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Title
RNA therapeutics.
ISBN
9783319680910
3319680919
9783319680903
3319680900
Published
Cham : Springer International Publishing, 2017.
Language
English
Description
1 online resource (263 pages).
Item Number
10.1007/978-3-319-68091-0 doi
Call Number
QD1-999
Dewey Decimal Classification
540
Summary
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Description based on print version record.
Series
Topics in Medicinal Chemistry.
Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching
A Modular Approach to the Discovery and Affinity Maturation of Sequence-Selective RNA-Binding Compounds
Structure-Based Discovery of Small Molecules Binding to RNA
Approaches for the Discovery of Small Molecule Ligands Targeting microRNAs
Viral RNA Targets and Their Small Molecule Ligands
Drugging Pre-mRNA Splicing
Targeting RNA G-Quadruplexes for Potential Therapeutic Applications
The Therapeutic Targeting of Long Noncoding RNA
Messenger RNA as a Novel Therapeutic Approach.
