000782146 000__ 04646cam\a2200517Ii\4500 000782146 001__ 782146 000782146 005__ 20230306143239.0 000782146 006__ m\\\\\o\\d\\\\\\\\ 000782146 007__ cr\cn\nnnunnun 000782146 008__ 170516s2017\\\\si\a\\\\o\\\\\001\0\eng\d 000782146 019__ $$a987351891 000782146 020__ $$a9789811037108$$q(electronic book) 000782146 020__ $$a9811037108$$q(electronic book) 000782146 020__ $$z9789811037092 000782146 020__ $$z9811037094 000782146 035__ $$aSP(OCoLC)ocn987302302 000782146 035__ $$aSP(OCoLC)987302302$$z(OCoLC)987351891 000782146 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dGW5XE$$dEBLCP$$dYDX$$dN$T$$dOCLCF$$dUAB 000782146 049__ $$aISEA 000782146 050_4 $$aQP551 000782146 08204 $$a572/.6$$223 000782146 24500 $$aProtein reviews.$$nVolume 17 /$$cM. Zouhair Atassi, editor. 000782146 264_1 $$aSingapore :$$bSpringer,$$c2017. 000782146 300__ $$a1 online resource (vii, 163 pages) :$$billustrations. 000782146 336__ $$atext$$btxt$$2rdacontent 000782146 337__ $$acomputer$$bc$$2rdamedia 000782146 338__ $$aonline resource$$bcr$$2rdacarrier 000782146 4901_ $$aAdvances in experimental medicine and biology,$$x0065-2598 ;$$vvolume 925 000782146 4901_ $$aProtein reviews ;$$vvolume 17 000782146 500__ $$aIncludes index. 000782146 5050_ $$aPreface; Contents; Aggregation of FET Proteins as a Pathological Change in Amyotrophic Lateral Sclerosis; 1 Introduction; 2 Structure and Physiological Functions of FET Proteins; 3 Pathological Inclusions Containing FET Proteins in ALS Cases; 4 In vitro Aggregation of Recombinant FET Proteins; 5 Concluding Remarks; References; Structural Changes Fundamental to Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Pore; 1 Introduction: Cystic Fibrosis and CFTR; 2 Understanding the Transport Mechanism in CFTR -- A Channel Derived from a Pump 000782146 5058_ $$a3 The Structure and Function of the CFTR Anion Channel4 CFTR Channel Gating; 5 Inferring the Structural Rearrangements During Gating; 5.1 Global Structure of the Pore; 5.2 Location of the Channel Gate(s); 5.3 What Kinds of Movements Do the MSDs Undergo During Gating?; 5.4 Effect of Mutations on Channel Gating; 6 How Can the Conformation of the Channel Pore Be Manipulated to Control CFTR Activity?; 7 Conclusions and Future Perspectives; References; Dual Roles for Epithelial Splicing Regulatory Proteins 1 (ESRP1) and 2 (ESRP2) in Cancer Progression 000782146 5058_ $$a1 ESRP1 and ESRP2: Splicing Regulatory Proteins Specifically Expressed in Epithelial Cells2 ESRP Expression Is Upregulated in Cancer Cells; 3 ESRPs Negatively Regulate Cell Motility Through Multiple Mechanisms; 4 Dual Roles of ESRPs on Cancer Progression; 5 Possible Functional Differences Between ESRP1 and ESRP2; 6 Concluding Remarks; References; Controlling Autolysis During Flagella Insertion in Gram-Negative Bacteria; 1 Introduction; 2 Bacterial Flagellum Biosynthesis; 3 Peptidoglycan Degrading Enzymes; 3.1 Role in Flagella Assembly; 3.2 beta-N-Acetylglucosaminidases; 3.2.1 Families 000782146 5058_ $$a3.2.2 Mechanism of Action3.3 Lytic Transglycosylases; 3.3.1 Families; 3.3.2 Mechanism of Action; 4 Modulation of Flagella-Specific Autolysins; 4.1 Control of Autolysins at the Enzyme Level; 4.2 Control and Modulation of Flagella-Specific Autolytic Activity; 5 Concluding Remarks; References; Regulation of Skeletal Muscle Myoblast Differentiation and Proliferation by Pannexins; 1 Pannexins; 2 Pannexin Expression in Skeletal Muscle; 3 Post-translational Modifications of Panx1 and Panx3; 3.1 Glycosylation; 3.2 Phosphorylation; 3.3 Caspase Cleavage; 3.4 S-Nitrosylation 000782146 5058_ $$a4 Skeletal Muscle Myogenesis and Regeneration4.1 Panx1 Channels Mediate the Acquisition of Myogenic Commitment; 4.2 Panx1 Channels Promote Skeletal Muscle Myoblast Differentiation and Fusion; 4.3 Panx3 Channels Regulate the Proliferation, Differentiation, and Fusion of Skeletal Muscle Myoblasts; 5 Pannexins in Skeletal Muscle Health and Disease; 6 Concluding Remarks; References; Hyaluronidase and Chondroitinase; 1 Glycosaminoglycans; 2 CS/DS and HA-Degrading Enzymes; 2.1 Hyaluronidases (HAases); 2.1.1 Endo-beta-N-Acetylhexosaminidase; 2.1.2 Endo-beta-D-Glucuronidase; 2.1.3 HA Lyase 000782146 506__ $$aAccess limited to authorized users. 000782146 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 22, 2017). 000782146 650_0 $$aProteins. 000782146 7001_ $$aAtassi, M. Zouhair$$eeditor. 000782146 77608 $$iPrint version:$$z9811037094$$z9789811037092$$w(OCoLC)967369971 000782146 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 925. 000782146 830_0 $$aProtein reviews ;$$vv. 17. 000782146 852__ $$bebk 000782146 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-10-3710-8$$zOnline Access$$91397441.1 000782146 909CO $$ooai:library.usi.edu:782146$$pGLOBAL_SET 000782146 980__ $$aEBOOK 000782146 980__ $$aBIB 000782146 982__ $$aEbook 000782146 983__ $$aOnline 000782146 994__ $$a92$$bISE