Linked e-resources
Details
Table of Contents
Preface; Abstract; Contents; Heat Shock Proteins and Maternal Contribution to Oogenesis and Early Embryogenesis; 1 Introduction; 2 Invertebrates; 2.1 Drosophila melanogaster; 2.2 Caenorhabditis elegans; 3 Vertebrates; 3.1 Danio rerio; 3.2 Xenopus laevis/Xenopus tropicalis; 3.3 Mammals (Mus musculus); 4 Conclusion and Future Perspectives; References; The Unmysterious Roles of HSP90: Ovarian Pathology and Autoantibodies; 1 Introduction; 2 Autoimmunity and Ovarian Autoimmunity; 3 Antigens Involved in Ovarian Autoimmunity; 4 Heat Shock Proteins (HSPs)
5 Heat Shock Protein-90 (HSP90) in Ovarian Biology, Localization, and Function6 HSP90 Autoantibodies and Ovarian Pathology; 7 HSP90 Interactome; 8 Proposed Autoimmune-Mediated Ovarian Infertility via HSP90 as a Game Player; 9 Summary, Outlook, and Future Directions; References; The Role of Heat Shock Factors in Mammalian Spermatogenesis; 1 Spermatogenesis Overview; 2 General Characteristics of Heat Shock Transcription Factors; 3 The Role of HSFs in Spermatogenesis; 3.1 Patterns of HSF Expression in Mammalian Testes; 3.2 Relevance of HSFs for Normal Spermatogenesis
3.3 Interplay between HSF1 and HSF2 in Spermatogenesis3.4 Contribution of HSF1 and HSF2 to the Heat Shock Response in Testes; 3.5 HSF1 as a Quality Control Factor in Male Germ Cells; 4 Summary and Future Directions; References; Heat Shock Protein A2 (HSPA2): Regulatory Roles in Germ Cell Development and Sperm Function; 1 Introduction; 2 Structural and Biochemical Characteristics of the Hsp70 Family; 2.1 Overview of the Heat Shock Protein 70 Family; 2.2 Structural Features of the Heat Shock Protein 70 Family; 2.3 Structural Features of HSPA2; 2.4 The Importance of HSPA2 Complexation
2.5 HSP40 Co-Chaperone Regulation of HSP70 Function2.6 BAG6 Co-Chaperone Regulation of HSP70 Function; 3 The Role of Hspa2 in Male Germ Cell Development and Function; 3.1 The Role of HSPA2 in Mouse Germ Cell Development; 3.2 The Role of HSPA2 in Germ Cell Development of Non-rodent Species; 3.3 The Role of HSPA2 in Human Sperm Function; 4 Mechanisms Underpinning the Loss of Hspa2 from the Spermatozoa of Infertile Patients; 5 Conclusions; References; The Potential Functions of Small Heat Shock Proteins in the Uterine Musculature during Pregnancy; 1 The Myometrium during Pregnancy
1.1 Adaptation and Differentiation1.2 Contributions of Immune System Activation; 2 The HSPB Family; 3 Uterine Expression of HSPB Members; 3.1 HSPB1; 3.2 CRYAB (HSPB5); 3.3 HSPB8 and BAG3; 3.4 HSPB6; 4 Future Directions; References; The Role of Hsp70 in the Regulation of Autophagy in Gametogenesis, Pregnancy, and Parturition; 1 Introduction; 2 Gametogenesis; 3 Embryogenesis; 4 In Vitro Fertilization; 5 Pregnancy Complications; 6 Summary and Future Directions; References; Roles of Grp78 in Female Mammalian Reproduction; 1 Introduction
5 Heat Shock Protein-90 (HSP90) in Ovarian Biology, Localization, and Function6 HSP90 Autoantibodies and Ovarian Pathology; 7 HSP90 Interactome; 8 Proposed Autoimmune-Mediated Ovarian Infertility via HSP90 as a Game Player; 9 Summary, Outlook, and Future Directions; References; The Role of Heat Shock Factors in Mammalian Spermatogenesis; 1 Spermatogenesis Overview; 2 General Characteristics of Heat Shock Transcription Factors; 3 The Role of HSFs in Spermatogenesis; 3.1 Patterns of HSF Expression in Mammalian Testes; 3.2 Relevance of HSFs for Normal Spermatogenesis
3.3 Interplay between HSF1 and HSF2 in Spermatogenesis3.4 Contribution of HSF1 and HSF2 to the Heat Shock Response in Testes; 3.5 HSF1 as a Quality Control Factor in Male Germ Cells; 4 Summary and Future Directions; References; Heat Shock Protein A2 (HSPA2): Regulatory Roles in Germ Cell Development and Sperm Function; 1 Introduction; 2 Structural and Biochemical Characteristics of the Hsp70 Family; 2.1 Overview of the Heat Shock Protein 70 Family; 2.2 Structural Features of the Heat Shock Protein 70 Family; 2.3 Structural Features of HSPA2; 2.4 The Importance of HSPA2 Complexation
2.5 HSP40 Co-Chaperone Regulation of HSP70 Function2.6 BAG6 Co-Chaperone Regulation of HSP70 Function; 3 The Role of Hspa2 in Male Germ Cell Development and Function; 3.1 The Role of HSPA2 in Mouse Germ Cell Development; 3.2 The Role of HSPA2 in Germ Cell Development of Non-rodent Species; 3.3 The Role of HSPA2 in Human Sperm Function; 4 Mechanisms Underpinning the Loss of Hspa2 from the Spermatozoa of Infertile Patients; 5 Conclusions; References; The Potential Functions of Small Heat Shock Proteins in the Uterine Musculature during Pregnancy; 1 The Myometrium during Pregnancy
1.1 Adaptation and Differentiation1.2 Contributions of Immune System Activation; 2 The HSPB Family; 3 Uterine Expression of HSPB Members; 3.1 HSPB1; 3.2 CRYAB (HSPB5); 3.3 HSPB8 and BAG3; 3.4 HSPB6; 4 Future Directions; References; The Role of Hsp70 in the Regulation of Autophagy in Gametogenesis, Pregnancy, and Parturition; 1 Introduction; 2 Gametogenesis; 3 Embryogenesis; 4 In Vitro Fertilization; 5 Pregnancy Complications; 6 Summary and Future Directions; References; Roles of Grp78 in Female Mammalian Reproduction; 1 Introduction