Statistical analysis of proteomics, metabolomics, and lipidomics data using mass spectrometry / Susmita Datta, Bart J. A. Mertens, editors.
Datta, Susmita, editor.; Mertens, Bart J. A., editor.
2017
QP519.9.M3
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Title
Statistical analysis of proteomics, metabolomics, and lipidomics data using mass spectrometry / Susmita Datta, Bart J. A. Mertens, editors.
ISBN
9783319458090 (electronic book)
3319458094 (electronic book)
9783319458076
DOI
https://doi.org/10.1007/978-3-319-45809-0
Published
Cham, Switzerland : Springer, 2017.
Language
English
Description
1 online resource.
Item Number
10.1007/978-3-319-45809-0 doi
Call Number
QP519.9.M3
Dewey Decimal Classification
543/.65
Summary
This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies. Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types--as opposed to the familiar data structures in more classical genomics--but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results. Susmita Datta received her PhD in statistics from the University of Georgia. She is a tenured professor in the Department of Biostatistics at the University of Florida. Before joining the University of Florida she was a professor and a distinguished university scholar at the University of Louisville. She is a Fellow of the American Association for the Advancement of Science, American Statistical Association, and an elected member of the International Statistical Institute. She is past president of the Caucus for Women in Statistics, and she actively supports research and education for women in STEM fields. Bart Mertens received his PhD in statistical sciences from University College London, Department of Statistical Sciences, on statistical analysis methods for spectrometry data. He is currently Associate Professor at the Department of Medical Statistics and Bioinformatics of the Leiden University Medical Centre, where he has been working in both research and consulting for statistical analysis methodology with mass spectrometry proteomic data for more than 10 years.
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Digital File Characteristics
text file PDF
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed December 22, 2016).
Added Author
Datta, Susmita, editor.
Mertens, Bart J. A., editor.
Series
Frontiers in probability and the statistical sciences.
Available in Other Form
Print version: 9783319458076
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