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000779635 019__ $$a973086296$$a973302220$$a973379379$$a973523868$$a973764175$$a973806913
000779635 020__ $$a9783319500447$$q(electronic book)
000779635 020__ $$a3319500449$$q(electronic book)
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000779635 08204 $$a572.8/293$$223
000779635 24500 $$aSUMO regulation of cellular processes /$$cVan G. Wilson, editor.
000779635 250__ $$aSecond edition.
000779635 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2017]
000779635 264_4 $$c©2017
000779635 300__ $$a1 online resource (viii, 415 pages) :$$billustrations.
000779635 336__ $$atext$$btxt$$2rdacontent
000779635 336__ $$astill image$$bsti$$2rdacontent
000779635 337__ $$acomputer$$bc$$2rdamedia
000779635 338__ $$aonline resource$$bcr$$2rdacarrier
000779635 4901_ $$aAdvances in experimental medicine and biology,$$x2214-8019 ;$$vvolume 963
000779635 504__ $$aIncludes bibliographical references and index.
000779635 5050_ $$aIntroduction to Sumoylation / Van G. Wilson -- Molecular function. Roles of sumoylation in mRNA processing and metabolism / Patricia Richard, Vasupradha Vethantham, James L. Manley -- SUMO and chromatin remodeling / David Wotton, Lucy F. Pemberton, Jacqueline Merrill-Schools -- Functions of SUMO in the maintenance of genome stability / Nicola Zilio, Karolin Eifler-Olivi, Helle D. Ulrich -- Regulation of cellular processes by SUMO: understudied topics / Jorrit M. Enserink -- The molecular interface between the SUMO and ubiquitin systems / Jeff L. Staudinger -- SUMO and nucleocytoplasmic transport / Christopher Ptak, Richard W. Wozniak -- SUMO modification of ion channels / Mark Benson, Jorge A. Iñiguez-lluhí, Jeffrey Martens -- The roles of SUMO in metabolic regulation / Elena Kamynina, Patrick J. Stover -- Cell growth regulation. The SUMO pathway in mitosis / Debaditya Mukhopadhyay, Mary Dasso -- Wrestling with chromosomes: the roles of SUMO during meiosis / Amanda C. Nottke, Hyun-Min Kim, Monica P. Colaiácovo -- Sumoylation in development and differentiation / Adeline F. Deyrieux, Van G. Wilson -- The role of sumoylation in senescence / Lyndee L. Scurr, Sebastian Haferkamp, Helen Rizos -- Regulation of plant cellular and organismal development by SUMO / Nabil Elrouby -- SUMO in drosophila development / Joseph Cao, Albert J. Courey -- Diseases. Sumoylation: implications for neurodegenerative diseases / Dina B. Anderson, Camila A. Zanella, Jeremy M. Henley, Helena Cimarosti -- Sumoylation and its contribution to cancer / Jason S. Lee, Hee June Choi, Sung Hee Baek -- Sumoylation modulates the susceptibility to type 1 diabetes / Jing Zhang, Zhishui Chen, Zhiguang Zhou, Ping Yang, Cong-Yi Wang -- Sumoylation in craniofacial disorders / Erwin Pauws, Philip Stanier -- Coordination of cellular localization-dependent effects of sumoylation in regulating cardiovascular and neurological diseases / Jun-ichi Abe, Uday G. Sandhu, Nguyet Minh Hoang, Manoj Thangam [and others] -- Sumoylation as an integral mechanism in bacterial infection and disease progression / Chittur V. Srikanth, Smriti Verma.
000779635 506__ $$aAccess limited to authorized users.
000779635 520__ $$a"This is the second edition of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule. Individual chapters explore the biochemistry, molecular biology, and cell biology of the sumoylation system and its substrate proteins. The book is divided into three themed parts: Molecular Functions (I), Cell Growth Regulation (II), and Diseases (III). Parts I and II focus on the contribution of sumoylation to cellular activities in both the nuclear and cytoplasmic compartments. The nuclear activities covered include nucleic acid metabolism (both RNA and DNA), chromosome structure and replication, and nucleocytoplasmic transport. Cytoplasmic processes presented include regulation of membrane ion channels, general metabolism, and apoptotic signalling. Topics in Part III include the role of sumoylation in developmental abnormalities (craniofacial and cardiovascular), diabetes, neurodegenerative diseases, cancer, and infections with viruses and bacteria. Each of the corresponding chapter authors is an active researcher who has made significant contributions to understanding sumoylation. This second edition provides updates and revisions to most of the original chapters plus adds six new chapters to address important developing areas of sumoylation research"--Publisher's description.
000779635 588__ $$aDescription based on online resource; title from pdf title page (Springerlink, viewed February 28, 2017).
000779635 650_0 $$aPost-translational modification.
000779635 650_0 $$aProteins$$xSynthesis.
000779635 650_0 $$aUbiquitin.
000779635 7001_ $$aWilson, Van Gene.
000779635 77608 $$iPrint version:$$tSUMO regulation of cellular processes.$$b2nd ed.$$dCham : Springer, 2017$$z9783319500447
000779635 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 963.
000779635 852__ $$bebk
000779635 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-50044-7$$zOnline Access$$91397441.1
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000779635 983__ $$aOnline
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