Managing discovery in the life sciences : harnessing creativity to drive biomedical innovation / Philip A. Rea, University of Pennsylvania, Mark V. Pauly, University of Pennsylvania, Lawton R. Burns, University of Pennsylvania.

Discoveries now and then : Shifting incentives and expectations
Pharma trends : Not what they seem
Profit-maximizing drug firms : models and myths
The statins : Cholesterol's "Penicillins"
ACE inhibitors : Kidney clamps, snake venoms and peptidomimetics
Angioplasty : Catheters, guidewires, and balloons
Hepatitus C : When cures and prices go viral
Alzheimer's : America's most feared disease
Meftormin : To the brink and back
Medical Genomics : Personalized precision
Gleevec : From broken chromosomes to precision cancer therapy
Regeneron : Agility, resilience, and balance
Avastin and Lucentis : Both for eyesight in hindsight
CAR T-cell Therapy : Cures for ALL and more?
Organizing discovery : Wild ducks nested in multilevel ecosystems
Can government help with the creatively unexpected?