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Preface; Contents; Phytochemistry of Cannabis sativa L.; 1 Introduction; 2 Nomenclature; 2.1 Botanical Nomenclature; 2.2 Common Names; 2.3 Definition of Cannabis; 3 Cultivation of Cannabis sativa; 3.1 Outdoor Cultivation; 3.2 Indoor Cultivation; 3.2.1 Propagation Through Seeds; 3.2.2 Propagation Through Vegetative Cuttings; 3.2.3 Micropropagation; 3.3 Harvesting, Processing, and Storage of Cannabis sativa Biomass; 4 Chemotaxonomy of Cannabis sativa; 5 Biosynthesis of Phytocannabinoids; 6 Constituents of Cannabis sativa; 6.1 Cannabinoids
6.1.1 (-)-Delta9-trans-Tetrahydrocannabinol (Delta9-THC) Type6.1.2 (-)-Delta8-trans-Tetrahydrocannabinol (Delta8-THC) Type; 6.1.3 Cannabigerol (CBG) Type; 6.1.4 Cannabichromene (CBC) Type; 6.1.5 Cannabidiol (CBD) Type; 6.1.6 Cannabinodiol (CBND) Type; 6.1.7 Cannabielsoin (CBE) Type; 6.1.8 Cannabicyclol (CBL) Type; 6.1.9 Cannabinol (CBN) Type; 6.1.10 Cannabitriol (CBT) Type; 6.1.11 Miscellaneous Types; 6.2 Non-Cannabinoid Constituents; 7 Analysis of Cannabinoids in Cannabis sativa and Its Preparations; References; Synthesis of Phytocannabinoids; 1 Introduction; 2 Early Approaches
3 Stereospecific Approaches4 Enantioselective Approaches; 5 Conclusion; References; Molecular Pharmacology of Phytocannabinoids; 1 Introduction; 2 Delta9-trans-Tetrahydrocannabinol; 2.1 Activity at Cannabinoid Receptors; 2.2 Cannabinoid Receptor Independent Activity; 3 Delta9-Tetrahydrocannabivarin; 3.1 Activity at Cannabinoid Receptors; 3.2 Cannabinoid Receptor Independent Activity; 4 Cannabinol; 4.1 Activity at Cannabinoid Receptors; 4.2 Cannabinoid Receptor Independent Activity; 5 Cannabidiol; 5.1 Activity at Cannabinoid Receptors; 5.2 Cannabinoid Receptor Independent Activity
6 Cannabidivarin6.1 Activity at Cannabinoid Receptors; 6.2 Cannabinoid Receptor Independent Activity; 7 Cannabigerol; 7.1 Activity at Cannabinoid Receptors; 7.2 Cannabinoid Receptor Independent Activity; 8 Cannabichromene; 8.1 Activity at Cannabinoid Receptors; 8.2 Cannabinoid Receptor Independent Activity; 9 Conclusions; References; Molecular Targets of the Phytocannabinoids: A Complex Picture; 1 Introduction; 2 Pharmacology of Selected Phytocannabinoids; 2.1 Abundant Cannabinoid Constituents of Cannabis sativa; 2.1.1 Delta9-Tetrahydrocannabinol (Delta9-THC)
2.1.2 Delta8-Tetrahydrocannabinol (Delta8-THC)2.1.3 Cannabinol (CBN); 2.1.4 Cannabidiol (CBD); 2.1.5 Cannabigerol (CBG); 2.1.6 Cannabichromene (CBC); 2.1.7 Delta9-Tetrahydrocannabivarin (Delta9-THCV); 2.1.8 Cannabivarin (CBV); 2.1.9 Cannabidivarin (CBDV); 2.2 Less Abundant Cannabinoid Constituents of Cannabis sativa; 2.2.1 Cannabinodiol (CBND); 2.2.2 Cannabielsoin (CBE); 2.2.3 Cannabicyclol (CBL); 2.2.4 Cannabitriol (CBT); 3 Molecular Targets of Phytocannabinoids; 3.1 G-Protein Coupled Receptors; 3.2 Beyond GPCRs: PPARs, GlyR, and TRP Channels
6.1.1 (-)-Delta9-trans-Tetrahydrocannabinol (Delta9-THC) Type6.1.2 (-)-Delta8-trans-Tetrahydrocannabinol (Delta8-THC) Type; 6.1.3 Cannabigerol (CBG) Type; 6.1.4 Cannabichromene (CBC) Type; 6.1.5 Cannabidiol (CBD) Type; 6.1.6 Cannabinodiol (CBND) Type; 6.1.7 Cannabielsoin (CBE) Type; 6.1.8 Cannabicyclol (CBL) Type; 6.1.9 Cannabinol (CBN) Type; 6.1.10 Cannabitriol (CBT) Type; 6.1.11 Miscellaneous Types; 6.2 Non-Cannabinoid Constituents; 7 Analysis of Cannabinoids in Cannabis sativa and Its Preparations; References; Synthesis of Phytocannabinoids; 1 Introduction; 2 Early Approaches
3 Stereospecific Approaches4 Enantioselective Approaches; 5 Conclusion; References; Molecular Pharmacology of Phytocannabinoids; 1 Introduction; 2 Delta9-trans-Tetrahydrocannabinol; 2.1 Activity at Cannabinoid Receptors; 2.2 Cannabinoid Receptor Independent Activity; 3 Delta9-Tetrahydrocannabivarin; 3.1 Activity at Cannabinoid Receptors; 3.2 Cannabinoid Receptor Independent Activity; 4 Cannabinol; 4.1 Activity at Cannabinoid Receptors; 4.2 Cannabinoid Receptor Independent Activity; 5 Cannabidiol; 5.1 Activity at Cannabinoid Receptors; 5.2 Cannabinoid Receptor Independent Activity
6 Cannabidivarin6.1 Activity at Cannabinoid Receptors; 6.2 Cannabinoid Receptor Independent Activity; 7 Cannabigerol; 7.1 Activity at Cannabinoid Receptors; 7.2 Cannabinoid Receptor Independent Activity; 8 Cannabichromene; 8.1 Activity at Cannabinoid Receptors; 8.2 Cannabinoid Receptor Independent Activity; 9 Conclusions; References; Molecular Targets of the Phytocannabinoids: A Complex Picture; 1 Introduction; 2 Pharmacology of Selected Phytocannabinoids; 2.1 Abundant Cannabinoid Constituents of Cannabis sativa; 2.1.1 Delta9-Tetrahydrocannabinol (Delta9-THC)
2.1.2 Delta8-Tetrahydrocannabinol (Delta8-THC)2.1.3 Cannabinol (CBN); 2.1.4 Cannabidiol (CBD); 2.1.5 Cannabigerol (CBG); 2.1.6 Cannabichromene (CBC); 2.1.7 Delta9-Tetrahydrocannabivarin (Delta9-THCV); 2.1.8 Cannabivarin (CBV); 2.1.9 Cannabidivarin (CBDV); 2.2 Less Abundant Cannabinoid Constituents of Cannabis sativa; 2.2.1 Cannabinodiol (CBND); 2.2.2 Cannabielsoin (CBE); 2.2.3 Cannabicyclol (CBL); 2.2.4 Cannabitriol (CBT); 3 Molecular Targets of Phytocannabinoids; 3.1 G-Protein Coupled Receptors; 3.2 Beyond GPCRs: PPARs, GlyR, and TRP Channels