000824706 000__ 04715cam\a2200529Ki\4500
000824706 001__ 824706
000824706 005__ 20230306144135.0
000824706 006__ m\\\\\o\\d\\\\\\\\
000824706 007__ cr\cn\nnnunnun
000824706 008__ 171125s2018\\\\sz\\\\\\ob\\\\001\0\eng\d
000824706 019__ $$a1012775976$$a1017858819$$a1032270240
000824706 020__ $$a9783319596327$$q(electronic book)
000824706 020__ $$a3319596322$$q(electronic book)
000824706 020__ $$z9783319596310
000824706 020__ $$z3319596314
000824706 0247_ $$a10.1007/978-3-319-59632-7$$2doi
000824706 035__ $$aSP(OCoLC)on1012883150
000824706 035__ $$aSP(OCoLC)1012883150$$z(OCoLC)1012775976$$z(OCoLC)1017858819$$z(OCoLC)1032270240
000824706 040__ $$aEBLCP$$beng$$erda$$epn$$cEBLCP$$dN$T$$dGW5XE$$dAZU$$dOCLCF$$dUAB$$dMERER$$dOCLCQ$$dU3W$$dYDX
000824706 049__ $$aISEA
000824706 050_4 $$aQR185.8.M3
000824706 08204 $$a616.07995$$223
000824706 24500 $$aHistiocytic disorders /$$cOussama Abla, Gritta Janka, editors.
000824706 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2018]
000824706 264_4 $$c©2018
000824706 300__ $$a1 online resource (390 pages)
000824706 336__ $$atext$$btxt$$2rdacontent
000824706 337__ $$acomputer$$bc$$2rdamedia
000824706 338__ $$aonline resource$$bcr$$2rdacarrier
000824706 347__ $$atext file$$bPDF$$2rda
000824706 504__ $$aIncludes bibliographical references and index.
000824706 5050_ $$aPathology of Histiocytic Disorders and Neoplasms and Related Disorders -- Biology and Genomics of LCH and Related Disorders -- Epidemiology and Clinical Manifestations of Langerhans Cell Histiocytosis in Children -- Central Nervous System Langerhans Cell Histiocytosis -- First-line Treatment of Pediatric Langerhans Cell Histiocytosis -- Treatment of Relapsed and Refractory Langerhans Cell Histiocytosis in Children -- Adult Langerhans Cell Histiocytosis -- Late Effects of Langerhans Cell Histiocytosis and the Association of LCH with Malignancy -- Classification, Clinical Manifestations and Diagnostics of HLH -- CNS involvement in HLH (CNS-HLH) -- Genetics and Pathogenesis of Haemophagocytic Lymphohistiocytosis -- Hemophagocytic Lymphohistiocytosis Associated with Malignancies and with Epstein Barr Virus -- Macrophage Activation Syndrome in Rheumatic Diseases (MAS-HLH) -- Treatment of Newly Diagnosed HLH and Refractory Disease -- Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic Lymphohistiocytosis -- HLH in Adults -- Juvenile Xanthogranuloma and Related Non-LCH Disorders -- Erdheim-Chester Disease -- Rosai-Dorfman Disease -- Malignant Histiocytoses.
000824706 506__ $$aAccess limited to authorized users.
000824706 520__ $$aThis volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.
000824706 588__ $$aDescription based on print version record.
000824706 650_0 $$aLangerhans cells.
000824706 650_0 $$aMacrophages.
000824706 650_0 $$aLymphatics$$xDiseases.
000824706 650_0 $$aBlood$$xDiseases.
000824706 650_0 $$aImmunologic diseases.
000824706 7001_ $$aAbla, Oussama,$$eeditor.
000824706 7001_ $$aJanka, Gritta,$$eeditor.
000824706 77608 $$iPrint version:$$aAbla, Oussama.$$tHistiocytic Disorders.$$dCham : Springer International Publishing, ©2017$$z9783319596310
000824706 852__ $$bebk
000824706 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-59632-7$$zOnline Access$$91397441.1
000824706 909CO $$ooai:library.usi.edu:824706$$pGLOBAL_SET
000824706 980__ $$aEBOOK
000824706 980__ $$aBIB
000824706 982__ $$aEbook
000824706 983__ $$aOnline
000824706 994__ $$a92$$bISE