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Preface; Contents; 1 Nanomedicine for Cancer Therapy; Abstract; 1 Introduction; 2 Conventional Therapy for Breast Cancer; 2.1 Limitation of Conventional Therapy; 3 Multiple Drug Resistance (MDR); 3.1 Drug Efflux and Decrease in Drug Uptake; 3.2 Alteration in Drug Target (Topoisomerase II); 3.3 Change in Detoxifying Enzyme Such Glutathione S-Transferase and Cytochrome P450; 3.4 Increase in DNA Repair; 3.5 Inhibition of Apoptosis by Disruption of Cell Signalling; 3.6 Therapy with Multiple Drug Delivery; 3.6.1 A: Combination of Two Drug Molecule.
3.6.2 B: Combination a Biologics and a Drug Molecule3.6.3 C: Drug Delivery Through Carrier or Nanomedicine; 4 Application of Nanoparticles in Cancer; 4.1 Types of Carriers (NPs) and Its Role in Nanomedicine for Cancer Therapy; 4.1.1 Organic Nanoparticle; 4.1.2 Inorganic Nanoparticle; 4.1.3 Metallic Nanoparticle; 4.1.4 Hybrid Nanoparticle; 4.1.5 Upconversion Nanoparticle; 5 Targeting or Delivery of NPs to the Cancer Cells; 5.1 Passive Targeting; 5.2 Active Targeting or Ligand-Mediated Targeting; 6 Role of Nanomedicine in Modern Day Cancer Therapy; 6.1 Gene Therapy.
6.1.1 DNA/SiRNA Based Gene Therapy6.2 Photodynamic Therapy; 6.2.1 Mechanism of Photodynamic Therapy; 6.2.2 Nanoparticle-Based Photodynamic Therapy; 6.3 Drug Resistance and Heat; 6.4 Therapy Based Thermal Ablation and Hyperthermia; 6.4.1 Types of Hyperthermia; 6.4.2 Heating Systems for Hyperthermia; 6.4.3 Electromagnetic Fields and Heating System/Equipment for Hyperthermia (Tableß6); 6.5 Nanoparticles Based Hyperthermia; 6.6 Nanoparticles Based Magnetic Hyperthermia; 6.7 Nano Radiofrequency Hyperthermia: NRFH; 6.8 Photothermal Therapy (PTT) with Nanoparticles Formulation.
6.8.1 Nanoparticles Mediated Photothermal Therapy6.8.2 Metallic Nanoparticles Mediated PTT; 6.8.3 Dye Encapsulated Nanoparticles Based Photothermal Therapy; 6.9 Nano High Intensity Focussed Ultrasound Hyperthermia (NHIFU); 7 Combinatorial Therapy with Hyperthermia; 7.1 Hyperthermia and Radiation; 7.2 Hyperthermia and Drugs; 7.3 Hyperthermia with Photosensitization; 8 Clinical Trials, Success, and Challenges; 9 Conclusion; 10 Challenges; 11 Prospective; References.
3.6.2 B: Combination a Biologics and a Drug Molecule3.6.3 C: Drug Delivery Through Carrier or Nanomedicine; 4 Application of Nanoparticles in Cancer; 4.1 Types of Carriers (NPs) and Its Role in Nanomedicine for Cancer Therapy; 4.1.1 Organic Nanoparticle; 4.1.2 Inorganic Nanoparticle; 4.1.3 Metallic Nanoparticle; 4.1.4 Hybrid Nanoparticle; 4.1.5 Upconversion Nanoparticle; 5 Targeting or Delivery of NPs to the Cancer Cells; 5.1 Passive Targeting; 5.2 Active Targeting or Ligand-Mediated Targeting; 6 Role of Nanomedicine in Modern Day Cancer Therapy; 6.1 Gene Therapy.
6.1.1 DNA/SiRNA Based Gene Therapy6.2 Photodynamic Therapy; 6.2.1 Mechanism of Photodynamic Therapy; 6.2.2 Nanoparticle-Based Photodynamic Therapy; 6.3 Drug Resistance and Heat; 6.4 Therapy Based Thermal Ablation and Hyperthermia; 6.4.1 Types of Hyperthermia; 6.4.2 Heating Systems for Hyperthermia; 6.4.3 Electromagnetic Fields and Heating System/Equipment for Hyperthermia (Tableß6); 6.5 Nanoparticles Based Hyperthermia; 6.6 Nanoparticles Based Magnetic Hyperthermia; 6.7 Nano Radiofrequency Hyperthermia: NRFH; 6.8 Photothermal Therapy (PTT) with Nanoparticles Formulation.
6.8.1 Nanoparticles Mediated Photothermal Therapy6.8.2 Metallic Nanoparticles Mediated PTT; 6.8.3 Dye Encapsulated Nanoparticles Based Photothermal Therapy; 6.9 Nano High Intensity Focussed Ultrasound Hyperthermia (NHIFU); 7 Combinatorial Therapy with Hyperthermia; 7.1 Hyperthermia and Radiation; 7.2 Hyperthermia and Drugs; 7.3 Hyperthermia with Photosensitization; 8 Clinical Trials, Success, and Challenges; 9 Conclusion; 10 Challenges; 11 Prospective; References.