000789734 000__ 05321cam\a2200505Ii\4500 000789734 001__ 789734 000789734 005__ 20230306143337.0 000789734 006__ m\\\\\o\\d\\\\\\\\ 000789734 007__ cr\un\nnnunnun 000789734 008__ 170609t20172017sz\a\\\\ob\\\\000\0\eng\d 000789734 019__ $$a992346353$$a992740510 000789734 020__ $$a9783319483825$$q(electronic book) 000789734 020__ $$a331948382X$$q(electronic book) 000789734 020__ $$z9783319483801 000789734 020__ $$z3319483803 000789734 035__ $$aSP(OCoLC)ocn989732890 000789734 035__ $$aSP(OCoLC)989732890$$z(OCoLC)992346353$$z(OCoLC)992740510 000789734 040__ $$aMMU$$beng$$erda$$cMMU$$dOCLCO$$dGW5XE$$dN$T$$dEBLCP$$dYDX$$dOCLCF$$dCASUM$$dUAB$$dOCLCO 000789734 049__ $$aISEA 000789734 050_4 $$aRC628 000789734 08204 $$a616.3/98$$223 000789734 24500 $$aObesity and lipotoxicity /$$cAyse Basak Engin, Atilla Engin, editors. 000789734 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2017] 000789734 264_4 $$c©2017 000789734 300__ $$a1 online resource (viii, 624 pages) :$$billustrations. 000789734 336__ $$atext$$btxt$$2rdacontent 000789734 336__ $$astill image$$bsti$$2rdacontent 000789734 337__ $$acomputer$$bc$$2rdamedia 000789734 338__ $$aonline resource$$bcr$$2rdacarrier 000789734 4901_ $$aAdvances in experimental medicine and biology,$$x2214-8019 ;$$vvolume 960 000789734 504__ $$aIncludes bibliographical references and index. 000789734 5050_ $$aThe definition and prevalence of obesity and metabolic syndrome / Atilla Engin -- Circadian rhythms in diet-induced obesity / Atilla Engin -- Eat and death: chronic over-eating / Atilla Engin -- Obesity, persistent organic pollutants and related health problems / Loukia Vassilopoulou, Christos Psycharakis, Demetrios Petrakis, John Tsiaoussis [and others] -- Human protein kinases and obesity / Atilla Engin -- Fat cell and fatty acid turnover in obesity / Atilla Engin -- Adipose tissue function and expandability as determinants of lipotoxicity and the metabolic syndrome / Stefania Carobbio, Vanessa Pellegrinelli, Antonio Vidal-Puig -- What is lipotoxicity? / Ayse Basak Engin -- The pathogenesis of obesity-associated adipose tissue inflammation / Atilla Engin -- Microbiota and lipotoxicity / Evren Doruk Engin -- Endoplasmic reticulum stress and obesity / Erkan Yilmaz -- Insulin resistance, obesity and lipotoxicity / Dilek Yazıcı, Havva Sezer -- Adipose tissue hypoxia in obesity and its impact on preadipocytes and macrophages: hypoxia hypothesis / Atilla Engin -- Adipocyte-macrophage cross-talk in obesity / Ayse Basak Engin -- Endothelial dysfunction in obesity / Atilla Engin -- Diet-induced obesity and the mechanism of leptin resistance / Atilla Engin -- Influence of antioxidants on leptin metabolism and its role in the pathogenesis of obesity / Harald Mangge, Christian Ciardi, Kathrin Becker, Barbara Strasser, Dietmar Fuchs [and others] -- Adiponectin-resistance in obesity / Atilla Engin -- Non-alcoholic fatty liver disease / Atilla Engin -- Lipotoxicity-related hematological disorders in obesity / Ibrahim Celalettin Haznedaroglu, Umit Yavuz Malkan -- MicroRNA and adipogenesis / Ayse Basak Engin -- The interactions between kynurenine, folate, methionine and pteridine pathways in obesity / Ayse Basak Engin, Atilla Engin -- Eligibility and success criteria for bariatric/metabolic surgery / Manuel F. Landecho, Víctor Valentí, Rafael Moncada, Gema Frühbeck -- Does bariatric surgery improve obesity associated comorbid conditions / Atilla Engin -- Obesity-associated breast cancer: analysis of risk factors / Atilla Engin -- Lipotoxicity in obesity: benefit of olive oil / Saad Elias, Sbeit Wisam, Arraf Luai, Barhoum Massad, Assy. 000789734 506__ $$aAccess limited to authorized users. 000789734 520__ $$a"Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. "Obesity and Lipotoxicity" is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. "Lipotoxicity and Obesity" will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field"--Publisher's description. 000789734 588__ $$aDescription based on online resource; title from pdf title page (SpringerLink, viewed June 9, 2017). 000789734 650_0 $$aObesity. 000789734 650_0 $$aLipids$$xMetabolism$$xDisorders. 000789734 7001_ $$aEngin, Ayse Basak,$$eeditor. 000789734 7001_ $$aEngin, Atilla,$$eeditor. 000789734 77608 $$iPrint version:$$tObesity and lipotoxicity$$dCham, Switzerland : Springer, [2017]$$z9783319483801$$w(DLC) 2017934470$$w(OCoLC)959035236 000789734 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 960. 000789734 852__ $$bebk 000789734 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-48382-5$$zOnline Access$$91397441.1 000789734 909CO $$ooai:library.usi.edu:789734$$pGLOBAL_SET 000789734 980__ $$aEBOOK 000789734 980__ $$aBIB 000789734 982__ $$aEbook 000789734 983__ $$aOnline 000789734 994__ $$a92$$bISE