000777800 000__ 04680cam\a2200541Mi\4500 000777800 001__ 777800 000777800 005__ 20230306142734.0 000777800 006__ m\\\\\o\\d\\\\\\\\ 000777800 007__ cr\nn\nnnunnun 000777800 008__ 161105t20162017sz\\\\\\o\\\\\001\0\eng\d 000777800 019__ $$a961910183$$a962017211 000777800 020__ $$a9783319416779$$q(electronic book) 000777800 020__ $$a3319416774$$q(electronic book) 000777800 020__ $$z9783319416755 000777800 020__ $$z3319416758 000777800 035__ $$aSP(OCoLC)ocn962154517 000777800 035__ $$aSP(OCoLC)962154517$$z(OCoLC)961910183$$z(OCoLC)962017211 000777800 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dOCLCO$$dN$T$$dYDX$$dGW5XE$$dIDEBK$$dN$T$$dOCLCQ$$dOCLCF$$dUAB$$dIOG 000777800 049__ $$aISEA 000777800 050_4 $$aRC268.4 000777800 08204 $$a616.99/4042$$223 000777800 24500 $$aAdipocytokines, energy balance, and cancer /$$cOfer Reizes, Nathan A. Berger, editors. 000777800 260__ $$aCham :$$bSpringer,$$c2016, ©2017. 000777800 300__ $$a1 online resource (306 pages). 000777800 336__ $$atext$$btxt$$2rdacontent 000777800 337__ $$acomputer$$bc$$2rdamedia 000777800 338__ $$aonline resource$$bcr$$2rdacarrier 000777800 4901_ $$aEnergy Balance and Cancer ;$$vv. 12 000777800 500__ $$aInvolvement ofßRBP4 andßSTRA6 in Cancer Cell Biology. 000777800 500__ $$aIncludes index. 000777800 5050_ $$aPreface; Contents; Contributors; Chapter 1: Adipocytes, Adipocytokines, andßCancer; Adipose Tissue; Adipocytokines andßCancer; Leptin; Adiponectin; Visfatin; Resistin; Apelin; Chemerin; Omentin; Nesfatin; Vaspin; Retinol-Binding Protein-4; Cytokines; Adipocytes and Tumor Metabolism; Conclusion; References; Chapter 2: Adiponectin, Obesity, andßCancer; Introduction; Adiponectin; Adiponectin Isoforms: Structural Considerations; Adiponectin Receptors; Adiponectin Modifications: Implication forßCancer; Adiponectin Signaling Pathways Related toßCancer. 000777800 5058_ $$aRole ofßAdiponectin in Tumor Initiation andßProgression Types ofßCancer Associated withßObesity andßDecreased Adiponectin; Colorectal Cancer; Endometrial Cancer; Prostate Cancer; Breast Cancer; Gastric Cancer; Hematological Malignancies; The L/A Ratio; Adiponectin Chemopreventatives; Concluding Remarks; References; Chapter 3: Leptin inßCancer: Epidemiology and Mechanisms; An Overview ofßtheßEarly Studies ofßLeptin and Breast Cancer; Epidemiological Studies ofßLeptin andßBreast Cancer; Recent In Vitro Studies. 000777800 5058_ $$aPreclinical Rodent Studies Evaluating Leptin's Effects onßMammary Tumor Development/Progression Leptin/Adiponectin Ratio; Leptin Antagonists; Leptin Advances Malignancy inßTumor Cells viaßAdditional Intrinsic Mechanisms; Leptin Effects onßtheßTumor Microenvironment also Contributes toßTumor Progression; Leptin's Role inßInflammation, Chemotaxis, andßAdaptive Immunity Impacts theßCancer Host's Immune Responses; Leptin and Non-breast Malignancies; Conclusions; References; Chapter 4: Leptin-Signaling Pathways asßTherapeutic Targets inßCancer. 000777800 5058_ $$aConnection Between Dysregulated Leptin Levels andßCancer Effect ofßLeptin onßCancer Progression andßMetastasis; Leptin asßaßRegulator or anßImportant Participant ofßVarious Oncogenic Pathways; Canonical Signaling Pathways ofßLeptin; Noncanonical Signaling-Functional Interactions ofßLeptin withßMultiple Pathways; Leptin, Estrogen, andßAromatase; Leptin, IGF1, Insulin, andßEGFR; Leptin, Notch, andßWnt/Catenin Pathway; Strategies toßInhibit Leptin Signaling; Direct Inhibition ofßLeptin Signaling Using Small Molecule Inhibitors. 000777800 5058_ $$aActivation ofßAdiponectin asßanßIndirect Strategy toßInhibit Leptin Conclusion; References; Chapter 5: Retinol Binding Protein 4: Role inßDiabetes andßCancer; Vitamin A: Absorption andßMetabolism; Retinoid-Binding Proteins; RBP4 andßTransport ofßRetinol inßtheßCirculation; Cellular Retinol-Binding Proteins; Vitamin A Uptake by Extrahepatic Tissues: RBP4 andßSTRA6; RBP4 Level Is Correlated withßObesity andßInsulin Resistance; RBP4 andßSTRA6 inßInsulin Resistance: AßMechanism ofßAction; Alternative Models forßUnderstanding How RBP4 Induces Insulin Resistance. 000777800 506__ $$aAccess limited to authorized users. 000777800 588__ $$aDescription based on print version record. 000777800 650_0 $$aCancer$$xMolecular aspects. 000777800 650_0 $$aAdipose tissues. 000777800 650_0 $$aBioenergetics. 000777800 7001_ $$aReizes, Ofer. 000777800 7001_ $$aBerger, Nathan A. 000777800 77608 $$iPrint version:$$aReizes, Ofer.$$tAdipocytokines, Energy Balance, and Cancer.$$dCham : Springer International Publishing, ©2016$$z9783319416755 000777800 830_0 $$aEnergy balance and cancer ;$$vv. 12. 000777800 852__ $$bebk 000777800 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-41677-9$$zOnline Access$$91397441.1 000777800 909CO $$ooai:library.usi.edu:777800$$pGLOBAL_SET 000777800 980__ $$aEBOOK 000777800 980__ $$aBIB 000777800 982__ $$aEbook 000777800 983__ $$aOnline 000777800 994__ $$a92$$bISE