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Introduction; Part I: Conceptual Questions of Memory Consolidation; Part II: Memory Consolidation During Off-Line Periods and the Role of Sleep; Part III: Mechanisms of Memory Consolidation on a Systems Physiology Level; Part IV: Modulation of Memory Consolidation; Part V: Clinical Translation; References; Conceptual Questions of Memory Consolidation; 1 Cellular and Systems Consolidation of Declarative Memory; Abstract; Introduction; Cellular Consolidation; Systems Consolidation; Interaction of Cellular and Systems Consolidation; Conclusion; References.
2 Mechanisms of Memory Consolidation and TransformationAbstract; Introduction; How Does a Memory Trace Form? Mechanisms of Cellular Consolidation; How Does a Memory Trace Change Over Time? Reorganization and Distribution of the Memory Network; A Case for the Transformation of Spatial Memory; Evidence for Systems Consolidation and Memory Transformation in the Healthy Rodent Brain; Limitations to Rodent Models of Memory Consolidation; Evidence for Systems Consolidation and Memory Transformation in the Healthy Human Brain; What Are the Mechanisms of Systems Consolidation?
Timeline of Systems ConsolidationConclusion: Transforming the Concept of Consolidation; Acknowledgements; References; 3 The Medial Prefrontal Cortex is a Critical Hub in the Declarative Memory System; Abstract; References; 4 Consolidation of Episodic Memory: An Epiphenomenon of Semantic Learning; Abstract; Introduction; Theoretical Accounts of Consolidation: Transfer Versus Transformation; The Distinction Between Episodic and Semantic Memory; The Component-Structure of Episodic Memory; Semantic Representations and Information; Sequential Episodic Memory Traces; Scenario Generation.
Evidence for the Component Nature of Episodic MemoryNovel Account of Systems Consolidation; Learning Associations Across Time Gaps; Conclusion; Acknowledgements; References; Memory Consolidation During Off-Line Periods and the Role of Sleep; 5 The Impact of Sleep Deprivation on Molecular Mechanisms of Memory Consolidation in Rodents; Abstract; Introduction; Molecular Mechanisms of Memory Consolidation; cAMP-PKA Signaling Cascade as Key Modulator During Memory Consolidation; Critical Time Windows During Memory Consolidation.
Sleep Deprivation Impairs Molecular Targets Important for Memory ConsolidationSleep Deprivation Impairs CAMP-PKA Signaling and Influences Downstream Targets; Sleep Deprivation Impairs Gene Expression; Sleep Deprivation Impairs Translation; Conclusion; Acknowledgements; References; 6 Sleep and Odor Memory Consolidation in Non-human Animal Models; Abstract; Introduction; Olfactory System Anatomy and Physiology; Odor Memory; Sleep and Olfactory System Function; Sleep and Odor Memory Consolidation; Summary; Acknowledgements; References; 7 The Effect of Sleep on Multiple Memory Systems; Abstract.
2 Mechanisms of Memory Consolidation and TransformationAbstract; Introduction; How Does a Memory Trace Form? Mechanisms of Cellular Consolidation; How Does a Memory Trace Change Over Time? Reorganization and Distribution of the Memory Network; A Case for the Transformation of Spatial Memory; Evidence for Systems Consolidation and Memory Transformation in the Healthy Rodent Brain; Limitations to Rodent Models of Memory Consolidation; Evidence for Systems Consolidation and Memory Transformation in the Healthy Human Brain; What Are the Mechanisms of Systems Consolidation?
Timeline of Systems ConsolidationConclusion: Transforming the Concept of Consolidation; Acknowledgements; References; 3 The Medial Prefrontal Cortex is a Critical Hub in the Declarative Memory System; Abstract; References; 4 Consolidation of Episodic Memory: An Epiphenomenon of Semantic Learning; Abstract; Introduction; Theoretical Accounts of Consolidation: Transfer Versus Transformation; The Distinction Between Episodic and Semantic Memory; The Component-Structure of Episodic Memory; Semantic Representations and Information; Sequential Episodic Memory Traces; Scenario Generation.
Evidence for the Component Nature of Episodic MemoryNovel Account of Systems Consolidation; Learning Associations Across Time Gaps; Conclusion; Acknowledgements; References; Memory Consolidation During Off-Line Periods and the Role of Sleep; 5 The Impact of Sleep Deprivation on Molecular Mechanisms of Memory Consolidation in Rodents; Abstract; Introduction; Molecular Mechanisms of Memory Consolidation; cAMP-PKA Signaling Cascade as Key Modulator During Memory Consolidation; Critical Time Windows During Memory Consolidation.
Sleep Deprivation Impairs Molecular Targets Important for Memory ConsolidationSleep Deprivation Impairs CAMP-PKA Signaling and Influences Downstream Targets; Sleep Deprivation Impairs Gene Expression; Sleep Deprivation Impairs Translation; Conclusion; Acknowledgements; References; 6 Sleep and Odor Memory Consolidation in Non-human Animal Models; Abstract; Introduction; Olfactory System Anatomy and Physiology; Odor Memory; Sleep and Olfactory System Function; Sleep and Odor Memory Consolidation; Summary; Acknowledgements; References; 7 The Effect of Sleep on Multiple Memory Systems; Abstract.