000782166 000__ 04533cam\a2200469Ii\4500 000782166 001__ 782166 000782166 005__ 20230306143240.0 000782166 006__ m\\\\\o\\d\\\\\\\\ 000782166 007__ cr\cn\nnnunnun 000782166 008__ 170518s2017\\\\sz\a\\\\o\\\\\001\0\eng\d 000782166 020__ $$a9783319522746$$q(electronic book) 000782166 020__ $$a3319522744$$q(electronic book) 000782166 020__ $$z9783319522739 000782166 035__ $$aSP(OCoLC)ocn987438788 000782166 035__ $$aSP(OCoLC)987438788 000782166 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dEBLCP$$dGW5XE$$dN$T$$dYDX$$dOCLCF$$dUAB 000782166 049__ $$aISEA 000782166 050_4 $$aRD755.5 000782166 08204 $$a617.9/56$$223 000782166 24502 $$aA modern approach to biofilm-related orthopaedic implant infections :$$bAdvances in microbiology, infectious diseases and public health.$$nVolume 5 /$$cLorenzo Drago, editor. 000782166 264_1 $$aCham, Switzerland :$$bSpringer,$$c2017. 000782166 300__ $$a1 online resource (vi, 119 pages) :$$bcolor illustrations. 000782166 336__ $$atext$$btxt$$2rdacontent 000782166 337__ $$acomputer$$bc$$2rdamedia 000782166 338__ $$aonline resource$$bcr$$2rdacarrier 000782166 4901_ $$aAdvances in experimental medicine and biology,$$x0065-2598 ;$$vvolume 971 000782166 500__ $$aIncludes index. 000782166 5050_ $$aThe Concept of Biofilm-Related Implant Malfunction and 'Low-Grade Infection; 1 Introduction; 2 Biofouling in Industry and Working Machines; 3 Biofilms and Biofouling in Implanted Biomaterials; 4 Biofilm-Related Malfunction, Low- and High-Grade Infection and Thresholds for Clinical Interference; 4.1 Subclinical Contamination and Implant Malfunction; 4.2 Low-Grade Infection; 4.3 High-Grade Infection; 5 Conclusions; References; Mechanisms of Bacterial Colonization of Implants and Host Response; 1 Introduction; 2 Bacteria and Host: A Complex and Multifaceted Relationship 000782166 5058_ $$a3 Colonization of Implants: The First Step of Implant Infection4 Inflammation: An Essential and Telling Response to Infection; 5 The Host Response to Bacterial Infection; 6 Host Defense Against Bacterial Biofilms; 7 When and Why Biofilms Cause Implant-Associated Infections?; References; Animal Models of Implant-Related Low-Grade Infections. A Twenty-Year Review; 1 Introduction; 2 Methods: Inclusion Criteria and Search Strategy; 3 Results and Discussion; 3.1 Animal Species, Bacterial Strain, Site of Inoculum and Type of Implants 000782166 5058_ $$a3.2 Animal Models of Orthopedic Infections Induced by Highly Virulent Pathogens at Low Bacterial Inocula3.2.1 Models of Post-traumatic Osteomyelitis by Direct Injection of Bacterial Suspensions; 3.2.2 Models of Osteomyelitis by Bacterial-Loaded Carriers; 3.2.3 Models of Implant-Related Orthopedic Infections: Intramedullary Devices; 3.2.4 Models of Intramedullary Antimicrobial Treatment of Implant-Related Infections; 3.2.5 Models of Implant-Related Orthopedic Infections: Unicortical Bone Defects; 3.2.6 Models of Osteomyelitis in Synthesized Fractures 000782166 5058_ $$a3.3 Animal Models of Orthopedic Infections Induced by Low Virulent Pathogens4 Conclusions; References; Microbiological Diagnosis of Implant-Related Infections: Scientific Evidence and Cost/Benefit Analysis of Routine Antibiofilm Processing; 1 Introduction; 2 Microbial Etiology of PJIs; 2.1 Biofilm Related Infections; 2.2 Microorganisms Responsible of PJIs; 2.2.1 Staphylococci; 2.2.2 Enterococci; 2.2.3 Streptococci; 2.2.4 Gram Negative Bacilli; 2.2.5 Anaerobes; 2.2.6 Uncommon Microorganisms; 3 Microbiological Diagnosis; 3.1 Preoperative Cultures; 3.2 Intra-operative Cultures 000782166 5058_ $$a3.2.1 Periprosthetic Tissues3.2.2 Sampling by Swabs; 3.2.3 Prosthetic Implants; 3.2.4 Gram Staining; 3.2.5 Susceptibility Testing; 3.3 Molecular Analysis; 4 National Recommendations for Diagnosis of PJIs; 5 Cost/Benefit Analysis of Microbiological Diagnosis; 6 Conclusions; References; The Role of Biomarkers for the Diagnosis of Implant-Related Infections in Orthopaedics and Trauma; 1 Introduction; 2 Conventional Diagnostic Tools for PJI Diagnosis; 3 Biomarkers in Medicine; 4 Biomarkers of Periprosthetic Joint Infection; 4.1 Serum Biomarkers; 4.2 Synovial Biomarkers 000782166 506__ $$aAccess limited to authorized users. 000782166 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 24, 2017). 000782166 650_0 $$aImplants, Artificial$$xComplications. 000782166 650_0 $$aBiofilms. 000782166 7001_ $$aDrago, Lorenzo,$$eeditor. 000782166 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 971. 000782166 852__ $$bebk 000782166 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-52274-6$$zOnline Access$$91397441.1 000782166 909CO $$ooai:library.usi.edu:782166$$pGLOBAL_SET 000782166 980__ $$aEBOOK 000782166 980__ $$aBIB 000782166 982__ $$aEbook 000782166 983__ $$aOnline 000782166 994__ $$a92$$bISE