000799926 000__ 04930cam\a2200457M\\4500 000799926 001__ 799926 000799926 005__ 20230306143651.0 000799926 006__ m\\\\\o\\d\\\\\\\\ 000799926 007__ cr\un\nnnunnun 000799926 008__ 170919s2017\\\\sz\\\\\\o\\\\\000\0\eng\d 000799926 019__ $$a1004225398$$a1004357485$$a1004460826$$a1008875918$$a1011990066 000799926 020__ $$a9783319591926$$q(electronic book) 000799926 020__ $$a3319591924$$q(electronic book) 000799926 020__ $$z9783319591919 000799926 020__ $$z3319591916 000799926 0247_ $$a10.1007/978-3-319-59192-6$$2doi 000799926 035__ $$aSP(OCoLC)on1004612026 000799926 035__ $$aSP(OCoLC)1004612026$$z(OCoLC)1004225398$$z(OCoLC)1004357485$$z(OCoLC)1004460826$$z(OCoLC)1008875918$$z(OCoLC)1011990066 000799926 040__ $$aYDX$$beng$$cYDX$$dN$T$$dGW5XE$$dN$T$$dOCLCF$$dNJR 000799926 049__ $$aISEA 000799926 050_4 $$aRS165.W58 000799926 08204 $$a615.3/21$$223 000799926 24500 $$aScience of Ashwagandha :$$bpreventive and therapeutic potentials /$$cSunil C. Kaul, Renu Wadhwa, editors. 000799926 260__ $$aCham :$$bSpringer,$$c2017. 000799926 300__ $$a1 online resource. 000799926 336__ $$atext$$btxt$$2rdacontent 000799926 337__ $$acomputer$$bc$$2rdamedia 000799926 338__ $$aonline resource$$bcr$$2rdacarrier 000799926 5050_ $$aPART I Ashwagandha -- Phytogenomics and Pharmacology -- Phytochemical Genomics of Ashwagandha -- Phyto-pharmacology of Ashwagandha as An Anti-Diabetic Herb -- Allium cepa Root Chromosomal Aberration Assay: An Application in Assessing Anti-genotoxic Potential of Ashwagandha -- Withania somnifera: From Traditional Use to Evidence Based Medicinal Prominence -- Withanolides: A Prospective Drug for Infectious and Tropical Diseases -- Withania somnifera Extract/Withaferin A As A Prospective Anti-pigmenting Agent -- PART II Ashwagandha for Cancer -- Ashwagandha Bioactives for Cancer Treatment: Experimental Evidence and Their Mechanism(s) of Action -- Scientific Evidence for Anticancer Effects of Withania somnifera And its Primary Bioactive Component Withaferin A -- Withaferin A for Cancer Treatment: Experimental Evidence for its Effect on Telomerase Plus and Minus Cancer Cells -- Withania somnifera Has Potential to Treat Cancer -- The Effects of Withaferin A on Normal And Malignant Immune Cells -- Ashwagandha for Cancer Metastasis: Bioactives and Basics of their Function -- Computational Methods to Understand The Anticancer Mechanism of Withanolides -- PART III Ashwagandha for Brain -- Ashwagandha for Brain Health: Experimental Evidence to its Neuroregenerative Activities -- Cellular and Molecular Targets Underpinning Memory Enhancement by Ashwagandha -- Using Human Neural Stem Cells as A Model to Understand The Science of Ashwagandha -- The Potential Utility of Ashwagandha for Improving Cognitive Dysfunction in Persons with Bipolar or Other Neurocognitive Disorders -- Neuroprotective Potential of Withania somnifera (Ashwagandha) in Neurological Conditions -- Potential Therapeutic Use of Withania somnifera for Treatment of Amyotrophic Lateral Sclerosis -- Neuromodulatory Role of Withania somnifera -- Therapeutic Effects of Ashwagandha in Brain Aging and Clock Disfunction -- PART IV Active Ingredient Enriched Ashwagandha -- Biotechnologies -- Biotechnological Approaches in Propagation And Improvement of Withania somnifera (L.) Dunal -- Plant Tissue Culture Based Strategies for Production of Withanolides -- Establishment of Hydroponic Cultivation of Ashwagandha for Active Ingredient Enriched Leaves. 000799926 506__ $$aAccess limited to authorized users. 000799926 520__ $$aRapidly increasing aging population and environmental stressors are the two main global concerns of increasing incidence of a variety of pathologies in the modern society. The complex etiologies and pathologies cause major challenges to disease treatment. On the other hand, several herbs are known for their health-caring and disease-curing activities. Ashwagandha, a popular herb in Indian traditional home medicine, Ayurveda, has gathered increasing recognition in recent years when the chemically synthesized drugs for single target therapies showed limited success and adverse toxic effects. Ashwagandha is known as a powerful adaptogen and trusted to enhance function of the brain, reproductive system, cell-mediated immunity and increase the body's defense against disease, and possess anti-inflammatory, anticancer and anti-arthritic activities. In this book, for the first time, we provide a complete portrait on scientific understanding of the effects of Ashwagandha and its active principles for a variety of preventive and therapeutic activities. 000799926 588__ $$aDescription based on print version record. 000799926 650_0 $$aWithania somnifera. 000799926 650_0 $$aMedicinal plants$$zIndia. 000799926 7001_ $$aKaul, Sunil. 000799926 7001_ $$aWadhwa, Renu. 000799926 77608 $$iPrint version:$$z9783319591919$$z3319591916$$w(OCoLC)985082621 000799926 85280 $$bebk$$hSpringerLink 000799926 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-59192-6$$zOnline Access$$91397441.1 000799926 909CO $$ooai:library.usi.edu:799926$$pGLOBAL_SET 000799926 980__ $$aEBOOK 000799926 980__ $$aBIB 000799926 982__ $$aEbook 000799926 983__ $$aOnline 000799926 994__ $$a92$$bISE