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000798293 019__ $$a1002457127
000798293 020__ $$a9783319585925$$q(electronic book)
000798293 020__ $$a3319585924$$q(electronic book)
000798293 020__ $$z9783319585918
000798293 020__ $$z3319585916
000798293 035__ $$aSP(OCoLC)on1002203870
000798293 035__ $$aSP(OCoLC)1002203870$$z(OCoLC)1002457127
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000798293 049__ $$aISEA
000798293 050_4 $$aQH600.2
000798293 08204 $$a572.8/7$$223
000798293 24500 $$aCentromeres and kinetochores :$$bdiscovering the molecular mechanisms underlying chromosome inheritance /$$cBen E. Black, editor.
000798293 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2017]
000798293 300__ $$a1 online resource :$$billustrations
000798293 336__ $$atext$$btxt$$2rdacontent
000798293 337__ $$acomputer$$bc$$2rdamedia
000798293 338__ $$aonline resource$$bcr$$2rdacarrier
000798293 4901_ $$aProgress in molecular and subcellular biology,$$x0079-6484 ;$$vv. 56
000798293 504__ $$aIncludes bibliographical references.
000798293 5050_ $$aPreface; Contents; Identification, Organization, and Regulation of Centromere and Kinetochore Components; 1 Use of Mass Spectrometry to Study the Centromere and Kinetochore; Abstract; 1 Discovery of Centromere Proteins Using Anti-centromere Autoantibodies; 2 Identification of Centromere Proteins Using Yeast Genetic Screens; 3 Post-genomics Approaches to Discover Centromere Proteins: RNAi Screening in C. elegans; 4 Identification of Centromere/Kinetochore Proteins by Affinity-Purification Mass Spectrometry (AP-MS); 5 Shotgun Proteomics of Isolated Yeast Kinetochores
000798293 5058_ $$a6 Shotgun Proteomics of Whole Isolated Mitotic Chromosomes7 Use of Mass Spectrometry to Study Kinetochore Protein Complexes; 8 Use of CLMS Mass Spectrometry to Study the Ultra-structure of Kinetochore Protein Complexes; 9 Future Prospects; Acknowledgements; References; 2 Critical Foundation of the Kinetochore: The Constitutive Centromere-Associated Network (CCAN); Abstract; 1 Introduction; 2 Centromere; 2.1 Centromere Organization; 2.2 CENP-A Is a Critical Epigenetic Mark for Centromere Specification; 3 CCAN Organization; 3.1 CCAN Subcomplexes; 3.1.1 CENP-C; 3.1.2 CENP-H/I/K/M; 3.1.3 CENP-L/N
000798293 5058_ $$a3.1.4 CENP-O/P/Q/R/U3.1.5 CENP-T/S/W/X; 3.2 CCAN Organization and Functions; 3.2.1 CCAN Interaction; 3.2.2 The CCAN as a Bridge Between Centromere and Microtubule; 3.2.3 In Vitro Reconstitution of the CCAN; 3.2.4 The CCAN-Dependent Stabilization of Centromere Position; 4 Dynamic Rearrangement of CCAN Organization; 4.1 Reorganization of the CCAN During the Cell Cycle; 4.2 CCAN Organization During Development; 5 Conclusion; Acknowledgements; References; 3 The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function; Abstract; 1 Introduction
000798293 5058_ $$a2 Reconstituting Centromere and Kinetochore Functions In Vitro2.1 Xenopus Egg Extract as a Versatile System for In Vitro Reconstitution; 3 Application of Frog Egg Extracts to Study Centromere and Kinetochore Function; 3.1 Epigenetic Maintenance of Centromere Identity; 3.2 CCAN Assembly; 3.3 Kinetochore Assembly; 3.4 The Spindle Assembly Checkpoint; 4 Conclusion; References; 4 Centrochromatin of Fungi; Abstract; 1 Introduction; 2 Centromeric DNA Sequence: Many Ways to Shape a Remarkable Genetic Locus; 2.1 The Dark Matter of Fungal Centromeres Lies in the Basal Lineages
000798293 5058_ $$a2.2 Fission Yeast, Budding Yeast, and the Dimorphic Candida as Models for Centromere Research2.3 Filamentous Fungi Contain Diverse Types of Centromeres; 3 Centrochromatin; 4 Summary; References; 5 Evolutionary Lessons from Species with Unique Kinetochores; Abstract; 1 Introduction; 2 The Kinetochore Complex in Animals and Fungi; 2.1 Similarities and Variations of the Inner Kinetochore in Animals and Fungi; 2.2 The Composition of the Outer Kinetochore Is Highly Conserved in Animals and Fungi; 3 Glimpses into Kinetochore Compositions in Diverse Eukaryotes; 3.1 Supergroup Amoebozoa
000798293 506__ $$aAccess limited to authorized users.
000798293 588__ $$aOnline resource; title from PDF title page (viewed Sept. 12, 2017).
000798293 588__ $$aDescription based on print version record.
000798293 650_0 $$aCentromere.
000798293 650_0 $$aChromosomes.
000798293 650_0 $$aProteins.
000798293 650_0 $$aCellular control mechanisms.
000798293 7001_ $$aBlack, Ben E.
000798293 77608 $$iPrint version:$$z9783319585918$$z3319585916$$w(OCoLC)982651812
000798293 830_0 $$aProgress in molecular and subcellular biology ;$$v56.
000798293 852__ $$bebk
000798293 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-58592-5$$zOnline Access$$91397441.1
000798293 909CO $$ooai:library.usi.edu:798293$$pGLOBAL_SET
000798293 980__ $$aEBOOK
000798293 980__ $$aBIB
000798293 982__ $$aEbook
000798293 983__ $$aOnline
000798293 994__ $$a92$$bISE