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000807136 020__ $$a9783319492278$$q(electronic book)
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000807136 0247_ $$a10.1007/978-3-319-49227-8$$2doi
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000807136 050_4 $$aRC454.4$$b.G46 2017
000807136 08204 $$a616.89$$223
000807136 24500 $$aGene-environment transactions in developmental psychopathology :$$bthe role in intervention research /$$cPatrick H. Tolan, Bennett L. Leventhal, editors.
000807136 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2017]
000807136 300__ $$a1 online resource.
000807136 336__ $$atext$$btxt$$2rdacontent
000807136 337__ $$acomputer$$bc$$2rdamedia
000807136 338__ $$aonline resource$$bcr$$2rdacarrier
000807136 347__ $$atext file$$bPDF$$2rda
000807136 4901_ $$aAdvances in development and psychopathology. Brain Research Foundation symposium series
000807136 504__ $$aIncludes bibliographical references and index.
000807136 5050_ $$aContributors; Chapter 1: What Can and Should Be the Role of Intervention Studies in GEX Research?; Gene-Environmental Transaction Framework for Intervention Research; References; Part I: Gene-Environment Transaction Framework; Chapter 2: Genetics, Behavioral Intervention, and Human Development; Defining Targets for Behavioral Intervention; Defining Groups of Individuals at Risk for Disease; Delineating Malleable Mechanisms of Gene Expression; Defining the Timing of Behavioral Interventions; Genetic Influences on Response to Treatment; A Few Ideas About the Future; Summary.
000807136 5058_ $$aProspects for Detecting G?E in Intervention ResearchReferences; Chapter 4: Epigenetics and the Biology of Gene? Environment Interactions; Epigenetics and the Biological Basis of G? E Interactions; Histone Modifications; DNA Methylation; Epigenetics and Development; Epigenetics and the Biology of G? E Interactions; Epigenetic Regulation of GR Expression and Function in Humans; Environmental Regulation of the Human Methylome; The Epigenome as a Function of Gene? Environment Interactions: Allele-Specific Methylation; Gene x Environment Effects: Plasticity Genes?
000807136 5058_ $$aImplications for Prevention Programmes Conclusions; References; Chapter 5: Using Genetically Informed Designs to Understand the Environment: The Importance of Family-Based Approaches; Family-Based Behavioral Genetic Designs; Challenges to Family-Based Behavioral Genetic Designs; Conceptual Issues; Technical Issues; The Continued Value of Family-Based Behavioral Genetic Designs; Response to Conceptual Criticisms; Response to Technical Criticisms; The Value of Family-Based Behavioral Genetic Studies; The Implications of Family-Based Behavioral Genetic Studies on Intervention Science.
000807136 5058_ $$aConclusions and Future DirectionsReferences; Chapter 6: Gene-Environment Correlation as a Source of Stability and Diversity in Development; A Brief but Successful Baseball Career; If Monkeys Could Play Baseball; Plomin, Loehlin and DeFries (1977); Heritability Increases with Age; The Question of How; Tucker-Drob and Briley; Phenotype to Environment Transmission and Gene-Environment Correlation; Applications to Childhood Intervention; Back to Baseball; References; Chapter 7: Sampling in the Examination of Gene-ƯEnvironmental Interactions Within a Neurodevelopmental Disorder Framework.
000807136 506__ $$aAccess limited to authorized users.
000807136 520__ $$aThis book examines the current research in gene-environment transactions (GEX) and its potential use in developing interventions and applications tailored to individual genetic makeups. Key concepts underlying GEX studies in this area are defined, identifying fundamental challenges in devising informed research questions and conducting valid and useful experiments. Chapters analyze GEX models inspired by the present day genome-based frameworks, particularly in terms of advances in identifying and understanding complex environmental factors, using examples from common psychological conditions, such as antisocial behavior, chronic physical aggression, and chronic internalizing disorder. In addition, the book presents new and potential applications of the framework in the contexts of prevention science and intervention research. Topics featured in this book include: Epigenetics and the biology of gene x environment interactions. Gene by environment interactions and its potential use for intervention strategies in anxiety disorders. The challenges and potential for research on gene-environment interactions within autism spectrum disorder. Using genetically informed prevention trials to test gene x environment hypothese. Challenges for intervention research within the GEX framework. Gene-Environment Transactions in Developmental Psychopathology is a must-have resource for researchers/professors, clinicians, and related professionals as well as graduate students in developmental psychology, psychiatry, human genetics, and related disciplines.
000807136 588__ $$aOnline resource; title from digital title page (viewed on May 24, 2017).
000807136 650_0 $$aPsychology, Pathological.
000807136 650_0 $$aGenotype-environment interaction.
000807136 7001_ $$aTolan, Patrick H.,$$eeditor.
000807136 77608 $$iPrint version:$$z9783319492254
000807136 830_0 $$aAdvances in development and psychopathology.$$pBrain Research Foundation symposium series.
000807136 852__ $$bebk
000807136 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-49227-8$$zOnline Access$$91397441.1
000807136 909CO $$ooai:library.usi.edu:807136$$pGLOBAL_SET
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000807136 980__ $$aBIB
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000807136 983__ $$aOnline
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