Part I: Mitochondrial Calcium Signaling. Mitochondrial Ca2+ Handling and Behind: The Importance of Being in Contact with Other Organelles / Riccardo Filadi, Pierre Theurey, Alice Rossi, Chiara Fedeli, and Paola Pizzo
Molecular Players of Mitochondrial Calcium Signaling: Similarities and Different Aspects in Various Organisms / Vanessa Checchetto, Diego De Stefani, Anna Raffaello, Rosario Rizzuto, and Ildiko Szabo
PART II. The mitochondrial permeability transition pore: structure and function. The Mitochondrial Permeability Transition Pore: Molecular Structure and Function in Health and Disease / Elizabeth A. Jonas, George A. Porter Jr., Gisela Beutner, Nelli Mnatsakanyan, Han-A. Park, Nikita Mehta, Rongmin Chen, and Kambiz N. Alavian
Mitochondrial calcium uptake in activation of the permeability transition core and cell death / Maria E. Solesio and Evgeny V. Pavlov
PART III. Mitochondrial outer membrane transport systems: structure, function, and physiological implications. Voltage-dependent anion channels and tubulin: bioenergetic controllers in cancer cells / Eduardo N. Maldonado, David N. DeHart, and John J. Lemasters
An assessment of how VDAC structures have impacted our understanding of their function / Lucie Bergodoll, Michael Grabe, and Jeff Abramson
Plant VDAC permeability: molecular bases and role in oxidative stress / Fabrice Homblé, Hana Kmita, Hayet Saidani, and Marc Léonetti
Lipids in regulation of the mitochondrial outer membrane permeability, bioenergetics, and metabolism / Tatiana K. Rostovtseva, David P. Hoogerheide, Amandine Rovini, and Sergey M. Bezrukov
The mitochondrial outer membrane potential as an electrical feedback control of cell energy metabolism / Victor V. Lemeshko
PART IV. Mitochondria and cellular signaling network. New insights on the regulation of programmed cell death by Bcl-2 family proteins at the mitochondria: physiological and pathophysiological implications / Laurent Dejean and Stéphen Manon
The 18 kDa translocator protein (TSPO): cholesterol trafficking and the biology of a prognostic and therapeutic mitochondrial target / Michele Frison, Anna Katherina Mallach, Emma Kennedy, and Michelangelo Campanella
Protein import channels in the crossroads of mitochondrial function / Ma Su Su Aung, Ruth Hartke, Stephen Madamba, Oygul Mirzalieva, and Pablo M. Peixoto
Substrate selection and its impact on mitochondrial respiration and redox / Sonia Cortassa, Steven J. Sollott, and Miguel A. Aon.