000798157 000__ 05371cam\a2200517Ii\4500
000798157 001__ 798157
000798157 005__ 20230306143509.0
000798157 006__ m\\\\\o\\d\\\\\\\\
000798157 007__ cr\un\nnnunnun
000798157 008__ 170819s2017\\\\si\a\\\\ob\\\\001\0\eng\d
000798157 019__ $$a1001548311
000798157 020__ $$a9789811045677$$q(electronic book)
000798157 020__ $$a9811045674$$q(electronic book)
000798157 020__ $$z9789811045660
000798157 020__ $$z9811045666
000798157 035__ $$aSP(OCoLC)on1001385706
000798157 035__ $$aSP(OCoLC)1001385706$$z(OCoLC)1001548311
000798157 040__ $$aEBLCP$$beng$$erda$$cEBLCP$$dOCLCO$$dN$T$$dMMU$$dOCLCO$$dYDX$$dN$T$$dGW5XE$$dUAB
000798157 049__ $$aISEA
000798157 050_4 $$aQH601
000798157 08204 $$a574.875$$223
000798157 24500 $$aOrganelle contact sites :$$bfrom molecular mechanism to disease /$$cMitsuo Tagaya, Thomas Simmen, editors.
000798157 264_1 $$aSingapore :$$bSpringer,$$c[2017]
000798157 264_4 $$c©2017
000798157 300__ $$a1 online resource (viii, 257 pages) :$$bcolor illustrations.
000798157 336__ $$astill image$$bsti$$2rdacontent
000798157 336__ $$atext$$btxt$$2rdacontent
000798157 337__ $$acomputer$$bc$$2rdamedia
000798157 338__ $$aonline resource$$bcr$$2rdacarrier
000798157 4901_ $$aAdvances in experimental medicine and biology,$$x2214-8019 ;$$vvolume 997
000798157 504__ $$aIncludes bibliographical references and index.
000798157 5050_ $$aOrganelle communication at membrane contact sites (MCS): from curiosity to center stage in cell biology and biomedical research / Thomas Simmen, Mitsuo Tagaya -- Over six decades of discovery and characterization of the architecture at mitochondria-associated membranes (MAMS) / Maria Sol Herrera-Cruz, Thomas Simmen -- Regulation of mitochondrial dynamics and autophagy by the mitochondria-associated membrane / Mitsuo Tagaya, Kohei Arasaki -- Endoplasmic reticulum-mitochondria communication through Ca2+ signaling: the importance of mitochondria-associated membranes (MAMS) / Saverio Marchi, Mart Bittremieux, Sonia Missiroli, Claudia Morganti, Simone Patergnani [and others] -- Ceramide transport from the endoplasmic reticulum to the trans Golgi region at organelle membrane contact sites / Kentaro Hanada -- Endoplasmic reticulum-plasma membrane crosstalk mediated by the extended synaptotagmins / Yasunori Saheki -- Endoplasmic reticulum-plasma membrane contacts regulate cellular excitability / Eamonn J. Dickson -- The lipid droplet and the endoplasmic reticulum / Yuki Ohsaki, Kamil Sołtysik, Toyoshi Fujimoto -- Role of intra- and inter-mitochondrial membrane contact sites in yeast phospholipid biogenesis / Yasushi Tamura, Toshiya Endo -- Discovery and roles of ER-endolysosomal contact sites in disease / William Mike Henne -- Alzheimer disease / Estela Area-Gomez, Eric A. Schon -- Mitochondrial-associated membranes in Parkinson's disease / Nobutaka Hattori, Taku Arano, Taku Hatano, Akio Mori, Yuzuru Imai -- Role of endoplasmic reticulum-mitochondria communication in type 2 diabetes / Jennifer Rieusset -- Mitochondrial-endoplasmic reticulum contact sites mediate innate immune responses / Takuma Misawa, Michihiro Takahama, Tatsuya Saitoh -- Hepatitis C virus replication / Tetsuro Suzuki -- Hijacking of membrane contact sites by intracellular bacterial pathogens / Isabelle Derré -- Alterations in Ca2+ signalling via ER-mitochondria contact site remodelling in cancer / Martijn Kerkhofs, Carlotta Giorgi, Saverio Marchi, Bruno Seitaj, Jan B. Parys [and others].
000798157 506__ $$aAccess limited to authorized users.
000798157 520__ $$a"This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders,  and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases.  Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come. This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction. Additionally, it will stimulate graduate students and postdocs who will energize, drive, and develop the research field in the near future"--Publisher's description.
000798157 588__ $$aOnline resource; title from PDF title page (viewed August 29, 2017)
000798157 650_0 $$aCell membranes$$xMetabolism.
000798157 650_0 $$aEndoplasmic reticulum$$xMetabolism.
000798157 650_0 $$aMitochondrial membranes$$xMetabolism.
000798157 650_0 $$aCell interaction.
000798157 7001_ $$aTagaya, Mitsuo,$$d1958-$$eeditor.
000798157 7001_ $$aSimmen, Thomas,$$eeditor.
000798157 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 997.
000798157 852__ $$bebk
000798157 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-10-4567-7$$zOnline Access$$91397441.1
000798157 909CO $$ooai:library.usi.edu:798157$$pGLOBAL_SET
000798157 980__ $$aEBOOK
000798157 980__ $$aBIB
000798157 982__ $$aEbook
000798157 983__ $$aOnline
000798157 994__ $$a92$$bISE