RUNX proteins in development and cancer / Yoram Groner, Yoshiaki Ito, Paul Liu, James C. Neil, Nancy A. Speck, Andre van Wijnen, editors.
Groner, Yoram, editor.; Ito, Yoshiaki, editor.; Liu, Pu Paul, editor.; Neil, James C, editor.; Speck, Nancy A, editor.; Van Wijnen, Andre J., editor.
2017
QP624.75.P74
Available Online

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Title RUNX proteins in development and cancer / Yoram Groner, Yoshiaki Ito, Paul Liu, James C. Neil, Nancy A. Speck, Andre van Wijnen, editors.
ISBN 9789811032332 (electronic book)
9811032335 (electronic book)
9789811032318 (hardcover)
9811032319 (hardcover)
DOI https://doi.org/10.1007/978-981-10-3233-2
Published Singapore : Springer, [2017]
Copyright ©2017
Language English
Description 1 online resource (xx, 515 pages) : illustrations.
Other Standard Identifiers 10.1007/978-981-10-3233-2 doi
Call Number QP624.75.P74
Dewey Decimal Classification 572.8/6
Summary "This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29 chapters, humans and other mammals have three RUNX genes that are known to play specific roles in blood, bone and neuronal development. However, their evolutionary history has recently been traced back to unicellular organisms and their involvement in many well-known signaling pathways (Wnt, TGFb, Notch, Hippo) is indicative of a more general function in cell biology. Their documented roles in cell fate decisions include control of proliferation, differentiation, survival, senescence and autophagy"--Publisher's description.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Digital File Characteristics text file PDF
Source of Description Online resource; title from pdf title page (SpringerLink, viewed March 20, 2017).
Description based on print version record.
Added Author Groner, Yoram, editor.
Ito, Yoshiaki, editor.
Liu, Pu Paul, editor.
Neil, James C, editor.
Speck, Nancy A, editor.
Van Wijnen, Andre J., editor.
Series Advances in experimental medicine and biology ; v. 962.
Available in Other Form RUNX proteins in development and cancer.
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
All Resources
Evolution of RUNX genes. RUNX in invertebrates / S. Hughes, A. Woollard
RUNX and CBF[beta] structure and biophysics of CBF[beta]/RUNX and its translocation products / Tahir H. Tahirov, John Bushweller
Covalent modifications of RUNX proteins: structure affects function / Ezra Blumenthal, Sarah Greenblatt, Guang Huang, Koji Ando, Ye Xu, Stephen D. Nimer
RUNX genes and mammalian development. The role of Runx1 in embryonic blood cell formation / Amanda D. Yzaguirre, Marella F.T.R. de Bruijn, Nancy A. Speck
Runx1 structure and function in blood cell development / Constanze Bonifer, Elena Levantini, Valerie Kouskoff, Georges Lacaud
Roles of Runx2 in skeletal development / Toshihisa Komori
Mitotic gene bookmarking: an epigenetic mechanism for coordination of lineage commitment, cell identity and cell growth / Sayyed K. Zaidi, Jane B. Lian, Andre van Wijnen, Janet L. Stein, Gary S. Stein
Roles of Runx genes in nervous system development / Jae Woong Wang, Stefano Stifani
Runx family genes in tissue stem cell dynamics / Chelsia Qiuxia Wang, Michelle Meng Huang Mok, Tomomasa Yokomizo, Vinay Tergaonkar [and others]
Roles of the RUNX1 enhancer in normal hematopoiesis and leukemogenesis / Wei-Siang Liau, Phuong Cao Thi Ngoc, Takaomi Sanda
RUNX1 and CBF[beta] fusion proteins in leukemia. RUNX1-ETO leukemia / Shan Lin, James C. Mulloy, Susumu Goyama
Clinical relevance of RUNX1 and CBFB alterations in acute myeloid leukemia and other hematological disorders / Klaus H. Metzeler, Clara D. Bloomfield
Mechanism of ETV6-RUNX1 leukemia / Aishwarya Sundaresh, Owen Williams
ETV6-RUNX1 + acute lymphoblastic leukaemia in identical twins / Anthony M. Ford Ph. D., Mel Greaves FRS
Molecular basis and targeted inhibition of CBF[beta]-SMMHC acute myeloid leukemia / Lucio H. Castilla, John H. Bushweller
RUNX and CBF[beta] in cancer and immune function. The RUNX genes as conditional oncogenes: insights from retroviral targeting and mouse models / James C. Neil, Kathryn Gilroy, Gillian Borland, Jodie Hay, Anne Terry, Anna Kilbey
RUNX1 and CBF[beta] mutations and activities of their wild-type alleles in AML / R. Katherine Hyde, Paul Liu, Alan D. Friedman
Roles of RUNX in B cell immortalisation / Michelle J. West, Paul J. Farrell
Roles of RUNX in Solid Tumors / Linda Shyue Huey Chuang, Kosei Ito, Yoshiaki Ito
RUNX3 and p53: how two tumor suppressors cooperate against oncogenic ras? / Jung-Won Lee, Andre van Wijnen, Suk-Chul Bae
RUNX and CBF[beta] in cancer and immune function. Runx3 and cell fate decisions in pancreas cancer / Martin C. Whittle, Sunil R. Hingorani
Runx genes in breast cancer and the mammary lineage / Nicholas Rooney, Alessandra I. Riggio, Daniel Mendoza-Villanueva, Paul Shore [and others]
Runx3 in immunity, inflammation and cancer / Joseph Lotem, Ditsa Levanon, Varda Negreanu, Omri Bauer, Shay Hantisteanu [and others]
Roles of RUNX complexes in immune cell development / Takashi Ebihara, Wooseok Seo, Ichiro Taniuchi
CBF[beta] and HIV infection / Dong Young Kim, John D. Gross
Emerging roles for RUNX. Roles of RUNX in hippo pathway signaling / Antonino Passaniti, Jessica L. Brusgard, Yiting Qiao, Marius Sudol [and others]
Roles of RUNX in hypoxia-induced responses and angiogenesis / Sun Hee Lee, Sarala Manandhar, You Mie Lee
The emerging roles of RUNX transcription factors in epithelial-mesenchymal transition / Dominic Chih-Cheng Voon, Jean Paul Thiery
A regulatory role for RUNX1, RUNX3 in the maintenance of genomic integrity / Vaidehi Krishnan, Yoshiaki Ito.

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