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Table of Contents
Preface; Acknowledgments; Contents; 1: Development ofßtheßLung; 1.1 Genetic Control ofßtheßDevelopment; 1.2 Comparison ofßLung Development AcrossßSpecies; References; 2: Normal Lung; 2.1 Gross Morphology; 2.2 The Airways; 2.3 Lymphoreticular Tissue andßtheßImmune System ofßtheßLung; 2.4 Comparison ofßHuman Lung toßOther Species; References; 3: Pediatric Diseases; 3.1 Developmental andßInherited Lung Diseases; 3.1.1 Aplasia andßAcinar/Alveolar Dysgenesis; 3.1.2 Growth Retardation; 3.1.3 Vascular Malformations.
3.1.3.1 Alveolar Capillary Dysplasia with/Without Misalignment ofßPulmonary Veins3.1.3.2 Diffuse andßLocalized AV Anastomoses; 3.1.3.3 Anomalous Systemic Arterial Supply Including Sequestration; 3.1.4 Malformations ofßtheßAirway System; 3.1.4.1 Congenital Pulmonary Adenomatoid Malformation (CPAM, Formerly CCAM) Types I, II, andßIII; 3.1.4.2 Bronchogenic Cyst; 3.1.4.3 Immotile Cilia Syndrome; 3.1.5 Lung Pathology inßChromosomal Abnormalities; 3.1.6 Inborn Errors ofßMetabolism; 3.1.7 Cystic Fibrosis; 3.1.8 Neuroendocrine Cell Hyperplasia of Infancy (NEHI).
3.2 Pneumonia inßChildhood IncludingßNoninfectious Interstitial Pneumonias3.2.1 Chronic Pneumonia ofßInfancy (CPI); 3.2.2 Mendelson Syndrome inßChildren andßSilent Nocturnal Aspiration; References; 4: Edema; 4.1 Gross Morphology; 4.2 Histology; 4.3 High-Altitude Edema (HAPE); References; 5: Air Filling Diseases; 5.1 Atelectasis; 5.1.1 Gross Morphology; 5.1.2 Histology; 5.2 Emphysema; 5.2.1 Gross Morphology; 5.2.2 Histology; 5.3 Emphysema andßLung Function; 5.3.1 Factors Contributing toßEmphysema Development; References; 6: Airway Diseases; 6.1 Tracheitis andßBronchitis.
6.1.1 Gross Morphology6.1.2 Histology; 6.2 Bronchial Asthma; 6.2.1 Etiology; 6.2.2 Immune Mechanisms; 6.2.3 Gross Morphology; 6.2.4 Histology; 6.3 Bronchiolitis; 6.4 The Classification; References; 7: Smoking-Related Lung Diseases; 7.1 Langerhans Cell Histiocytosis; 7.1.1 Histology; 7.1.2 Molecular Biology; 7.1.3 Function ofßLH Cells; 7.1.4 Differential Diagnosis; 7.2 Respiratory Bronchiolitis: Interstitial Lung Disease (RBILD); 7.2.1 Histology; 7.3 Desquamative Interstitial Pneumonia (DIP); 7.3.1 Histology.
7.4 Smoking-Induced Interstitial Fibrosis (SRIF)/Respiratory Bronchiolitis-Associated Interstitial Lung Disease (RBILD)7.5 Chronic Obstructive Pulmonary Disease (COPD); 7.5.1 What Are theßMechanisms? Why Not Every Smoker Develops COPD?; References; 8: Pneumonia; 8.1 Alveolar Pneumonias (Lobar andßBronchopneumonia); 8.1.1 Clinical Symptoms ofßPneumonias; 8.1.2 Alveolar Pneumonias (Bronchopneumonia andßLobar Pneumonia; Adult andßChildhood); 8.1.2.1 Gross Morphology; 8.1.2.2 Variants ofßBronchopneumonias (Purulent Pneumonia (PN)).
3.1.3.1 Alveolar Capillary Dysplasia with/Without Misalignment ofßPulmonary Veins3.1.3.2 Diffuse andßLocalized AV Anastomoses; 3.1.3.3 Anomalous Systemic Arterial Supply Including Sequestration; 3.1.4 Malformations ofßtheßAirway System; 3.1.4.1 Congenital Pulmonary Adenomatoid Malformation (CPAM, Formerly CCAM) Types I, II, andßIII; 3.1.4.2 Bronchogenic Cyst; 3.1.4.3 Immotile Cilia Syndrome; 3.1.5 Lung Pathology inßChromosomal Abnormalities; 3.1.6 Inborn Errors ofßMetabolism; 3.1.7 Cystic Fibrosis; 3.1.8 Neuroendocrine Cell Hyperplasia of Infancy (NEHI).
3.2 Pneumonia inßChildhood IncludingßNoninfectious Interstitial Pneumonias3.2.1 Chronic Pneumonia ofßInfancy (CPI); 3.2.2 Mendelson Syndrome inßChildren andßSilent Nocturnal Aspiration; References; 4: Edema; 4.1 Gross Morphology; 4.2 Histology; 4.3 High-Altitude Edema (HAPE); References; 5: Air Filling Diseases; 5.1 Atelectasis; 5.1.1 Gross Morphology; 5.1.2 Histology; 5.2 Emphysema; 5.2.1 Gross Morphology; 5.2.2 Histology; 5.3 Emphysema andßLung Function; 5.3.1 Factors Contributing toßEmphysema Development; References; 6: Airway Diseases; 6.1 Tracheitis andßBronchitis.
6.1.1 Gross Morphology6.1.2 Histology; 6.2 Bronchial Asthma; 6.2.1 Etiology; 6.2.2 Immune Mechanisms; 6.2.3 Gross Morphology; 6.2.4 Histology; 6.3 Bronchiolitis; 6.4 The Classification; References; 7: Smoking-Related Lung Diseases; 7.1 Langerhans Cell Histiocytosis; 7.1.1 Histology; 7.1.2 Molecular Biology; 7.1.3 Function ofßLH Cells; 7.1.4 Differential Diagnosis; 7.2 Respiratory Bronchiolitis: Interstitial Lung Disease (RBILD); 7.2.1 Histology; 7.3 Desquamative Interstitial Pneumonia (DIP); 7.3.1 Histology.
7.4 Smoking-Induced Interstitial Fibrosis (SRIF)/Respiratory Bronchiolitis-Associated Interstitial Lung Disease (RBILD)7.5 Chronic Obstructive Pulmonary Disease (COPD); 7.5.1 What Are theßMechanisms? Why Not Every Smoker Develops COPD?; References; 8: Pneumonia; 8.1 Alveolar Pneumonias (Lobar andßBronchopneumonia); 8.1.1 Clinical Symptoms ofßPneumonias; 8.1.2 Alveolar Pneumonias (Bronchopneumonia andßLobar Pneumonia; Adult andßChildhood); 8.1.2.1 Gross Morphology; 8.1.2.2 Variants ofßBronchopneumonias (Purulent Pneumonia (PN)).