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000780232 019__ $$a978662857$$a978760682$$a979017548$$a979293741$$a979482708$$a979744848$$a984871369
000780232 020__ $$a9783319520674$$q(electronic book)
000780232 020__ $$a3319520679$$q(electronic book)
000780232 020__ $$z9783319520650
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000780232 0247_ $$a10.1007/978-3-319-52067-4$$2doi
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000780232 049__ $$aISEA
000780232 050_4 $$aRC387.5
000780232 08204 $$a617.4810443$$223
000780232 24500 $$aNeurobiological and psychological aspects of brain recovery /$$cLaura Petrosini, editor.
000780232 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2017]
000780232 264_4 $$c©2017
000780232 300__ $$a1 online resource.
000780232 336__ $$atext$$btxt$$2rdacontent
000780232 337__ $$acomputer$$bc$$2rdamedia
000780232 338__ $$aonline resource$$bcr$$2rdacarrier
000780232 347__ $$atext file$$bPDF$$2rda
000780232 4901_ $$aContemporary clinical neuroscience
000780232 504__ $$aIncludes bibliographical references and index.
000780232 5050_ $$aPreface; Contents; Contributors; 1 Structural Plasticity in Dendrites: Developmental Neurogenetics, Morphological Reconstructions, and Computational Modeling; Abstract; 1.1 Introduction; 1.2 Biomedical Relevance; 1.3 Developmental Neurogenetics; 1.3.1 Transcriptional Control of Dendritic Development and Cytoskeletal Modulation; 1.4 Neurogenetic and Neurogenomic Techniques; 1.5 Dendritic Reconstructions: Data Acquisition, File Formats, and Morphological Databases; 1.5.1 History and Progress in Tissue Labeling; 1.5.2 Advancements in Microscopy; 1.5.3 Advancements in Reconstruction Systems
000780232 5058_ $$a1.5.4 Large-Scale Databases1.5.5 File Formats and SWC; 1.6 Computational Modeling of Dendritic Growth; 1.7 Future Directions; Acknowledgements; References; 2 Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive; Abstract; 2.1 Introduction; 2.2 The Autophagy Machinery; 2.3 Basal Autophagy in Neurons; 2.4 The Role of Autophagy in Neurodevelopment and Neurogenesis; 2.5 Autophagy and Neurological Pathologies; 2.6 Autophagy in Neurodegenerative Diseases; 2.6.1 Alzheimer's Disease; 2.6.2 Parkinson's Disease; 2.6.3 Huntington's Disease; 2.7 Autophagy in CNS Trauma
000780232 5058_ $$a2.8 Traumatic Brain Injury2.9 Spinal Cord Injury; 2.10 Remote Degeneration After Focal CNS Damage; 2.11 Conclusions; Acknowledgements; 3 Environmental Enrichment Repairs Structural and Functional Plasticity in the Hippocampus; Abstract; 3.1 Effects of Experience in the Developing Brain; 3.2 Environmental Enrichment as Testable Scientific Concept; 3.3 Structural Changes; 3.3.1 Neurogenesis; 3.3.2 Postsynaptic Changes; 3.3.3 Presynaptic Changes; 3.3.4 Gliogenesis; 3.4 Functional Changes; 3.5 Hippocampus, EE and Disease; 3.5.1 Ischemia/Stroke; 3.5.2 Movement Disorders
000780232 5058_ $$a3.5.3 Inflammation and Stress3.5.4 Autism Spectrum Disorders; 3.6 Reopening of Critical Periods by EE: Therapeutic Implications; Acknowledgements; References; 4 Translatable Models of Brain and Cognitive Reserve; Abstract; 4.1 The Theory of Brain and Cognitive Reserve and Supporting Evidence in Humans; 4.2 Necessity and Design of Animal Models; 4.3 Experimental Paradigms to Study BCR; 4.3.1 Animal Models of Brain Ageing; 4.3.2 Environmental Enrichment (EE); 4.3.3 Voluntary Exercise; 4.3.4 Antioxidants; 4.4 Putative Neurobiological Mechanisms of BCR; 4.4.1 Overview
000780232 5058_ $$a4.4.2 Synaptic, Cellular and Physiological Mediators4.4.2.1 Synaptogenesis and Synaptic Plasticity; 4.4.2.2 Adult Hippocampal Neurogenesis; 4.4.2.3 Glial Contributions; 4.4.2.4 Vascular Alterations; 4.4.3 Molecular Regulators; 4.4.3.1 Gene Expression, Epigenetic and Chromatin Modifications; 4.4.3.2 Neurotrophins; 4.4.3.3 Neurotransmitter and Neuromodulator Dynamics; 4.5 Conclusion; 4.5.1 Enviromimetics; 4.5.2 Room for Improvement; 4.5.3 Summary; References; 5 Cognitive Reserve: A Life-Course Perspective; Abstract; 5.1 Introduction; 5.2 Early Adulthood: Educational Attainment
000780232 506__ $$aAccess limited to authorized users.
000780232 520__ $$aThe novelty of this book's approach lies in addressing the impact of neurobiological factors as well as psychological influences on brain recovery. There is growing evidence that emotional, motivational, and cognitive factors along with personality traits play a crucial role in brain plasticity, resilience, and recovery. Topics include synaptic and neuronal plasticity, development of brain reserves, biological markers, environmental factors, psychological profile, emotional resilience, and personality traits. By combining the latest research on neural mechanisms and on psychological resilience the authors hope that this book can lead to the development of better treatment strategies for functional recovery from brain damage.
000780232 588__ $$aOnline resource, title from PDF title page (viewed March 17, 2017).
000780232 650_0 $$aBrain$$xWounds and injuries$$xPatients$$xRehabilitation.
000780232 650_0 $$aBrain damage$$xPsychological aspects.
000780232 650_0 $$aDevelopmental neurobiology.
000780232 7001_ $$aPetrosini, Laura,$$eeditor.
000780232 77608 $$iPrint version:$$z3319520652$$z9783319520650$$w(OCoLC)966204486
000780232 830_0 $$aContemporary clinical neuroscience.
000780232 852__ $$bebk
000780232 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-52067-4$$zOnline Access$$91397441.1
000780232 909CO $$ooai:library.usi.edu:780232$$pGLOBAL_SET
000780232 980__ $$aEBOOK
000780232 980__ $$aBIB
000780232 982__ $$aEbook
000780232 983__ $$aOnline
000780232 994__ $$a92$$bISE