Histiocytic disorders / Oussama Abla, Gritta Janka, editors.
Abla, Oussama, editor.; Janka, Gritta, editor.
2018
QR185.8.M3
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Title
Histiocytic disorders / Oussama Abla, Gritta Janka, editors.
ISBN
9783319596327 (electronic book)
3319596322 (electronic book)
9783319596310
3319596314
DOI
https://doi.org/10.1007/978-3-319-59632-7
Published
Cham, Switzerland : Springer, [2018]
Copyright
©2018
Language
English
Description
1 online resource (390 pages)
Item Number
10.1007/978-3-319-59632-7 doi
Call Number
QR185.8.M3
Dewey Decimal Classification
616.07995
Summary
This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.
Bibliography, etc. Note
Includes bibliographical references and index.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Description based on print version record.
Added Author
Abla, Oussama, editor.
Janka, Gritta, editor.
Available in Other Form
Histiocytic Disorders.
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All Resources
Pathology of Histiocytic Disorders and Neoplasms and Related Disorders
Biology and Genomics of LCH and Related Disorders
Epidemiology and Clinical Manifestations of Langerhans Cell Histiocytosis in Children
Central Nervous System Langerhans Cell Histiocytosis
First-line Treatment of Pediatric Langerhans Cell Histiocytosis
Treatment of Relapsed and Refractory Langerhans Cell Histiocytosis in Children
Adult Langerhans Cell Histiocytosis
Late Effects of Langerhans Cell Histiocytosis and the Association of LCH with Malignancy
Classification, Clinical Manifestations and Diagnostics of HLH
CNS involvement in HLH (CNS-HLH)
Genetics and Pathogenesis of Haemophagocytic Lymphohistiocytosis
Hemophagocytic Lymphohistiocytosis Associated with Malignancies and with Epstein Barr Virus
Macrophage Activation Syndrome in Rheumatic Diseases (MAS-HLH)
Treatment of Newly Diagnosed HLH and Refractory Disease
Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic Lymphohistiocytosis
HLH in Adults
Juvenile Xanthogranuloma and Related Non-LCH Disorders
Erdheim-Chester Disease
Rosai-Dorfman Disease
Malignant Histiocytoses.

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