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Evolution of the human genome I : the genome and genes / edited by Naruya Saitou.

Saitou, Naruya. editor.
2017
QH359-425
Available Online
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Title
Evolution of the human genome I : the genome and genes / edited by Naruya Saitou.
ISBN
9784431566038
4431566031
9784431566014
DOI
https://doi.org/10.1007/978-4-431-56603-8
Published
Tokyo : Springer Japan : Imprint: Springer, 2017.
Language
English
Description
1 online resource (viii, 305 pages) : illustrations.
Item Number
10.1007/978-4-431-56603-8 doi
Call Number
QH359-425
Dewey Decimal Classification
576.8
Summary
This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by Ryosuke Kimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field.
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Added Author
Saitou, Naruya. editor.
Series
Evolutionary Studies.
Available in Other Form
Print version: 9784431566014
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Preface
Part I: Overview of the Human Genome
Chapter 1: Human evolution and human genome at a glance
Chapter 2: Rubbish DNA: The functionless fraction of the human genome
Chapter 3: GC content heterogeneity
Chapter 4: Protein-coding and non-coding RNA genes
Chapter 5: Duplicated genes
Chapter 6: Recombination.-Chapter 7: CNVs and microsatellite DNA polymorphism.-Part II: The Human Genome Viewed through Genes.-Chapter 8: Genes on X and Y chromosomes
Chapter 9: Human Leukocyte Antigen (HLA) region in human population studies.-Chapter 10: Evolution of genes for color vision and the chemical senses in primates.-Chapter 11: Global landscapes of human phenotypic variation in inherited traits
Chapter 12: Transcription factor genes
Chapter 13: Genetics of diabetes: are they thrifty genotype?
Chapter 14: Disease-related genes from population genetic aspect and their functional significance
Chapter 15: Microbe genomes associated with human body.-Index.

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