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Preface; Contents; Part I: Functional Organization of the Prefrontal Cortex in Human and Nonhuman Primates; Chapter 1: Neural Correlates of Strategic Decision-Making in the Primate Prefrontal Cortex; 1.1 Introduction; 1.2 Prefrontal Cortex and Intertemporal Choice; 1.3 Prefrontal Cortex and Reinforcement Learning; 1.4 Prefrontal Cortex and Strategic Decision-Making; 1.5 Conclusions; References; Chapter 2: Functional Division Among Prefrontal Cortical Areas in an Analog of Wisconsin Card Sorting Test; 2.1 Contribution of the Principal Sulcus Area (PS)
2.2 Contribution of the Orbitofrontal Cortex (OFC)2.3 Contribution of the Anterior Cingulate Sulcus Area (ACS); 2.4 Functional Division Among the PS, OFC, and ACS Areas; 2.5 Contribution of the Frontopolar Cortex (FPC); 2.6 Functional Division Between Anterior and Posterior PFC Areas; 2.7 Conclusion; References; Chapter 3: Working Memory Functions of the Prefrontal Cortex; 3.1 Introduction; 3.2 ``Working Memory ́́as a Cognitive Construct; 3.2.1 Working Memory as RAM; 3.2.2 The Multiple Component Model and Its Relation to the Dorsolateral PFC; 3.3 Sustained Activity in the PFC (and Elsewhere)
3.4 Working Memory Functions of the dlPFC3.5 Conclusion; References; Part II: The Prefrontal Cortex as an Integrator of Executive and Emotional Function; Chapter 4: Prefrontal Cortex Integration of Emotion and Cognition; 4.1 Overview; 4.2 The Limbic System Is Broadly Associated with Emotions; 4.2.1 Subcortical Limbic Structures; 4.2.2 Expansion of the Limbic System to the Prefrontal Cortex; 4.2.3 The Principal Cortical Targets of Some Subcortical Limbic Structures; 4.3 Systematic Structural Variation of the Cortex and Connections
4.3.1 Specialization of Prefrontal Limbic Cortices: Their Principal Cortical Connections4.3.2 Specialization of Prefrontal Eulaminate Areas; 4.3.3 Regularity in the Laminar Pattern of Connections Between Limbic and Eulaminate Cortices; 4.3.4 Thalamic Connections Differ According to the Systematic Variation of Prefrontal Areas; Specialization of Direct and Indirect Pathways Through the Thalamus to Prefrontal Areas; 4.4 Linkage of Areas Associated with Emotions and Cognition; 4.4.1 Disruption of Linkage Between Areas Associated with Emotions and Cognition in Neurologic and Psychiatric Diseases
Consequences for Disconnection of Cognition from Emotion in Society4.5 Summary and Conclusion; References; Chapter 5: Interaction of Dopamine and Glutamate Release in the Primate Prefrontal Cortex in Relation to Working Memory and Re...; 5.1 Introduction; 5.2 Important Roles of DA in the Prefrontal Cortex; 5.2.1 DA Changes in the Dorsolateral PFC (DLPFC); DA Changes Related to WM in the DLPFC; DA Changes Related to Reward Expectancy in the DLPFC; DA Changes Related to Unpredictable Reward in the DLPFC; 5.2.2 DA Changes in the Medial PFC; DA Changes Related to WM in the Medial PFC
2.2 Contribution of the Orbitofrontal Cortex (OFC)2.3 Contribution of the Anterior Cingulate Sulcus Area (ACS); 2.4 Functional Division Among the PS, OFC, and ACS Areas; 2.5 Contribution of the Frontopolar Cortex (FPC); 2.6 Functional Division Between Anterior and Posterior PFC Areas; 2.7 Conclusion; References; Chapter 3: Working Memory Functions of the Prefrontal Cortex; 3.1 Introduction; 3.2 ``Working Memory ́́as a Cognitive Construct; 3.2.1 Working Memory as RAM; 3.2.2 The Multiple Component Model and Its Relation to the Dorsolateral PFC; 3.3 Sustained Activity in the PFC (and Elsewhere)
3.4 Working Memory Functions of the dlPFC3.5 Conclusion; References; Part II: The Prefrontal Cortex as an Integrator of Executive and Emotional Function; Chapter 4: Prefrontal Cortex Integration of Emotion and Cognition; 4.1 Overview; 4.2 The Limbic System Is Broadly Associated with Emotions; 4.2.1 Subcortical Limbic Structures; 4.2.2 Expansion of the Limbic System to the Prefrontal Cortex; 4.2.3 The Principal Cortical Targets of Some Subcortical Limbic Structures; 4.3 Systematic Structural Variation of the Cortex and Connections
4.3.1 Specialization of Prefrontal Limbic Cortices: Their Principal Cortical Connections4.3.2 Specialization of Prefrontal Eulaminate Areas; 4.3.3 Regularity in the Laminar Pattern of Connections Between Limbic and Eulaminate Cortices; 4.3.4 Thalamic Connections Differ According to the Systematic Variation of Prefrontal Areas; Specialization of Direct and Indirect Pathways Through the Thalamus to Prefrontal Areas; 4.4 Linkage of Areas Associated with Emotions and Cognition; 4.4.1 Disruption of Linkage Between Areas Associated with Emotions and Cognition in Neurologic and Psychiatric Diseases
Consequences for Disconnection of Cognition from Emotion in Society4.5 Summary and Conclusion; References; Chapter 5: Interaction of Dopamine and Glutamate Release in the Primate Prefrontal Cortex in Relation to Working Memory and Re...; 5.1 Introduction; 5.2 Important Roles of DA in the Prefrontal Cortex; 5.2.1 DA Changes in the Dorsolateral PFC (DLPFC); DA Changes Related to WM in the DLPFC; DA Changes Related to Reward Expectancy in the DLPFC; DA Changes Related to Unpredictable Reward in the DLPFC; 5.2.2 DA Changes in the Medial PFC; DA Changes Related to WM in the Medial PFC