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000779111 24500 $$aNeurological regeneration /$$cPhuc Van Pham, editor.
000779111 260__ $$aCham :$$bSpringer,$$c2017.
000779111 300__ $$a1 online resource (266 pages).
000779111 336__ $$atext$$btxt$$2rdacontent
000779111 337__ $$acomputer$$bc$$2rdamedia
000779111 338__ $$aonline resource$$bcr$$2rdacarrier
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000779111 4901_ $$aStem cells in clinical applications
000779111 500__ $$a6.4 Mechanisms ofßAction ofßMesenchymal Stromal Cell-ƯBased \Therapies inßAnimal Models ofßNeonatal Hypoxia-Ischemia.
000779111 500__ $$aIncludes index.
000779111 504__ $$aIncludes bibliographical references and index.
000779111 5050_ $$aPreface; Contents; Biography; Chapter 1: Stem Cell Therapy inßNeurological andßNeurodegenerative Disease; 1.1 Introduction; 1.2 Types ofßStem Cells; 1.2.1 Embryonic Stem Cells; 1.2.2 Induced Pluripotent Stem Cells; 1.2.3 Tissue-Specific Stem Cells; 1.3 Stem Cell Therapy forßNeurological Diseases; 1.3.1 Alzheimer's Disease; 1.3.2 Parkinson's Disease; 1.3.3 Huntington's Disease; 1.3.4 Cancer; 1.4 Conclusion; References; Chapter 2: Stem Cell Therapy inßTraumatic Brain Injury; 2.1 Introduction; 2.2 Neuropathology ofßTraumatic Brain Injury; 2.2.1 Primary Injury After Traumatic Brain Injury.
000779111 5058_ $$a2.2.2 Secondary Injury After Traumatic Brain Injury2.3 Current Pharmacotherapy forßTraumatic Brain Injury; 2.4 Stem Cell Therapy inßTraumatic Brain Injury; 2.4.1 Transplantation ofßExogenous Stem Cells inßTraumatic Brain Injury; 2.4.2 Stimulation ofßEndogenous Neural Precursor Cells inßTraumatic Brain Injury; 2.5 Bench toßBedside Translation ofßStem Cell Therapy inßTraumatic Brain Injury; 2.6 Conclusion; References; Chapter 3: Stem Cells inßAlzheimer's Disease Therapy; 3.1 Introduction; 3.2 Pathogenesis ofßAlzheimer's Disease andßDrug Treatment; 3.3 Animal Models inßAD Therapy withßStem Cells.
000779111 5058_ $$a3.4 Stem Cells asßaßModel toßStudy AD3.5 The Use ofßStem Cells inßAD Therapy; 3.6 Conclusion; References; Chapter 4: Stem Cell-Based Approaches forßTreatment ofßGlioblastoma; 4.1 Introduction; 4.2 Glioblastoma; 4.2.1 Epidemiology; 4.2.2 Genetic Background; 4.3 Current Treatment Options forßGlioblastoma; 4.3.1 Standard ofßCare; 4.3.2 Molecular Treatment Strategies; 4.3.3 Limitations ofßAvailable Treatments; 4.4 Application ofßStem Cells toßGlioblastoma Therapy; 4.4.1 Rationale forßStem Cell-Based Therapies; 4.4.2 Application ofßStem Cells forßTreatment ofßGlioblastoma; 4.4.3 Immunotoxins.
000779111 5058_ $$a4.4.4 Suicide Gene Fusion4.4.5 Oncolytic Viruses; 4.4.6 miRNAs; 4.5 Future Directions; 4.5.1 Limitations andßPotential Solutions; 4.5.2 Ethical Concerns; 4.5.3 Concluding Remarks; References; Chapter 5: Stem Cell-Based Therapies forßParkinson's Disease; 5.1 Introduction; 5.2 Grafts ofßHuman Fetal Ventral Mesencephalic Tissue; 5.3 Stem Cell Properties andßRequirements forßTheir Application inßCRT forßPD; 5.4 Multipotent Stem Cells; 5.4.1 Human Neural Stem Cells; 5.4.2 Human Mesenchymal Stem Cells; 5.4.3 Human Pluripotent Stem Cells; 5.4.4 Human Embryonic Stem Cells.
000779111 5058_ $$a5.4.5 Human Parthenogenetic Embryonic Stem Cells5.4.6 Human Induced Pluripotent Stem Cells; 5.5 Conclusions andßFuture Directions; References; Chapter 6: Mesenchymal Stromal Cell Therapy forßNeonatal Hypoxic-Ischemic Encephalopathy; 6.1 Introduction; 6.2 Mesenchymal Stromal Cells; 6.3 The Therapeutic Efficacy ofßMesenchymal Stromal Cells inßPreclinical Animal Models ofßNeonatal Hypoxia-Ischemia; 6.3.1 Mesenchymal Stromal Cells fromßAdult Tissues; 6.3.2 Mesenchymal Stromal Cells fromßNeonatal Tissues.
000779111 506__ $$aAccess limited to authorized users.
000779111 520__ $$aThis invaluable resource explores the regenerative potential of stem cells in the nervous system, with a focus on clinical applications. The expertly authored chapters discuss cell-based therapies for spinal cord injury and regeneration, traumatic brain injury, glioblastoma, Parkinson's Disease, ischemic stroke, cell banking, human embryonic stem cells and related concerns, harvesting of adipose tissue, and more. These topics are contextualized within a discussion of future directions of these therapies. Neurological Regeneration, part of Springerℓ́ℓs Stem Cells in Clinical Applications series, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, neurology, regenerative medicine or tissue engineering.
000779111 588__ $$aDescription based on print  version record.
000779111 650_0 $$aStem cells$$xTherapeutic use.
000779111 650_0 $$aNervous system$$xRegeneration.
000779111 7001_ $$aPham, Phuc Van,$$eeditor.
000779111 77608 $$iPrint version:$$aPham, Phuc Van.$$tNeurological Regeneration.$$dCham : Springer International Publishing, ©2017$$z9783319337197
000779111 830_0 $$aStem cells in clinical applications.
000779111 852__ $$bebk
000779111 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-33720-3$$zOnline Access$$91397441.1
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000779111 980__ $$aEBOOK
000779111 980__ $$aBIB
000779111 982__ $$aEbook
000779111 983__ $$aOnline
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