000777441 000__ 04773cam\a2200529Mi\4500 000777441 001__ 777441 000777441 005__ 20230306142716.0 000777441 006__ m\\\\\o\\d\\\\\\\\ 000777441 007__ cr\nn\nnnunnun 000777441 008__ 161105t20162017sz\\\\\\o\\\\\000\0\eng\d 000777441 019__ $$a960718825 000777441 020__ $$a9783319435800$$q(electronic book) 000777441 020__ $$a3319435809$$q(electronic book) 000777441 020__ $$z9783319435787 000777441 035__ $$aSP(OCoLC)ocn960166347 000777441 035__ $$aSP(OCoLC)960166347$$z(OCoLC)960718825 000777441 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dOCLCO$$dGW5XE$$dOCLCQ$$dOCLCF$$dUAB$$dCASUM$$dOCLCO$$dIDEBK$$dOCLCO$$dMERUC$$dIOG 000777441 049__ $$aISEA 000777441 050_4 $$aQR406$$b.H685 2017 000777441 08204 $$a616.9/11$$223 000777441 08204 $$a610 000777441 24500 $$aHPV infection in head and neck cancer /$$cWojciech Golusiński, C. René Leemans, Andreas Dietz, editors. 000777441 260__ $$aCham :$$bSpringer,$$c2016, ©2017. 000777441 300__ $$a1 online resource (257 pages). 000777441 336__ $$atext$$btxt$$2rdacontent 000777441 337__ $$acomputer$$bc$$2rdamedia 000777441 338__ $$aonline resource$$bcr$$2rdacarrier 000777441 4901_ $$aRecent Results in Cancer Research ;$$vv. 206 000777441 5050_ $$aEpidemiology and Molecular Biology of HPV Positive HNSCC; 1 HPV in Head and Neck Cancer-30ßYears of History; Abstract; 1 Introduction; 2 Milestones; 3 HPV and Oral Cavity Cancer; 4 HPV and Palatine Tonsil Cancer; 5 HPV and Sinonasal Cancer; 6 HPV and Nasopharyngeal Cancer; 7 HPV and Laryngeal Cancer; References; 2 Epidemiology of HPV-Positive Tumors in Europe and in the World; Abstract; 1 The Contribution of HPV in the Etiology of HNCs; 1.1 The ICO Study on HPV in HNCs; 1.2 HPV-Type Distribution in HNCs; 2 Burden of HPV-Related HNCs. 000777441 5058_ $$a3 Determinants for HPV-Positive Head and Neck CancersReferences; 3 Molecular Patterns and Biology of HPV-Associated HNSCC; Abstract; 1 Introduction; 1.1 Genetic Progression Model of Head and Neck Cancer; 1.1.1 Precursor Lesions in the Mucosal Linings; 1.1.2 Field Cancerization; 1.2 Cancer-Associated Changes in Head and Neck Carcinogenesis; 1.2.1 Different Genetics in HPV+ve and HPV-ve Tumors; 1.2.2 Different Expression Profiles HPV+ve and HPV-ve; 1.2.3 Regulation of Gene Expression by Epigenetics and MicroRNAs; 2 Conclusion; References. 000777441 5058_ $$a4 HPV Integration in Head and Neck Squamous Cell Carcinomas: Cause and ConsequenceAbstract; 1 Human Papillomavirusesßand Their Life Cycle; 2 Mechanisms Involved in and Approaches to Detect HPV Integration; 3 Identification of HPV Integration Sites in the Human Genome; 4 Consequences of Viral Integration: Viral Gene Expression; 5 Consequences of Viral Integration: Human Gene Expression; 6 HPV Integration in Relation to Viral Load, Methylated Genes and Outcome; References; 5 Risk Factors for Oral Infection with Human Papillomavirus; Abstract; 1 Introduction; 2 Age and Gender; 3 Sexual Behavior. 000777441 5058_ $$a4 Smoking5 HIV and Immunosuppression; 6 Conclusions; References; HPV Testing; 6 HPV-Related Head and Neck Squamous Cell Carcinomas; Abstract; 1 Introduction; 2 Squamous Cell Carcinoma: "Classic" Type ("Classic" SCC); 3 Squamous Cell Carcinoma: "Verrucous" Type ("Verrucous" SCC); 4 Squamous Cell Carcinoma: "Spindle Cell" ("Sarcomatoid") Type ("Spindle Cell" SCC); 5 Basaloid Squamous Cell Carcinoma (BSCC); 6 Papillary Squamous Cell Carcinoma (PSCC); 7 Adenosquamous Carcinoma (AdSC); 8 Nasopharyngeal Carcinoma/Lymphoepithelioma (NPC); 9 Sinonasal Undifferentiated Carcinoma (Anaplastic) (SNUC). 000777441 5058_ $$a10 ConclusionsReferences; 7 HPV Testing of Head and Neck Cancer in Clinical Practice; Abstract; 1 Introduction; 2 Indications for HPV Testing in the Head and Neck Cancer; 3 The Detection of HPV in Formalin-Fixed Paraffin-Embedded Biopsies Using Test Algorithms; 3.1 VU University Medical Centre HPV Test Algorithm; 3.2 The Johns Hopkins Medical Institutions HPV Test Algorithm; 4 p16 Immunohistochemistry; 5 Detection of HPV DNA; 6 Detection of HPV RNA; References; 8 Variation of HPV Subtypes with Focus on HPV-Infection and Cancer in the Head and Neck Region; Abstract; 1 Introduction; 2 Function of Oncogenic HPV Proteins. 000777441 506__ $$aAccess limited to authorized users. 000777441 588__ $$aDescription based on print version record. 000777441 650_0 $$aPapillomaviruses. 000777441 650_0 $$aNeck$$xCancer. 000777441 650_0 $$aHead$$xCancer. 000777441 7001_ $$aGolusiński, Wojciech. 000777441 7001_ $$aLeemans, C. René. 000777441 7001_ $$aDietz, Andreas. 000777441 77608 $$iPrint version:$$aGolusiński, Wojciech.$$tHPV Infection in Head and Neck Cancer.$$dCham : Springer International Publishing, ©2016$$z9783319435787 000777441 830_0 $$aRecent results in cancer research ;$$vv. 206. 000777441 852__ $$bebk 000777441 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-43580-0$$zOnline Access$$91397441.1 000777441 909CO $$ooai:library.usi.edu:777441$$pGLOBAL_SET 000777441 980__ $$aEBOOK 000777441 980__ $$aBIB 000777441 982__ $$aEbook 000777441 983__ $$aOnline 000777441 994__ $$a92$$bISE