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Abbreviations; Contents; Contributor List; 1: Epilepsy, Status Epilepticus, and Refractory Status Epilepticus; 1.1 Epilepsy; 1.1.1 Definition of Epilepsy; 1.1.2 Classification of Epilepsy; 1.1.3 Refractory Epilepsy (RE); 1.2 Status Epilepticus; 1.2.1 Definition of SE; 1.2.2 Classification of SE; 1.3 Definition and Classification of RSE; 1.4 Diagnosis of Convulsive Epilepsy and Status Epilepticus; 1.4.1 Convulsive Epilepsy Versus Nonepileptic Convulsion; 1.4.2 Characteristics of Convulsive Epilepsy; 1.4.3 Characteristics of CSE; 1.4.4 Evaluation of Convulsive Epilepsy

1.4.5 Distinguish Nonepileptic Convulsion from Convulsive Epilepsy1.4.5.1 Convulsive Syncope; 1.4.5.2 Pheochromocytoma-Induced Convulsion; 1.4.5.3 Insulinoma-Induced Convulsion; 1.4.5.4 Hypertensive Encephalopathy- Induced Convulsion; 1.4.5.5 Convulsive Psychogenic Nonepileptic Seizures; 1.4.5.6 Hyperventilation Syndrome and Its Differentiation from Epilepsy; 1.4.5.7 Eclampsia; 1.5 Diagnosis of NCSE; 1.5.1 Definition of NCSE; 1.5.2 Incidence of NCSE; 1.5.3 Etiology of NCSE; 1.5.4 Clinical Manifestations of NCSE; 1.5.4.1 Generalized Typical Absence in NCSE Without Coma

1.5.4.2 Generalized Atypical Absence in NCSE Without Coma1.5.4.3 Myoclonic Absence in NCSE Without Coma; 1.5.4.4 Focal NCSE Without Impairment of Consciousness; 1.5.4.5 Focal NCSE with Aphasic Status; 1.5.4.6 Focal NCSE with Impairment of Consciousness; 1.5.4.7 NCSE Failure of Classification as Generalized or Focal Status; 1.5.5 Diagnosis of NCSE; 1.5.6 Treatment of NCSE; 1.6 Diagnosis of RSE; 1.6.1 Epidemiological Investigation of RSE; 1.6.2 Relative Factors of RSE; 1.6.2.1 Age; 1.6.2.2 Type of Onset of Status Epilepticus; 1.6.2.3 Etiology; 1.6.3 Clinical Features of RSE

1.6.3.1 New-Onset Refractory Status Epilepticus1.6.3.2 Refractory Status Epilepticus in Patients with Preexisting Epilepsy with Initial Treatment Failure; 1.6.3.3 Special Types of RSE; 1.6.4 Treatment for RSE; 1.6.5 Prognosis of RSE; References; 2: Pathogenesis of Refractory Status Epilepticus; 2.1 Mechanism of Seizure Termination; 2.1.1 The Characteristics of Seizure Self-Limitation; 2.1.2 Factors Related to Seizure Self-Limitation; 2.1.3 Potential Mechanism of Seizure Self-Limitation; 2.1.4 Conclusion; 2.2 The Pathogenesis of SE

2.2.1 Changes in the Internal Environment During SE2.2.2 The Pathogenesis of SE; 2.2.3 Conclusions; 2.3 The Pathogenesis of RSE; 2.3.1 Translocation of GABA and Glutamate Receptors; 2.3.2 Neuronal Injury and Death; 2.3.3 Changes in the Expression of Neuropeptides; 2.3.4 Inflammatory Process; 2.3.5 Changes in Gene Expression; 2.3.6 Conclusions; References; 3: Brain Damage Caused by Status Epilepticus; 3.1 Introduction; 3.2 Clinical Evidence and the Chronology of Brain Damage During and After SE; 3.3 Animal Experimental Evidence of Brain Damage During and After SE

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