Linked e-resources
Details
Table of Contents
Preface; Contents; List of Contributors; Historical Perspective ofßBone Morphogenetic Proteins; 1 Bone Formation: Auto-induction; 2 Matrix-Induced Bone Formation: AßBiological Cascade; 3 Discovery ofßBone Morphogenetic Proteins; 4 BMP Structure; 5 BMP Receptors; 6 BMP Preclinical Studies; 7 BMP-7 inßArticular Cartilage Repair; 8 BMPs Beyond Bone; 9 BMP Clinical Studies; 10 Conclusion; References; The Systems Biology ofßBone Morphogenetic Proteins; 1 BMPs During Development; 2 Structure andßFunction; 3 BMP: InßVitro andßInßVivo Model Systems forßEndochondral Bone Differentiation.
4 Role ofßBMPs inßCartilage Repair andßRegeneration5 Role ofßBMPs inßBone Repair andßRegeneration; 6 BMPs inßDentin Repair andßRegeneration; 7 BMP-7 inßAcute andßChronic Kidney Failure; 8 BMPs inßGlucose Homeostasis; 9 BMP-7 andßCalcium andßPhosphate Homeostasis; 10 BMPs inßIron Homeostasis; 11 BMPs' Role inßRare Genetic Disorders; 12 BMP inßOncology; 13 Conclusion; References; Embryonic Skeletogenesis andßCraniofacial Development; 1 Introduction; 2 Embryonic Skeletogenesis; 2.1 Developmental Stages ofßOssification; 2.2 BMP andßOsteogenesis; 2.3 Functional Studies inßAnimal Models.
2.3.1 BMP andßOsteoblasts2.3.2 BMP andßChondrocytes; 2.3.3 BMP andßMesenchymal Cells; 2.3.4 BMP andßOsteoclasts; 2.3.5 BMP andßOther Cell Types inßSkeletal System; 2.4 BMP andßBone-Related Diseases; 3 Craniofacial Development; 3.1 Head Induction; 3.2 Facial Development andßAbnormalities; 3.2.1 BMP andßCleft Lip; 3.2.2 BMP, Facial Cleft, andßMidline Structure; 3.2.3 BMP andßCleft Palate; 3.3 Calvarial Vault andßCranial Base; 3.3.1 BMP andßSkull Formation; 3.3.2 BMP andßSuture Formation; 3.3.3 BMP andßCranial Base; 3.4 Mandibular Development andßTemporomandibular Joint Formation.
3.4.1 BMP andßMandible3.4.2 BMP andßtheßTemporomandibular Joint; 4 Perspective andßConclusions; References; BMP andßBMP Regulation: Structure andßFunction; 1 General Mechanisms forßBMP Binding toßBMP Type IßandßType II Receptors; 2 General Mechanisms forßBMP Inhibition andßAntagonism; 3 Noggin-Mediated Antagonism; 4 Follistatin Family-Mediated Antagonism; 5 Chordin Family-Mediated Antagonism; 6 DAN Family-Mediated Antagonism; 7 Prodomain Interactions andßLatent Complex Formation; 8 Co-receptors, Signal Enhancers, andßOther Antagonists; 9 Summary ofßBMP Regulation ThroughßDifferent Mechanisms.
4 Role ofßBMPs inßCartilage Repair andßRegeneration5 Role ofßBMPs inßBone Repair andßRegeneration; 6 BMPs inßDentin Repair andßRegeneration; 7 BMP-7 inßAcute andßChronic Kidney Failure; 8 BMPs inßGlucose Homeostasis; 9 BMP-7 andßCalcium andßPhosphate Homeostasis; 10 BMPs inßIron Homeostasis; 11 BMPs' Role inßRare Genetic Disorders; 12 BMP inßOncology; 13 Conclusion; References; Embryonic Skeletogenesis andßCraniofacial Development; 1 Introduction; 2 Embryonic Skeletogenesis; 2.1 Developmental Stages ofßOssification; 2.2 BMP andßOsteogenesis; 2.3 Functional Studies inßAnimal Models.
2.3.1 BMP andßOsteoblasts2.3.2 BMP andßChondrocytes; 2.3.3 BMP andßMesenchymal Cells; 2.3.4 BMP andßOsteoclasts; 2.3.5 BMP andßOther Cell Types inßSkeletal System; 2.4 BMP andßBone-Related Diseases; 3 Craniofacial Development; 3.1 Head Induction; 3.2 Facial Development andßAbnormalities; 3.2.1 BMP andßCleft Lip; 3.2.2 BMP, Facial Cleft, andßMidline Structure; 3.2.3 BMP andßCleft Palate; 3.3 Calvarial Vault andßCranial Base; 3.3.1 BMP andßSkull Formation; 3.3.2 BMP andßSuture Formation; 3.3.3 BMP andßCranial Base; 3.4 Mandibular Development andßTemporomandibular Joint Formation.
3.4.1 BMP andßMandible3.4.2 BMP andßtheßTemporomandibular Joint; 4 Perspective andßConclusions; References; BMP andßBMP Regulation: Structure andßFunction; 1 General Mechanisms forßBMP Binding toßBMP Type IßandßType II Receptors; 2 General Mechanisms forßBMP Inhibition andßAntagonism; 3 Noggin-Mediated Antagonism; 4 Follistatin Family-Mediated Antagonism; 5 Chordin Family-Mediated Antagonism; 6 DAN Family-Mediated Antagonism; 7 Prodomain Interactions andßLatent Complex Formation; 8 Co-receptors, Signal Enhancers, andßOther Antagonists; 9 Summary ofßBMP Regulation ThroughßDifferent Mechanisms.