000779649 000__ 04810cam\a2200505Ia\4500 000779649 001__ 779649 000779649 005__ 20230306143030.0 000779649 006__ m\\\\\o\\d\\\\\\\\ 000779649 007__ cr\nn\nnnunnun 000779649 008__ 170218s2017\\\\sz\\\\\\o\\\\\000\0\eng\d 000779649 020__ $$a9783319497129$$q(electronic book) 000779649 020__ $$a331949712X$$q(electronic book) 000779649 020__ $$z9783319497112 000779649 035__ $$aSP(OCoLC)ocn973188151 000779649 035__ $$aSP(OCoLC)973188151 000779649 040__ $$aEBLCP$$beng$$cEBLCP$$dOCLCO$$dGW5XE$$dN$T$$dYDX$$dOCLCF$$dSTF$$dIOG 000779649 049__ $$aISEA 000779649 050_4 $$aRS403$$b.P76 2017eb 000779649 08204 $$a547$$223 000779649 24500 $$aProgress in the chemistry of organic natural products.$$nVolume 105$$cA. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, editors. 000779649 260__ $$aCham :$$bSpringer,$$c2017. 000779649 300__ $$a1 online resource (221 pages) 000779649 4901_ $$aProgress in the chemistry of organic natural products ;$$vv.105 000779649 500__ $$a4.1.4 Rearranged Ibogamine/Coronaridine Alkaloids 000779649 5050_ $$aXanthine Alkaloids: Occurrence, Biosynthesis, and Function in Plants; 1 Introduction; 2 Occurrence of Xanthine Alkaloids in the Plant Kingdom; 2.1 Ericales (Tea and Related Species); 2.2 Gentianales (Coffee and Related Species); 2.3 Aquifoliales (Maté and Related Species); 2.4 Malvales (Cacao, Cola, and Related Species); 2.5 Sapindales (Guaran, Citrus, and Related Plants); 2.6 Other Species; 3 Biosynthesis of Xanthine Alkaloids; 3.1 A Brief History of the Elucidation of the Biosynthesis Pathways; 3.2 Caffeine Biosynthesis Pathways from Xanthosine; 3.2.1 Formation of 7-Methylxanthine 000779649 5058_ $$aFeeding ExperimentsEnzyme Studies; Genes and Proteins; 3.2.2 Conversion of 7-Methylxanthine to Caffeine via Theobromine; Feeding Experiments; Enzyme Studies; Genes and Proteins; 3.2.3 Evolutionary Relationship of the Caffeine Synthase Family Proteins; 3.3 Pathways that Supply Xanthosine for Caffeine Biosynthesis; 3.3.1 De Novo Route; 3.3.2 AMP Route; 3.3.3 SAM Cycle Route; 3.3.4 NAD Route; 3.3.5 GMP Route; 3.4 Localization of Xanthine Alkaloid Biosynthesis; 3.4.1 Organs and Tissues; Camellia; Coffea; Theobroma; Maté and Guaran; 3.4.2 Subcellular Accumulation of Xanthine Alkaloids 000779649 5058_ $$a3.4.3 Subcellular Localization of Caffeine Biosynthesis EnzymesCaffeine Synthase; Enzymes Involved in the de Novo Route; Enzymes Involved in the AMP Route; Enzymes Involved in the SAM Route; 3.4.4 Subcellular Localization and Transport of Intermediates; 3.5 Regulation of Caffeine Biosynthesis; 4 Metabolism of Xanthine Alkaloids; 4.1 Methyluric Acid Biosynthesis; 4.2 Biodegradation and Inter-conversion of Xanthine Alkaloids; 4.2.1 The Major Pathway of Caffeine Degradation; 4.2.2 Conventional Purine Catabolic Pathways in Plants; 4.2.3 Diversity of Xanthine Alkaloid Metabolism in Plants; Coffea 000779649 5058_ $$aTea4.2.4 Xanthine Alkaloid Metabolism in Bacteria and Animals; Bacteria; Animals; 5 Ecological Roles of Xanthine Alkaloids; 5.1 Allelopathic Function Theory; 5.1.1 Effect of Xanthine Alkaloids on Germination and Growth of Plants; 5.1.2 Effect of Xanthine Alkaloids on Proliferation of Plant Cells; 5.1.3 Effect of Xanthine Alkaloids on Plant Metabolism; 5.1.4 Effect of Caffeine on Protein Expression Profiles; 5.1.5 Allelopathy in Natural Ecosystems; 5.2 Chemical Defense Theory; 5.2.1 Chemical Defense Against Microorganisms and Animals 000779649 5058_ $$a5.2.2 Proof of the Chemical Defense Theory Demonstrated with Transgenic Plants6 Biotechnology of Xanthine Alkaloids; 6.1 Decaffeinated Coffee and Tea Plants; 6.2 Caffeine-Producing Transgenic Plants; 6.2.1 Antiherbivore Activity; 6.2.2 Antipathogen Activity; 7 Summary and Perspectives; References; The Iboga Alkaloids; 1 Introduction; 2 Biosynthesis; 3 Structural Elucidation and Reactivity; 4 New Molecules; 4.1 Monomers; 4.1.1 Ibogamine and Coronaridine Derivatives; 4.1.2 3-Alkyl- or 3-Oxo-ibogamine/-coronaridine Derivatives; 4.1.3 5- and/or 6-Oxo-ibogamine/-coronaridine Derivatives 000779649 506__ $$aAccess limited to authorized users. 000779649 588__ $$aDescription based upon print version of record. 000779649 588__ $$aDescription based on print version record. 000779649 650_0 $$aChemistry, Organic. 000779649 650_0 $$aPharmaceutical chemistry. 000779649 650_0 $$aClinical biochemistry. 000779649 7001_ $$aKinghorn, A. Douglas. 000779649 7001_ $$aFalk, Heinz,$$d1939- 000779649 7001_ $$aGibbons, Simon$$c(Professor of medicinal phytochemistry) 000779649 7001_ $$aKobayashi, Jun'ichi. 000779649 77608 $$iPrint version:$$tProgress in the chemistry of organic natural products. Volume 105.$$dCham : Springer, 2017$$z9783319497129 000779649 830_0 $$aFortschritte der Chemie organischer Naturstoffe ;$$vv. 105. 000779649 852__ $$bebk 000779649 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-49712-9$$zOnline Access$$91397441.1 000779649 909CO $$ooai:library.usi.edu:779649$$pGLOBAL_SET 000779649 980__ $$aEBOOK 000779649 980__ $$aBIB 000779649 982__ $$aEbook 000779649 983__ $$aOnline 000779649 994__ $$a92$$bISE