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Foreword; Preface; Contents; 1: Anatomy; 1.1 Anatomy of the Anorectum; 1.2 Definition of Anal Fissure; References; Anatomy; 2: Chronic Anal Fissure; 2.1 Morphology; 2.2 Location; 2.3 Age Distribution; 2.4 Gender Distribution; 2.5 Duration of Anal Fissure Disease; 2.6 Secondary Changes; 2.6.1 Hypertrophied Anal Papilla; 2.6.2 Anal Cryptitis; 2.6.3 Sentinel Tags; 2.6.4 Anal Fistula/Abscess; References; Location; Age Distribution; Gender Distribution; Duration of Anal Fissure Disease; Hypertrophied Anal Papilla; Anal Cryptitis; Sentinel Tags; Anal Fistula/Abscess.

3: Secondary Anal Fissures3.1 Associated with Ulcerative Colitis; 3.2 Associated with Crohn's Disease; 3.3 Induced by Infectious Pathogens; 3.3.1 Syphilis; 3.3.2 Tuberculosis; 3.3.3 Leishmaniasis; 3.3.4 Histoplasmosis; 3.3.5 Virally Induced; 3.3.5.1 HIV/AIDS; 3.3.5.2 Herpes Simplex Viruses (HSV); 3.3.5.3 Cytomegaloviruses (CMV); 3.4 Drug-Induced; 3.4.1 Ergotamine; 3.4.2 Nicorandil; 3.4.3 Isotretinoin; 3.4.4 Chemotherapeutics; 3.5 Other Pathological Causes; 3.5.1 Leukemia; 3.5.2 Cow's Milk Allergy; 3.5.3 Behçet's Disease; References; Associated with Ulcerative Colitis.

Associated with Crohn's DiseaseInduced by Infectious Pathogens; Syphilis; Tuberculosis; Leishmaniasis; Histoplasmosis; Virally Induced; HIV/AIDS; Herpes Simplex Viruses (HSV); Cytomegaloviruses (CMV); Nicorandil; Isotretinoin; Chemotherapeutics; Other Pathological Causes; Leukemia; Cow's Milk Allergy; Behçet's Disease; 4: Problems of Defining Chronic Anal Fissure; References; 5: Epidemiology and Etiopathogenesis; 5.1 Epidemiology; 5.1.1 Anal Fissures in Children and Juveniles; 5.2 Etiopathogenesis; 5.2.1 Anal Sphincter Hypertonia; 5.2.2 Anal Sphincter Fibrosis; 5.2.3 Traumata.

5.2.4 Anal Abuse5.2.5 Anal Sexual Practices; 5.2.6 Infection; 5.2.7 Ischemia; 5.2.8 Anatomical Causes; References; Epidemiology and Etiopathogenesis; Anal Fissures in Children and Juveniles; Anal Sphincter Hypertonia; Anal Sphincter Fibrosis; Traumata, Anal Abuses and Anal Sexual Practices; Infection; Ischemia; Anatomical Causes; 6: Signs and Symptoms; 6.1 Anorectal Pain; 6.2 Anal Bleeding; 6.3 Anal Pruritus; 6.4 Constipation; References; Anorectal Pain; Anal Bleeding; Anal Pruritus; Constipation; 7: Anal Fissure Disease: Prevention and Quality of Life; 7.1 Prevention.

7.2 Anal Fissure Disease and Quality of LifeReferences; Prevention; Anal Fissure Disease and Quality of Life; 8: Diagnostics and Differential Diagnostics; 8.1 Diagnostics; 8.1.1 Anamnesis; 8.1.2 Medical Examination; 8.2 Differential Diagnosis; 8.2.1 Preliminary Note; 8.2.1.1 Erosions; 8.2.1.2 Rhagades; 8.2.1.3 Anal Ulcers; 8.2.1.4 Anal Carcinoma; 8.2.1.5 Anorectal Pain Syndromes; Proctalgia Fugax; Anogenital Syndrome (AGS); Coccygodynia; References; 9: Historical Aspects of Anal Fissure Pathology; 9.1 Signs and Symptoms; 9.2 Etiopathogenesis; 9.3 Medical Findings.

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