000800062 000__ 04685cam\a2200553M\\4500
000800062 001__ 800062
000800062 005__ 20230306143659.0
000800062 006__ m\\\\\o\\d\\\\\\\\
000800062 007__ cr\un\nnnunnun
000800062 008__ 170927s2017\\\\sz\\\\\\o\\\\\000\0\eng\d
000800062 019__ $$a1004563594$$a1004938166
000800062 020__ $$a9783319632605$$q(electronic book)
000800062 020__ $$a3319632604$$q(electronic book)
000800062 020__ $$z9783319632599
000800062 020__ $$z3319632590
000800062 035__ $$aSP(OCoLC)on1004763717
000800062 035__ $$aSP(OCoLC)1004763717$$z(OCoLC)1004563594$$z(OCoLC)1004938166
000800062 040__ $$aYDX$$beng$$cYDX$$dN$T$$dEBLCP$$dGW5XE$$dN$T$$dYDX$$dNJR
000800062 049__ $$aISEA
000800062 050_4 $$aRC346
000800062 066__ $$c(S
000800062 08204 $$a616.8/0471$$223
000800062 08204 $$a610
000800062 24500 $$aObesity and brain function /$$cLiliana Letra, Raquel Seiça, editors.
000800062 260__ $$aCham :$$bSpringer,$$c2017.
000800062 300__ $$a1 online resource.
000800062 336__ $$atext$$btxt$$2rdacontent
000800062 337__ $$acomputer$$bc$$2rdamedia
000800062 338__ $$aonline resource$$bcr$$2rdacarrier
000800062 4901_ $$aAdvances in neurobiology,$$x2190-5215 ;$$vv. 19
000800062 5050_ $$6880-01$$aPreface; Contents; Part I: Adipose Tissue Biology and Crosstalks; Chapter 1: Function and Dysfunction of Adipose Tissue; 1.1 Adipose Tissue Structure; 1.2 Metabolic Functions of the Adipose Tissue; 1.2.1 Mechanisms of Nutrient Uptake and Storage in Adipocytes; 1.2.2 Cholesterol Fluxes; 1.3 Endocrine Function of the Adipose Tissue; 1.3.1 Leptin; 1.3.2 Adiponectin; 1.3.3 Resistin; 1.3.4 Other Adipose Tissue Products; 1.4 Dysregulation of Adipose Tissue Function in Obesity; 1.4.1 Dysregulation of Lipid Metabolism; 1.4.2 Adipose Tissue Hypoxia
000800062 5058_ $$a2.2 Brain Circuits of Food Intake Regulation2.2.1 Hypothalamus; 2.2.1.1 Arcuate Nucleus; 2.2.1.2 Paraventricular Nucleus; 2.2.1.3 Ventromedial Hypothalamus and Dorsomedial Hypothalamus; 2.2.1.4 Lateral Hypothalamic Area; 2.2.1.5 Glucose and Lipid Sense Neurons; 2.2.2 Brainstem; 2.2.3 Brain Reward Circuits; 2.3 Neuronal and Humoral Outputs to the Peripheral Organs; 2.3.1 Central Nervous System and White Adipose Tissue; 2.3.2 Central Nervous System and Brown Adipose Tissue; 2.4 Concluding Remarks; References; Chapter 3: Neuroendocrinology of Adipose Tissue and Gut-Brain Axis; 3.1 Introduction
000800062 5058_ $$a3.2 Gastrointestinal Signals to the Brain3.2.1 Orexigenic Factors; 3.2.1.1 Ghrelin; 3.2.1.2 Endocannabinoids; 3.2.2 Anorexigenic Factors; 3.2.2.1 Cholecystokinin; 3.2.2.2 Glucagon-like-Peptide-1; 3.2.2.3 Glucagon-like Peptide-2; 3.2.2.4 Peptide Tyrosine Tyrosine; 3.2.2.5 Oxyntomodulin; 3.2.2.6 Gastric Leptin; 3.2.2.7 Apolipoprotein-IV; 3.2.2.8 Neurotensin; 3.2.2.9 Secretin; 3.2.2.10 GUT Microbiota; 3.3 Endocrine Pancreas-Derived Signals to the Brain; 3.3.1 Insulin; 3.3.2 Glucagon; 3.3.3 Amylin; 3.3.4 Pancreatic Polypeptide; 3.4 Adipose Tissue-Derived Signals to the Brain; 3.4.1 Leptin
000800062 5058_ $$a3.4.2 Adiponectin3.4.3 Resistin; 3.4.4 Apelin; 3.5 Concluding Remarks; References; Part II: Obesity as a Risk Factor for Neurological Disease; Chapter 4: Hypothalamic Dysfunction in Obesity and Metabolic Disorders; 4.1 Introduction; 4.2 Changes of Hypothalamic Food Intake Regulation Controlled by the Hypothalamus; 4.2.1 Obesity Induces Insulin, Leptin, and Ghrelin Resistance in the Hypothalamus; 4.2.1.1 Hypothalamic Insulin Resistance in Obesity; 4.2.1.2 Hypothalamic Leptin Resistance in Obesity; 4.2.1.3 Hypothalamic Ghrelin Resistance in Obesity
000800062 506__ $$aAccess limited to authorized users.
000800062 520__ $$aThis compendium provides a wide view covering everything from molecular mechanisms and risk factors for neurological disorders to the effects of bariatric surgery on brain function and functional neuroimaging applied to obesity research. The impact of obesity on brain function and the development of neurodegenerative and neuroinflammatory disorders has been understudied, despite the recent proliferation of obesity research. Among the topics covered are adipose biology, the adipose tissue - gut - brain axis, brain energy metabolism, dementia, cerebrovascular disease, and multiple sclerosis.
000800062 588__ $$aDescription based on print version record.
000800062 650_0 $$aNervous system$$xDiseases$$xRisk factors.
000800062 650_0 $$aObesity$$xMolecular aspects.
000800062 650_0 $$aNervous system$$xDiseases$$xMolecular aspects.
000800062 650_0 $$aNeuroendocrinology.
000800062 7001_ $$aLetra, Liliana.
000800062 7001_ $$aSeica, Raquel.
000800062 77608 $$iPrint version:$$z9783319632599$$z3319632590$$w(OCoLC)992746043
000800062 830_0 $$aAdvances in neurobiology ;$$v19.
000800062 852__ $$bebk
000800062 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-63260-5$$zOnline Access$$91397441.1
000800062 909CO $$ooai:library.usi.edu:800062$$pGLOBAL_SET
000800062 980__ $$aEBOOK
000800062 980__ $$aBIB
000800062 982__ $$aEbook
000800062 983__ $$aOnline
000800062 994__ $$a92$$bISE