000779123 000__ 05651cam\a2200553Ii\4500 000779123 001__ 779123 000779123 005__ 20230306142912.0 000779123 006__ m\\\\\o\\d\\\\\\\\ 000779123 007__ cr\nn\nnnunnun 000779123 008__ 170121t20172017sz\a\\\\ob\\\\000\0\eng\d 000779123 019__ $$a969876156$$a974650548$$a981034994$$a981816974 000779123 020__ $$a9783319496740$$q(electronic book) 000779123 020__ $$a3319496743$$q(electronic book) 000779123 020__ $$z9783319496726 000779123 020__ $$z3319496727 000779123 0247_ $$a10.1007/978-3-319-49674-0$$2doi 000779123 035__ $$aSP(OCoLC)ocn969646421 000779123 035__ $$aSP(OCoLC)969646421$$z(OCoLC)969876156$$z(OCoLC)974650548$$z(OCoLC)981034994$$z(OCoLC)981816974 000779123 040__ $$aEBLCP$$beng$$erda$$epn$$cEBLCP$$dN$T$$dGW5XE$$dMMU$$dOCLCO$$dYDX$$dIDEBK$$dUAB$$dCOO$$dOCLCF$$dOCLCQ$$dOCLCO$$dUPM$$dCCO$$dSTF$$dMERUC$$dVT2$$dIOG 000779123 049__ $$aISEA 000779123 050_4 $$aQP552.C6 000779123 050_4 $$aQH301-705 000779123 066__ $$c(S 000779123 08204 $$a572/.67$$223 000779123 08204 $$a570 000779123 24500 $$aFibrous proteins :$$bstructures and mechanisms /$$cDavid A.D. Parry, John M. Squire, editors. 000779123 264_1 $$aCham :$$bSpringer,$$c[2017] 000779123 264_4 $$c©2014 000779123 300__ $$a1 online resource (630 pages) :$$billustrations. 000779123 336__ $$atext$$btxt$$2rdacontent 000779123 337__ $$acomputer$$bc$$2rdamedia 000779123 338__ $$aonline resource$$bcr$$2rdacarrier 000779123 347__ $$atext file$$bPDF$$2rda 000779123 4901_ $$aSubcellular biochemistry,$$x0306-0225 ;$$vvolume 82 000779123 504__ $$aIncludes bibliographical references. 000779123 5050_ $$aFibrous protein structures: hierarchy, history and heroes / John M. Squire, David A.D. Parry -- Coiled-coil design: updated and upgraded / Derek N. Woolfson -- Functional and structural roles of coiled coils / Marcus D. Hartmann -- The structure and topology of [alpha]-helical coiled coils / Andrei N. Lupas, Jens Bassler, Stanislaw Dunin-Horkawicz -- Structural transition of trichocyte keratin intermediate filaments during development in the hair follicle / R.D. Bruce Fraser, David A.D. Parry -- Crystallographic studies of intermediate filament proteins / Dmytro Guzenko, Anastasia A. Chernyatina, Sergei V. Strelkov -- Lessons from animal models of cytoplasmic intermediate filament proteins / Jamal-Eddine Bouameur, Thomas M. Magin -- Filamentous structure of hard [beta]-keratins in the epidermal appendages of birds and reptiles / R.D. Bruce Fraser, David A.D. Parry -- Tropomyosin structure, function, and interactions: a dynamic regulator / Sarah E. Hitchcock-DeGregori, Bipasha Barua -- Titin and nebulin in thick and thin filament length regulation / Larissa Tskhovrebova, John Trinick -- Myosin and actin filaments in muscle: structures and interactions / John M. Squire, Danielle M. Paul, Edward P. Morris -- Dystrophin and spectrin, two highly dissimilar sisters of the same family / Olivier Delalande, Aleksander Czogalla, Jean-Fraṅois Hubert, Aleksander Sikorski [and others] -- Fibrin formation, structure and properties / John W. Weisel, Rustem I. Litvinov -- Fibrillar collagens / Jordi Bella, David J.S. Hulmes -- Recombinant structural proteins and their use in future materials / Tara D. Sutherland, Trevor D. Rapson, Mickey G. Huson, Jeffrey S. Church -- Properties of engineered and fabricated silks / Gregor Lang, Heike Herold, Thomas Scheibel -- Biomaterials made from coiled-coil peptides / Vincent Conticello, Spencer Hughes, Charles Modlin -- Bioengineered collagens / Barbara Brodsky, John A.M. Ramshaw. 000779123 506__ $$aAccess limited to authorized users. 000779123 520__ $$a"This book provides the readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease. The importance of the [alpha]-helical coiled coil, a conformational motif based on the heptad repeat in the amino acid sequence of all [alpha]-fibrous proteins (and parts of some globular proteins) is underlined by three Chapters devoted to its design, structure, function and topology. Specific proteins covered in the text and which depend on the coiled coil for their structure and function, include the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and members of the spectrin superfamily. Also described are fibrous proteins based on the [beta]-pleated sheet and collagen conformations. Recombinant structural proteins, especially of silk and collagen, are discussed in the context of developing new biomaterials with varied applications. Established researchers and postgraduate students in the fields of protein chemistry, biochemistry and structural biophysics will find Fibrous Proteins: Structures and Mechanisms to be an invaluable collection of topical reviews that describe the basic advances made in the field of fibrous proteins over the past decade. This book, written by recognized authorities in the field, provides a clear account of the current status of fibrous protein research and, in addition, establishes the basis for deciding the most appropriate directions for future activity, including the applications of protein engineering and the commercial exploitation of new biomaterials. 000779123 588__ $$aOnline resource; title from resource home page (SpringerLink, viewed January 31, 2017). 000779123 650_0 $$aProteins. 000779123 650_0 $$aCollagen. 000779123 7001_ $$aParry, D. A. D.,$$eeditor. 000779123 7001_ $$aSquire, John,$$d1945-$$eeditor. 000779123 77608 $$iPrint version:$$tFibrous proteins: structures and mechanisms.$$dCham : Springer, [2017]$$z9783319496726$$w(OCoLC)961800132 000779123 830_0 $$aSub-cellular biochemistry ;$$vv. 82. 000779123 852__ $$bebk 000779123 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-49674-0$$zOnline Access$$91397441.1 000779123 909CO $$ooai:library.usi.edu:779123$$pGLOBAL_SET 000779123 980__ $$aEBOOK 000779123 980__ $$aBIB 000779123 982__ $$aEbook 000779123 983__ $$aOnline 000779123 994__ $$a92$$bISE