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Foreword; Acknowledgments; Contents; Contributors; Part I: Introduction; Chapter 1: Introduction; Chapter 2: Epidemiology and Natural History; Introduction; Incidence; Risk Factors; Progression of LM to LMM; Role of Genetics; Future Direction; Conclusion; References; Part II: Clinical and Pathologic Diagnosis; Chapter 3: Clinical Diagnosis; Introduction; Clinical Diagnosis; Patient Demographics; Location; Size; Morphology (Borders and Colors); ABCDE's of Melanoma; Deciding Whether and How to Biopsy; Wood's Lamp; Biopsy Techniques; Sampling Error; Conclusion; References.
Chapter 4: Role of Dermoscopy Introduction; Dermoscopy Technique; Anatomic Considerations of Lentigo Maligna Melanoma; Dermoscopic Features of LM/LMM; Progression Model of LMM; LM/LMM on Non-facial Skin; Dermoscopic Differential Diagnosis; Management of LM/LMM; Conclusion; References; Chapter 5: Pathologic Diagnosis; Introduction; Current Nomenclature; History: Hutchinson's Melanotic Freckle and Circumscribed Precancerous Melanosis of Dubreuilh; Histologic Diagnosis; Obtaining a Biopsy Specimen; Histologic Features; Ancillary Diagnostic Test; Immunohistochemistry.
Molecular Tests Differential Diagnosis; Melanocytic Hyperplasia of Sun-Damaged Skin; Solar Lentigo; Pigmented Actinic Keratosis; Lichen Planus-Like Keratosis; Pigmented Squamous Cell Carcinoma In Situ; Junctional Melanocytic Nevus; Future Considerations; Summary; References; Part III: Surgical Management; Chapter 6: Staged Excision Techniques; Introduction; Staged Excision Techniques; Square Procedure and Associated Variations; Spaghetti Technique and Associated Variations; Slow Mohs; Staged Excision with Radial Vertical Sections and Variations; Mapped Serial Excision.
Advantages and Disadvantages of Staged Excision Techniques Conclusion; References; Chapter 7: Mohs Surgery for Lentigo Maligna Melanoma; Introduction; History of Mohs Micrographic Surgery; The Process of Mohs Micrographic Surgery for Melanoma; Tumor Debulking for Melanoma Pathologic Staging; Immunohistochemical Stains for Melanoma; Highly Skilled Mohs Lab Necessary for Melanoma; Local Recurrence After Mohs Surgery; Indications for MMS; Advantages of Mohs Surgery; Detecting Melanoma Upstaging Prior to Reconstruction; Mohs Excision with Clear Histologic Margins Prior to Reconstrution.
Immediate Reconstruction After Clear Mohs Histologic Margins Mohs Surgery for Lentigo Maligna Melanoma: Controversies; Importance of Establishing a Standard Definition for a "Positive Margin" of Melanoma; Challenges for Widespread Use of Mohs Surgery for Melanoma; Conclusion; References; Chapter 8: Histologic Processing and Evaluation of Surgical Excision Specimens; Introduction; Standard Breadloaf; Technique; Advantages; Limitations; Margin Controlled Excision Techniques; Mohs Micrographic Surgery Using Frozen Sections; Technique; Advantages; Limitations; Staged Excision with Rush Permanent Sections with En Face Sectioning.
Chapter 4: Role of Dermoscopy Introduction; Dermoscopy Technique; Anatomic Considerations of Lentigo Maligna Melanoma; Dermoscopic Features of LM/LMM; Progression Model of LMM; LM/LMM on Non-facial Skin; Dermoscopic Differential Diagnosis; Management of LM/LMM; Conclusion; References; Chapter 5: Pathologic Diagnosis; Introduction; Current Nomenclature; History: Hutchinson's Melanotic Freckle and Circumscribed Precancerous Melanosis of Dubreuilh; Histologic Diagnosis; Obtaining a Biopsy Specimen; Histologic Features; Ancillary Diagnostic Test; Immunohistochemistry.
Molecular Tests Differential Diagnosis; Melanocytic Hyperplasia of Sun-Damaged Skin; Solar Lentigo; Pigmented Actinic Keratosis; Lichen Planus-Like Keratosis; Pigmented Squamous Cell Carcinoma In Situ; Junctional Melanocytic Nevus; Future Considerations; Summary; References; Part III: Surgical Management; Chapter 6: Staged Excision Techniques; Introduction; Staged Excision Techniques; Square Procedure and Associated Variations; Spaghetti Technique and Associated Variations; Slow Mohs; Staged Excision with Radial Vertical Sections and Variations; Mapped Serial Excision.
Advantages and Disadvantages of Staged Excision Techniques Conclusion; References; Chapter 7: Mohs Surgery for Lentigo Maligna Melanoma; Introduction; History of Mohs Micrographic Surgery; The Process of Mohs Micrographic Surgery for Melanoma; Tumor Debulking for Melanoma Pathologic Staging; Immunohistochemical Stains for Melanoma; Highly Skilled Mohs Lab Necessary for Melanoma; Local Recurrence After Mohs Surgery; Indications for MMS; Advantages of Mohs Surgery; Detecting Melanoma Upstaging Prior to Reconstruction; Mohs Excision with Clear Histologic Margins Prior to Reconstrution.
Immediate Reconstruction After Clear Mohs Histologic Margins Mohs Surgery for Lentigo Maligna Melanoma: Controversies; Importance of Establishing a Standard Definition for a "Positive Margin" of Melanoma; Challenges for Widespread Use of Mohs Surgery for Melanoma; Conclusion; References; Chapter 8: Histologic Processing and Evaluation of Surgical Excision Specimens; Introduction; Standard Breadloaf; Technique; Advantages; Limitations; Margin Controlled Excision Techniques; Mohs Micrographic Surgery Using Frozen Sections; Technique; Advantages; Limitations; Staged Excision with Rush Permanent Sections with En Face Sectioning.