Design and evaluation of plasmonic/magnetic Au-MFe2O4 (M-Fe/Co/Mn) core-shell nanoparticles functionalized with doxorubicin for cancer therapeutics / Ravichandran Manisekaran.
2018
RS201.N35
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Title
Design and evaluation of plasmonic/magnetic Au-MFe2O4 (M-Fe/Co/Mn) core-shell nanoparticles functionalized with doxorubicin for cancer therapeutics / Ravichandran Manisekaran.
Author
ISBN
9783319676098 (electronic book)
3319676091 (electronic book)
9783319676081
3319676083
3319676091 (electronic book)
9783319676081
3319676083
Publication Details
Cham : Springer, ©2018.
Language
English
Description
1 online resource (199 pages).
Item Number
10.1007/978-3-319-67609-8 doi
Call Number
RS201.N35
Dewey Decimal Classification
620/.5
620
620
Summary
This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.
Note
"Doctoral thesis accepted by Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), Mexico City."
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Includes bibliographical references.
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text file PDF
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Description based on print version record.
Series
Springer theses.
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