Investigations of cellular and molecular biophysical properties by atomic force microscopy nanorobotics / Mi Li.

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Investigations of cellular and molecular biophysical properties by atomic force microscopy nanorobotics / Mi Li.

9789811068294 (electronic book)
9811068291 (electronic book)
9789811068287
9811068283

Singapore : Springer, ©2018.

English

1 online resource.

10.1007/978-981-10-6829-4 doi

QH212.A78

620/.5

This book presents methodological and application research in detecting cellular and molecular biophysical properties based on atomic force microscopy (AFM) nanorobotics. Series methods for in situ label-free visualizing and quantifying the multiple physical properties of single cells and single molecules were developed, including immobilization strategies for observing fine structures of living cells, measurements of single-cell mechanics, force recognition of molecular interactions, and mapping protein organizations on cell surface. The biomedical applications of these methods in clinical lymphoma treatments were explored in detail, including primary sample preparation, cancer cell recognition, AFM detection and data analysis. Future directions about the biomedical applications of AFM are also given.

"Doctoral thesis accepted by University of Chinese Academy of Sciences, Beijing, China."

Includes bibliographical references.

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Online resource; title from PDF title page (viewed October 17, 2017).

Springer theses.

Print version: 9789811068287

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