000798400 000__ 04664cam\a2200541Mi\4500 000798400 001__ 798400 000798400 005__ 20230306143523.0 000798400 006__ m\\\\\o\\d\\\\\\\\ 000798400 007__ cr\un\nnnunnun 000798400 008__ 170905s2017\\\\sz\a\\\\o\\\\\001\0\eng\d 000798400 019__ $$a1002848018$$a1002909155$$a1003098655 000798400 020__ $$a9783319580005$$q(electronic book) 000798400 020__ $$a3319580000$$q(electronic book) 000798400 020__ $$z9783319579986 000798400 0247_ $$a10.1007/978-3-319-58000-5$$2doi 000798400 035__ $$aSP(OCoLC)on1003467769 000798400 035__ $$aSP(OCoLC)1003467769$$z(OCoLC)1002848018$$z(OCoLC)1002909155$$z(OCoLC)1003098655 000798400 040__ $$aYDX$$beng$$cYDX$$dN$T$$dEBLCP$$dGW5XE$$dN$T$$dUAB 000798400 049__ $$aISEA 000798400 050_4 $$aRC685.A65 000798400 08204 $$a616.1/28$$223 000798400 08204 $$a610 000798400 24500 $$aCardiac arrhythmias, pacing and sudden death /$$cPeter Kowey, Jonathan P. Piccini, Gerald Naccarelli, James A. Reiffel, editors. 000798400 264_1 $$aCham :$$bSpringer International Publishing :$$bImprint: Springer,$$c2017. 000798400 300__ $$a1 online resource (xiii, 306 pages) :$$billustrations. 000798400 336__ $$atext$$btxt$$2rdacontent 000798400 337__ $$acomputer$$bc$$2rdamedia 000798400 338__ $$aonline resource$$bcr$$2rdacarrier 000798400 4901_ $$aCardiovascular medicine 000798400 500__ $$aIncludes index. 000798400 5050_ $$aForeword; Contents; Contributors; 1: Basic Electrophysiology; Introduction; The Cardiac Action Potential; What Is an Action Potential? (AP); How Is the Cardiac AP Generated?; Membrane Potential, Equilibrium Potential and Driving Force; Channel Gating; Stages of the Cardiac AP; Phase 4: the Resting Membrane Potential; Phase 0: The Rapid Upstroke; Phase 1: Early Repolarization; Phase 2: The AP Plateau; Phase 3: Repolarization; Contraction of Cardiac Myocytes; Ca2+-Induced Ca2+ Release; Excitation-Contraction Coupling; Automaticity: The Cardiac Pacemakers 000798400 5058_ $$aThe Membrane Clock Model The Ca2+ Clock Model; Other Currents; Cardiac Conduction; Cell-Cell Coupling; Arrhythmogenesis; Abnormal Automaticity; Afterdepolarizations and Triggered Activity; Early Afterdepolarizations (EADs); Delayed Afterdepolarizations (DADs); Reentry; Anatomical Reentry; Functional Reentry; References; 2: Pathophysiology of Atrial Fibrillation; Introduction; Conditions and Diseases That Affect AF Generation; Pathophysiology of AF Initiation: Triggers and Substrate; Pathophysiology of AF Maintenance: Atrial Electrical and Structural Remodeling 000798400 5058_ $$aAtrial Electrical Remodeling Atrial Structural Remodeling; Is There a "Vulnerable Window" for Development of AF in the Spectrum of Atrial Structural Remodeling?; Electrophysiological Mechanisms of AF: Focal and Reentry; References; 3: Genomics of Cardiac Arrhythmias; DNA Variants; Conventional Approaches to Finding Genes in Familial Traits; Contemporary Approaches to Finding Trait Associated Genetic Variation; The Genome-Wide Association Study; Specific Arrhythmias: Atrial Fibrillation; Specific Arrhythmias: Sudden Cardiac Death 000798400 5058_ $$aSpecific Arrhythmias: Drug-Induced Torsades de Pointes Antiarrhythmic Drug Pharmacogenetics; Summary and Cautionary Notes; References; 4: Channelopathies: Clinical Presentation and Genetics; Long QT Syndrome (LQTS); Clinical Presentation of LQTS; Genetic Basis and Genotype-Phenotype Correlations; Risk Stratification in LQTS; Brugada Syndrome (BrS); Clinical Presentation of BrS; Genetic Basis and Genotype-Phenotype Correlations; Risk Stratification in BrS; Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT); Clinical Presentation of CPVT 000798400 5058_ $$aGenetic Basis and Genotype-Phenotype Correlations of CPVT Risk Stratification in CPVT; References; 5: Extended ECG Monitoring; Introduction; Recording Systems for Extended Rhythm Monitoring; Holter-ECG; External Cardiac Event Recorders; Implantable Cardiac Monitors (ICMs); Clinical Applications of Non-invasive ECG Monitoring; Atrial Fibrillation and Cryptogenic Stroke; AF Burden Directing Medical or Invasive Management; Palpitations and Unknown Arrhythmia; Unexplained Syncope and Vasovagal Syncope; Screening for Ventricular Arrhythmia and Risk Assessment of Sudden Cardiac Death 000798400 506__ $$aAccess limited to authorized users. 000798400 650_0 $$aArrhythmia. 000798400 650_0 $$aHeart$$xElectric properties. 000798400 7001_ $$aKowey, Peter,$$eeditor. 000798400 7001_ $$aPiccini, Jonathan P.$$eeditor. 000798400 7001_ $$aNaccarelli, Gerald.$$eeditor. 000798400 7001_ $$aReiffel, James A.$$eeditor. 000798400 77608 $$iPrint version:$$z9783319579986 000798400 830_0 $$aCardiovascular medicine (Series) 000798400 85280 $$bebk$$hSpringerLink 000798400 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-58000-5$$zOnline Access$$91397441.1 000798400 909CO $$ooai:library.usi.edu:798400$$pGLOBAL_SET 000798400 980__ $$aEBOOK 000798400 980__ $$aBIB 000798400 982__ $$aEbook 000798400 983__ $$aOnline 000798400 994__ $$a92$$bISE