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000779572 019__ $$a974445479$$a974565858$$a981773972
000779572 020__ $$a9783319477541$$q(electronic book)
000779572 020__ $$a3319477544$$q(electronic book)
000779572 020__ $$z9783319477527
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000779572 0247_ $$a10.1007/978-3-319-47754-1$$2doi
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000779572 08204 $$a615.9/07$$223
000779572 24500 $$aModelling the toxicity of nanoparticles /$$cLang Tran, Miguel A. Bañares, Robert Rallo, editors.
000779572 264_1 $$aCham, Switzerland :$$bSpringer,$$c2017.
000779572 300__ $$a1 online resource (xvii, 352 pages) :$$billustrations.
000779572 336__ $$atext$$btxt$$2rdacontent
000779572 337__ $$acomputer$$bc$$2rdamedia
000779572 338__ $$aonline resource$$bcr$$2rdacarrier
000779572 347__ $$atext file$$bPDF$$2rda
000779572 4901_ $$aAdvances in experimental medicine and biology,$$x0065-2598 ;$$vvolume 947
000779572 500__ $$aIncludes index.
000779572 5050_ $$aEngineered Nanoparticles ? Their physico-chemical characteristics and how to measure them -- Measurement -- The Life-Cycle of Engineered Nanoparticles -- From Dose to Response ? In vivo Nanoparticle Processing and Potential Toxicity -- From Dose to Response ? Literature review od (Q)SAR Modelling of Nanomaterial Toxicity -- Systems biology to support nanomaterial grouping -- Multiscale modelling of bionano interface -- Biological Surface Adsorption Index of Nanomaterials -- Modeling Surface Interactions of Nanomaterials with Biomolecules -- Case study I -- An integrated data-driven strategy for safe-by-design nanoparticles: The FP7 MODERN Project -- Case study II -- Compilation of Data and Modeling of Nanoparticle Interactions and Toxicity and in the European NanoPUZZLES Project -- Case study III ? The construction of a nanotoxicity database: the MOD-ENP-TOX experience.
000779572 506__ $$aAccess limited to authorized users.
000779572 520__ $$aIn todayℓ́ℓs nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.
000779572 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed February 15, 2017).
000779572 650_0 $$aNanoparticles$$xToxicity testing.
000779572 650_0 $$aAlternative toxicity testing.
000779572 7001_ $$aTran, Lang,$$eeditor.
000779572 7001_ $$aBañares, Miguel A.,$$eeditor.
000779572 7001_ $$aRallo, Robert,$$eeditor.
000779572 77608 $$iPrint version:$$z3319477528$$z9783319477527$$w(OCoLC)959033551
000779572 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 947.
000779572 852__ $$bebk
000779572 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-47754-1$$zOnline Access$$91397441.1
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