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Title
Cell therapy against cerebral stroke : comprehensive reviews for translational researches and clinical trials / Kiyohiro Houkin, Koji Abe, Satoshi Kuroda, editors.
ISBN
9784431560593 (electronic book)
4431560599 (electronic book)
9784431560579
Published
Tokyo, Japan : Springer, 2017.
Language
English
Description
1 online resource (x, 156 pages) : illustrations.
Item Number
10.1007/978-4-431-56059-3 doi
Call Number
RC388.5
Dewey Decimal Classification
616.8/106
Summary
This book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke. Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity. Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy. The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed January 19, 2017).
Available in Other Form
Print version: 9784431560579
Part I. Optimal Cell Sources
1. Bone Marrow-Derived Mononuclear Cells
2. Mesenchymal Stem Cells / Bone Marrow Stromal Cells
3. Neural Stem Cells / Neuronal Progenitor Cells
4. iPS Cells / iN
Part II. Translational Research
5. Cell Culture
6. Cell Dose, Timing and Route
7. Scaffold
8. Cell Tracking
9. Functional Bio-Imaging
Part III. Clinical Trials
10. Review of Previous Clinical Trials and Guideline of Cell Therapy
11. Bone Marrow-Derived Mononuclear Cells
12. Mesenchymal Stem Cells.