Nanoscale Insights into Ion-Beam Cancer Therapy / edited by Andrey V. Solov'yov.
Solov'yov, Andrey V. editor.
2017
RM847
Available Online

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Title Nanoscale Insights into Ion-Beam Cancer Therapy / edited by Andrey V. Solov'yov.
ISBN 9783319430300
3319430300
9783319430287
3319430289
DOI https://doi.org/10.1007/978-3-319-43030-0
Published Cham : Springer International Publishing : Imprint: Springer, 2017.
Language English
Description 1 online resource (xx, 498 pages) illustrations.
Item Number 10.1007/978-3-319-43030-0 doi
Call Number RM847
Dewey Decimal Classification 615.842
Summary This book provides a unique and comprehensive overview of state-of-the-art understanding of the molecular and nano-scale processes that play significant roles in ion-beam cancer therapy. It covers experimental design and methodology, and reviews the theoretical understanding of the processes involved. It offers the reader an opportunity to learn from a coherent approach about the physics, chemistry and biology relevant to ion-beam cancer therapy, a growing field of important medical application worldwide. The book describes phenomena occurring on different time and energy scales relevant to the radiation damage of biological targets and ion-beam cancer therapy from the molecular (nano) scale up to the macroscopic level. It illustrates how ion-beam therapy offers the possibility of excellent dose localization for treatment of malignant tumours, minimizing radiation damage in normal tissue whilst maximizing cell-killing within the tumour, offering a significant development in cancer therapy. The full potential of such therapy can only be realized by better understanding the physical, chemical and biological mechanisms, on a range of time and space scales that lead to cell death under ion irradiation. This book describes how, using a multiscale approach, experimental and theoretical expertise available can lead to greater insight at the nanoscopic and molecular level into radiation damage of biological targets induced by ion impact. The book is intended for advanced students and specialists in the areas of physics, chemistry, biology and medicine related to ion-beam therapy, radiation protection, biophysics, radiation nanophysics and chemistry, atomic and molecular physics, condensed matter physics, and the physics of interaction of charged particles with matter. One of the most important features of the book is the inclusive multiscale approach to the understanding of complex and highly interdisciplinary processes behind ion-beam cancer therapy, which stretches from the atomistic level up to the biological scale and is demonstrated to be in excellent agreement with experimental observations.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Digital File Characteristics text file PDF
Added Author Solov'yov, Andrey V. editor.
Available in Other Form Print version: 9783319430287
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Multiscale Physics of Ion-Beam Cancer Therapy
Theory of atomic and molecular collisions, quantum and classical molecular dynamics (theory)
Fundamental collisions (experiment, both electrons and ions, stress on biomolecules)
Dissociative electron attachment process
Ions propagation through biological medium
Irradiation of biological targets with ions
Monte Carlo track structure simulations
Radiation nanochemistry
Radiobiological effects
Advanced therapies based on nanoprocesses and technologies: radiobiological effects with nanoparticles
Treatment planning systems
Medical applications (overview of the heavy ion therapy medical centers and practices).

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