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000778187 019__ $$a964931383$$a970785671$$a971038087$$a974651721
000778187 020__ $$a9783319459233$$q(electronic book)
000778187 020__ $$a3319459236$$q(electronic book)
000778187 020__ $$z9783319459219
000778187 020__ $$z331945921X
000778187 0247_ $$a10.1007/978-3-319-45923-3$$2doi
000778187 035__ $$aSP(OCoLC)ocn964585792
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000778187 049__ $$aISEA
000778187 050_4 $$aRM666.L57
000778187 08204 $$a616.89/5061$$223
000778187 24504 $$aThe science and practice of lithium therapy /$$cGin S. Malhi, Marc Masson, Frank Bellivier, editors.
000778187 260__ $$aCham, Switzerland :$$bSpringer,$$c2017.
000778187 300__ $$a1 online resource
000778187 336__ $$atext$$btxt$$2rdacontent
000778187 337__ $$acomputer$$bc$$2rdamedia
000778187 338__ $$aonline resource$$bcr$$2rdacarrier
000778187 347__ $$atext file$$bPDF$$2rda
000778187 504__ $$aIncludes bibliographical references and index.
000778187 5050_ $$aSection I: Science of Lithium: The Ion : Lithium -- Pharmacokinetics and pharmacodynamics of lithium -- Lithium : neurotransmission and cellular mechanisms pathways underlying neuroprogression in bipolar disorder -- Lithium on gene expression modulation -- Neuroimaging and lithium -- Conclusion: overview of potential mechanisms of action of lithium in bipolar disorder -- Section II: Practice of Lithium Therapy -- Introduction of lithium in Medicine and Psychiatry -- Lithium Response variability -- Lithium Response variability: Pharmacogenomics studies -- Lithium Response variability: Biomarkers -- Lithium in acute and maintenance treatment of bipolar disorders -- Lithium and suicide prevention -- Lithium in Bipolar disorders international guidelines -- Lithium and pregnancy -- Lithium in children and adolescents -- Short and mid-term side effects of lithium -- Lithium, kidneys, renal failure -- Lithium intoxication -- Discontinuation and re-use of lithium -- Conclusion : overview of indications and monitoring of lithium in bipolar disorders.
000778187 506__ $$aAccess limited to authorized users.
000778187 520__ $$aThis book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide.
000778187 588__ $$aDescription based on print  version record.
000778187 650_0 $$aLithium$$xTherapeutic use.
000778187 7001_ $$aMalhi, Gin S.
000778187 7001_ $$aMasson, Marc.
000778187 7001_ $$aBellivier, Frank.
000778187 77608 $$iPrint version:$$z331945921X$$z9783319459219$$w(OCoLC)954535813
000778187 852__ $$bebk
000778187 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-45923-3$$zOnline Access$$91397441.1
000778187 909CO $$ooai:library.usi.edu:778187$$pGLOBAL_SET
000778187 980__ $$aEBOOK
000778187 980__ $$aBIB
000778187 982__ $$aEbook
000778187 983__ $$aOnline
000778187 994__ $$a92$$bISE