@article{777914,
      recid = {777914},
      author = {Pelaia, Girolamo, and Vatrella, Alessandro, and Maselli,  Rosario,},
      title = {Asthma : targeted biological therapies /},
      pages = {1 online resource},
      abstract = {This book focuses on the fundamentals of the use of  biologics in asthma, describing the rationale, principles,  mechanisms of action, and indications. It offers an  excellent balance between basic science and the analysis of  clinical trials, updating readers with new developments  that are changing the global scenario for targeted  biological anti-asthma therapies, especially with regard to  more severe disease. A range of therapies are considered,  from the humanized monoclonal anti-IgE antibody omalizumab,  widely approved as add-on treatment for inadequately  controlled disease, through to emerging biologics for which  evidence supportive of efficacy is accumulating, including  anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect  to emerge is the variability in individual response, which  suggests a need for characterization of different asthma  subtypes to permit the effective implementation of  phenotype-targeted treatments. This book will be of  interest for pulmonologists, clinical immunologists, and  physicians seeking sound information on these therapies,  but also for scientists and pharmacologists wishing to  enhance their knowledge of the therapeutic implications of  the cellular and molecular mechanisms that underlie severe,  uncontrolled asthma.},
      url = {http://library.usi.edu/record/777914},
      doi = {https://doi.org/10.1007/978-3-319-46007-9},
}