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000807167 019__ $$a992522778$$a992930600$$a999369754$$a1005821256$$a1011950834
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000807167 24500 $$aSepsis :$$bdefinitions, pathophysiology and the challenge of bedside management /$$cNicholas S. Ward, Mitchell M. Levy, editors.
000807167 264_1 $$aCham :$$bHumana Press,$$c2017.
000807167 300__ $$a1 online resource.
000807167 336__ $$atext$$btxt$$2rdacontent
000807167 337__ $$acomputer$$bc$$2rdamedia
000807167 338__ $$aonline resource$$bcr$$2rdacarrier
000807167 347__ $$atext file$$bPDF$$2rda
000807167 4901_ $$aRespiratory medicine,$$x2197-7372
000807167 504__ $$aIncludes bibliographical references and index.
000807167 5050_ $$6880-01$$aPreface; Contents; Contributors; Part I; Chapter 1: Introduction; References; Chapter 2: Sepsis Definitions; Introduction; History of the Definition of Sepsis; Origins of the Definition of Sepsis; 1991 International Consensus Conference; 2001 International Consensus Conference; 2010 Merinoff Symposium; 2016 The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3); Difficulties in Defining Sepsis; Shortcomings of the SIRS Criteria; Staging of Sepsis; Problems with in Early Stage Sepsis; Adoption of the Term "Septic" in Medical Culture.
000807167 5058_ $$aDefining Sepsis Through Clinical or Administrative Data Coding; Criteria; Angus Criteria; Martin Criteria; Comparison of Different Methods; Trends in Mortality and Disability in Sepsis; Future Directions; Conclusions; References; Chapter 3: Epidemiology of Sepsis: Current Data and Predictions for the Future; Introduction; Incidence and Outcome of Sepsis; Global Cohorts; The Cost of Sepsis; Long-Term Outcomes; Demographic and Genetic Factors; Gender; Race; Socioeconomic Status; Biological Factors; Comorbidities; Malignancy; HIV; Obesity; Diabetes.
000807167 5058_ $$aAnti-Inflammatory Cytokines IL-10; Chemotactic Cytokines; Complement and Coagulation Cascades; Antimicrobial Peptides; Lipid Mediators; Prostanoids and Leukotriene; Reactive Oxygen Species (ROSs), Reactive Nitrogen Species (RNSs), and Nitric Oxide (NO); Immune Resolution of Sepsis; Summary; References; Chapter 5: Sepsis-Induced Immune Suppression; Introduction; Cytokines in Sepsis-Induced Immune Suppression; The Role of Immune Cells in Sepsis-Induced Immunosuppression; Impaired Immune Cell Function and Programmed Cell Death in Sepsis; Neutrophils; Antigen Presenting Cells.
000807167 506__ $$aAccess limited to authorized users.
000807167 520__ $$aThis book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early severe sepsis. Care of these patients and clinical conditions can be quite complex, and materials are collected from the most current, evidence-based resources. Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis. This review summarizes the evidence for the international consensus guidelines for the identification and management of sepsis. The latter part of this book reviews emerging concepts and approaches in the diagnosis and management of sepsis that may significantly reduce mortality in the future. Sepsis: Pathophysiology, Definitions and the Challenge of Bedside Management represents a collaboration between authors drawn from a variety of disciplines and contributions from basic scientists and highly recognized clinical opinion leaders with expertise in clinical trials.
000807167 588__ $$aOnline resource; title from PDF title page (viewed June 8, 2017).
000807167 650_0 $$aSepticemia.
000807167 7001_ $$aWard, Nick,$$d1964-$$eeditior.
000807167 7001_ $$aLevy, Mitchell M.,$$d1950-$$eeditior.
000807167 77608 $$iPrint version:$$z9783319484686
000807167 830_0 $$aRespiratory medicine (New York, N.Y.)
000807167 85280 $$bebk$$hSpringerLink
000807167 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-48470-9$$zOnline Access$$91397441.1
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000807167 980__ $$aEBOOK
000807167 980__ $$aBIB
000807167 982__ $$aEbook
000807167 983__ $$aOnline
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