $$a92$$bISE