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From gene to therapy : understanding human disease through genetics / Michael Dean.

Dean, Michael Carlton, author.; ProQuest (Firm)
2017
RB155.5 .D424 2017
Available Online
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Title
From gene to therapy : understanding human disease through genetics / Michael Dean.
Author
Dean, Michael Carlton, author.
ISBN
9781615047536 (electronic book)
1615047530 (electronic book)
9781615047529
DOI
https://doi.org/10.4199/C00154ED1V01Y201707GBD008
Published
[San Rafael, California] : Morgan & Claypool, 2017.
Language
English
Description
1 online resource (ix, 91 pages) : illustrations.
Item Number
10.4199/C00154ED1V01Y201707GBD008 doi
Call Number
RB155.5 .D424 2017
Dewey Decimal Classification
616.042
Note
Part of: Colloquium digital library of life sciences.
Bibliography, etc. Note
Includes bibliographical references (pages 71-89).
Access Note
Access limited to authorized users
Reproduction
Electronic reproduction. Ann Arbor, MI Available via World Wide Web.
Source of Description
Title from PDF title page (viewed on October 3, 2017).
Added Corporate Author
ProQuest (Firm)
Series
Colloquium digital library of life sciences.
Colloquium series on the genetic basis of human disease ; # 8. 2168-4022
Available in Other Form
Print version: 9781615047529
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Online Access
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1. Cystic fibrosis: from family studies to gene mapping, cloning, and function to therapy


2. Cancer genetics and developmental biology
2.1 The PTCH gene and cancer stem cells


3. Chromosome alterations and cancer (MYC)
3.1 The Philadelphia chromosome
3.2 MYC and the cell cycle


4. Discovery of an AIDS resistance gene and development of a targeted therapy (CCR5)


5. Cancer in a petri dish: discovery of an oncogene (MET)
5.1 Oncogenes: background and historical context
5.2 The rearrangement that formed MET


6. Studying populations of cancer patients
6.1 Genome-wide association studies (GWAS)
6.2 MSMB gene


7. From cancer virus to cancer vaccine: HPV and cervical cancer


8. Sequencing the tumor genome


9. ABC genes: a gene family causing multiple diseases


10. An eye on macular degeneration and gene therapy


Conclusion
References
Author biography.

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