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000777841 019__ $$a962303146$$a962325328$$a965145395$$a968904976$$a978677912$$a988783493
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000777841 0247_ $$a10.1007/978-981-10-2529-7$$2doi
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000777841 050_4 $$aRC78.7.C65
000777841 08204 $$a616.07/54$$223
000777841 1001_ $$aLaurent, Sophie.$$eauthor.
000777841 24510 $$aMRI contrast agents :$$bfrom molecules to particles /$$cSophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid, Robert N. Muller, Luce Vander Elst.
000777841 264_1 $$aSingapore :$$bSpringer Singapore :$$bImprint: Springer,$$c2017.
000777841 300__ $$a1 online resource (vii, 125 pages) :$$billustrations.
000777841 336__ $$atext$$btxt$$2rdacontent
000777841 337__ $$acomputer$$bc$$2rdamedia
000777841 338__ $$aonline resource$$bcr$$2rdacarrier
000777841 4901_ $$aSpringerBriefs in applied sciences and technology, Nanotheranostics
000777841 504__ $$aIncludes bibliographical references.
000777841 5050_ $$aNanomaterials in medicine -- Magnetic properties (diamagnetism, paramagnetism, ferromagnetism, ferrimagnetism, antiferromagnetism, superparamagnetism) -- Imaging probes -- Magnetic resonance imaging (MRI) -- Bases of MRI -- MRI contrast agents -- Paramagnetic gadolinium complexes -- Superparamagnetic iron oxide nanoparticles -- Synthesis of magnetic nanoparticles -- Stabilization of magnetic nanoparticles -- Physico-chemical characterization of nanoparticles -- MRI applications -- Conclusions.
000777841 506__ $$aAccess limited to authorized users.
000777841 520__ $$aThis book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc. .
000777841 650_0 $$aContrast media (Diagnostic imaging)
000777841 7001_ $$aHenoumont, Céline.$$eauthor.
000777841 7001_ $$aStanicki, Dimitri.$$eauthor.
000777841 7001_ $$aBoutry, Sébastien.$$eauthor.
000777841 7001_ $$aLipani, Estelle.$$eauthor.
000777841 7001_ $$aBelaid, Sarah.$$eauthor.
000777841 7001_ $$aMuller, Robert N.$$eauthor.
000777841 7001_ $$aVander Elst, Luce.$$eauthor.
000777841 77608 $$iPrint version:$$tMRI contrast agents.$$dSingapore : Springer, 2016, ©2017$$z9811025274$$z9789811025273$$w(OCoLC)954426001
000777841 830_0 $$aSpringerBriefs in applied sciences and technology.$$pNanotheranostics.
000777841 85280 $$bebk$$hSpringerLink
000777841 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-10-2529-7$$zOnline Access$$91397441.1
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