000780471 000__ 04718cam\a2200529Ii\4500 000780471 001__ 780471 000780471 005__ 20230306143012.0 000780471 006__ m\\\\\o\\d\\\\\\\\ 000780471 007__ cr\nn\nnnunnun 000780471 008__ 170330s2017\\\\sz\a\\\\o\\\\\000\0\eng\d 000780471 019__ $$a980226198$$a980414807$$a980718218$$a981021306$$a981133688 000780471 020__ $$a9783319525426$$q(electronic book) 000780471 020__ $$a3319525425$$q(electronic book) 000780471 020__ $$z9783319525419 000780471 020__ $$z3319525417 000780471 035__ $$aSP(OCoLC)ocn980006216 000780471 035__ $$aSP(OCoLC)980006216$$z(OCoLC)980226198$$z(OCoLC)980414807$$z(OCoLC)980718218$$z(OCoLC)981021306$$z(OCoLC)981133688 000780471 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dGW5XE$$dN$T$$dEBLCP$$dYDX$$dUAB$$dNJR$$dUPM$$dOCLCF$$dIOG$$dCOO 000780471 049__ $$aISEA 000780471 050_4 $$aRC600 000780471 08204 $$a616.97/8$$223 000780471 24500 $$aIgG4-related disease /$$cKazuichi Okazaki, editor. 000780471 2463_ $$aImmunoglobulin G4-related disease 000780471 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2017] 000780471 300__ $$a1 online resource (vii, 128 pages) :$$billustrations 000780471 336__ $$atext$$btxt$$2rdacontent 000780471 337__ $$acomputer$$bc$$2rdamedia 000780471 338__ $$aonline resource$$bcr$$2rdacarrier 000780471 4901_ $$aCurrent topics in microbiology and immunology ;$$vvolume 401 000780471 5050_ $$aPreface; Contents; 47 Current Concept of IgG4-Related Disease; Abstract; 1 The History of IgG4-Related Disease: Before and After Discovery of IgG4 (TableĀ 1); 2 Current Concepts of IgG4-RD; 3 Nomenclatures and Individual Organ Manifestation of IgG4-RD; 3.1 Type 1 Autoimmune Pancreatitis (IgG4-Related Pancreatitis); 3.2 IgG4-Related Sclerosing Cholangitis (IgG4-SC); 3.3 IgG4-Related Dacryoadenitis and Sialoadenitis (Formerly Called Mikulicz's Disease); 3.4 IgG4-Related Ophthalmic Diseases (IgG4-Related OD); 3.5 IgG4-Related Kidney Disease (IgG4-Related KD) 000780471 5058_ $$a3.6 IgG4-Related Retroperitoneal Fibrosis (IgG4-Related RPF)3.7 IgG4-Related Pulmonary Diseases (IgG4-Related PD); 3.8 IgG4-Related Thyroid Disease; 3.9 IgG4-Related Aortitis/Periaortitis; 3.10 IgG4-Related Lymphadenopathy; Acknowledgment; References; 36 Diagnosis and Treatment of IgG4-Related Disease; Abstract; 1 Introduction; 2 Diagnosis; 2.1 Epidemiology; 2.2 Clinical Symptoms; 2.3 Laboratory Tests; 2.4 Imaging; 2.5 Histopathology; 2.6 Steroid Responsiveness; 2.7 Diagnostic Criteria; 3 Treatment; 3.1 Indication of Treatment; 3.2 Induction of Remission; 3.3 Relapse and Maintenance Therapy 000780471 5058_ $$a3.4 Treatment-Related Side Effects4 Prognosis; 5 Future Perspectives; References; 37 Immunogenetics of IgG4-Related AIP; Abstract; 1 Introduction; 2 Association Studies Using Polymorphic Markers in Candidate Genes; 2.1 Human Leukocyte Antigen (HLA) Complex; 2.2 Fc Receptor-Like 3 (FCRL3) Gene; 2.3 Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4; CD152) Gene; 2.4 Toll-Like Receptor 4 (TLR4) and Protein Tyrosine Phosphatase N22 (PTPN22) Genes; 3 Association Studies Using Genome-Wide Polymorphic Markers; 3.1 Microsatellite Markers 000780471 5058_ $$a3.2 Small-Scale GWAS for Detecting Genetic Factors Causing the Development of Lachrymal/Salivary Gland Lesions in AIP4 Conclusions and Future Perspectives; References; 38 The Histopathology of IgG4-Related Disease; Abstract; 1 Diagnosis of IgG4-Related Disease; 2 General Pathological Features of IgG4-RD; 2.1 Morphological Features; 2.2 Immunohistochemical Features; 3 Proposed Diagnostic Terminology for IgG4-RD; 4 Pancreatobiliary Manifestations; 5 Sialadenitis and Dacryoadenitis; 6 Lung Disease; 7 Periaortitis, Inflammatory Aneurysm, and Retroperitoneal Fibrosis; 8 Lymphadenopathy; 9 Summary 000780471 506__ $$aAccess limited to authorized users. 000780471 520__ $$aThis volume focuses on IgG4-related disease (IgG4-RD), a novel clinical entity involving multiple organs and of unknown origin, associated with the abundant infiltration of IgG4-positive cells. It consists of nine chapters written by prominent experts in the field and discusses the disease concept, diagnosis and treatment, as well as recent findings on its pathogenesis and pathophysiology. As such, it offers an invaluable source of information for researchers and clinicians alike. 000780471 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed March 30, 2017). 000780471 650_0 $$aAutoimmune diseases. 000780471 650_0 $$aImmunoglobulin G. 000780471 650_0 $$aKidneys$$xDiseases. 000780471 650_0 $$aPancreatitis. 000780471 7001_ $$aOkazaki, Kazuichi,$$d1953-$$eeditor. 000780471 77608 $$iPrint version:$$z3319525417$$z9783319525419$$w(OCoLC)966557884 000780471 830_0 $$aCurrent topics in microbiology and immunology ;$$v401. 000780471 852__ $$bebk 000780471 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-52542-6$$zOnline Access$$91397441.1 000780471 909CO $$ooai:library.usi.edu:780471$$pGLOBAL_SET 000780471 980__ $$aEBOOK 000780471 980__ $$aBIB 000780471 982__ $$aEbook 000780471 983__ $$aOnline 000780471 994__ $$a92$$bISE