000796561 000__ 04659cam\a2200517Ii\4500 000796561 001__ 796561 000796561 005__ 20230306143452.0 000796561 006__ m\\\\\o\\d\\\\\\\\ 000796561 007__ cr\cnunnnunuuu 000796561 008__ 170801s2017\\\\sz\a\\\\o\\\\\001\0\eng\d 000796561 019__ $$a999532526 000796561 020__ $$a9783319597492$$q(electronic book) 000796561 020__ $$a3319597493$$q(electronic book) 000796561 020__ $$z9783319597485 000796561 020__ $$z3319597485 000796561 035__ $$aSP(OCoLC)ocn997431161 000796561 035__ $$aSP(OCoLC)997431161$$z(OCoLC)999532526 000796561 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dEBLCP$$dGW5XE$$dYDX$$dNJR$$dN$T$$dUAB 000796561 049__ $$aISEA 000796561 050_4 $$aQP379 000796561 08204 $$a612.8/27$$223 000796561 08204 $$a610 000796561 24500 $$aDevelopment of the cerebellum from molecular aspects to diseases /$$cHassan Marzban, editor. 000796561 264_1 $$aCham, Switzerland :$$bSpringer,$$c2017. 000796561 300__ $$a1 online resource :$$billustrations 000796561 336__ $$atext$$btxt$$2rdacontent 000796561 337__ $$acomputer$$bc$$2rdamedia 000796561 338__ $$aonline resource$$bcr$$2rdacarrier 000796561 4901_ $$aContemporary clinical neuroscience 000796561 500__ $$aIncludes index. 000796561 5050_ $$aPreface; Contents; The Development of the Cerebellum: From the Beginnings; The Origin of the Cerebellum; Histogenesis; Development of the Cerebellar Nuclei; Development of Longitudinal Purkinje Cell Zones; Development of Connections; Development of the Folial Pattern; References; The Embryology and Anatomy of the Cerebellum; Introduction; Embryology of the Cerebellum; Anatomy and Histology of the Human Cerebellum; Functional Divisions of the Cerebellum; Cerebellar Cortex; Cerebellar Nuclei (CN); Cerebellar Peduncles; Cerebellar Function; Blood Supply of the Cerebellum 000796561 5058_ $$aPCs as Project Managers of Cerebellar Cytoarchitecture and Connectivity Cerebellar Anlagen and Germinal Zones; Establishment of Neurogenic Microdomains for GABAergic Progenitors; The Regulation of PC Progenitor Specification and Commitment; Ebf2 and PC Subtype Specification; Embryonic PC Cluster Formation; From Clusters to Zones and Stripes; Conclusions; References; Cerebellar Developmental Disorders and Cerebellar Nuclei; What Are Cerebellar Nuclei?; Cellular Anatomy and Diversity; Outputs of the Cerebellar Nuclei; Inputs to Cerebellar Nuclei; Development of Cerebellar Nuclei 000796561 5058_ $$aOrigin of Glutamatergic Neurons Origin of GABAergic Projection Neurons; Other GABAergic Neurons; Nucleogenesis and Cell Migration; Evolution and the Diversification of Cerebellar Nuclei; Cerebellar Nuclei and Disease; Future Perspectives on Cerebellar Nucleus Development; References; Motor Circuit Abnormalities During Cerebellar Development; Introduction; Structure of the Cerebellum; Development of the Cerebellar Circuit; The Role of Cerebellar Development in Ataxia, a Classical Cerebellar Movement Disorder; SCA1 (Spinocerebellar Ataxia Type 1) 000796561 5058_ $$aSCA6 (Spinocerebellar Ataxia Type 6) Car8wdl (The waddles Spontaneous Mutant Mouse); L7Cre; Vgatflox/flox (Conditional Genetic Silencing of Purkinje Cell Neurotransmission); Cerebellar Development and Non-motor Disorders; References; Developmental Disorders of the Cerebellum and Neurotrophic Factors; Introduction; Neurotrophic Factors; Neurotrophins; Transforming Growth Factor-Beta Superfamily; Neurotrophic Cytokines; Neurotrophic Factors and Cerebellar Development; Cerebellum and Neurodevelopmental Disorders; Attention Deficit Hyperactivity Disorder; Autism Spectrum Disorders 000796561 506__ $$aAccess limited to authorized users. 000796561 520__ $$aThe authors present the most current and cutting-edge knowledge regarding the molecular basis of cerebellar development, focusing on information relevant to laboratory scientists and clinicians providing service to patients with cerebellar disorders. Knowledge obtained from advanced neuroimaging techniques that are used during development, and from molecular- and genetic-based studies has provided rapidly-growing evidence that the cerebellum is a brain region that is highly impacted by developmental defects. Cerebellar defects result in significant intellectual and motor function impairment that affects both the patients and their families. 000796561 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 7, 2017). 000796561 650_0 $$aCerebellum$$xGrowth. 000796561 650_0 $$aCerebellum$$xDiseases. 000796561 7001_ $$aMarzban, Hassan,$$eeditor. 000796561 77608 $$iPrint version:$$z9783319597485$$z3319597485$$w(OCoLC)985080724 000796561 830_0 $$aContemporary clinical neuroscience. 000796561 852__ $$bebk 000796561 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-59749-2$$zOnline Access$$91397441.1 000796561 909CO $$ooai:library.usi.edu:796561$$pGLOBAL_SET 000796561 980__ $$aEBOOK 000796561 980__ $$aBIB 000796561 982__ $$aEbook 000796561 983__ $$aOnline 000796561 994__ $$a92$$bISE